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Wednesday, October 12, 2011

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Physico-chemical properties

7.2 MELTING/FREEZING POINT

7.3 BOILING POINT

7.4 RELATIVE DENSITY

7.5 VAPOUR PRESSURE

7.6 SURFACE TENSION

7.7 WATER SOLUBILITY

7.8 PARTITION COEFFICIENT n-Octanol/Water

7.9 FLASH POINT

7.16 DISSOCIATION CONSTANT

7.17 VISCOSITY

Toxicological group

8.1 SKIN IRRITATION or SKIN CORROSION

8.2 EYE-IRRITATION

8.3 SKIN SENSITIZATION

8.4 MUTAGENICITY

8.4.1 IN-VITRO GENE MUTATION STUDY IN BACTERIA

8.4.2 IN-VITRO CITOGENICITY STUDY IN MAMMALIAN CELLS OR IN-VITRO MICRONUCLEUS STUDY

8.4.4 IN-VIVO MUTAGENICITY STUDY

8.5 ACUTE TOXICITY

8.5.1 ACUTE TOXICITY (by oral route)

8.5.2 ACUTE TOXICITY (by inhalation)

8.6 REPEATED DOSE TOXICITY

8.6.1 SHORT-TERM REPEATED DOSE TOXICITY (28 DAYS)

8.6.2 SUB-CHRONIC TOXICITY STUDY (90 DAYS)

8.6.3 LONG-TERM REPEATED DOSE TOXICITY STUDY (>12 MONTHS)

8.7 REPRODUCTIVE TOXICITY

8.7.1 SCREENING FOR REPRODUCTIVE/DEVELOPMENTAL TOXICITY (OECD 412 - 422)

8.7.2 PRE-NATAL DEVELOPMENTAL TOXICITY STUDY (OECD 414)

8.8 TOXICOKINETICS

8.8.1 ASSESSMENT OF TOXICOKINETIC BEHAVIOR OF THE SUBSTANCE

8.9 CARCINOGENICITY

Environmental Properties & Ecotoxicological Group

9.1 AQUATIC TOXICITY

9.1.1 SHORT-TERM TOXICITY TESTING ON INVERTEBRATES (DAPHNIA)

9.1.2 GROWTH INHIBITION STUDY AQUATIC PLANT (ALGAE PREFERRED)

9.1.3 SHORT-TERM TOXICITY TESTING ON FISH

9.1.4 ACTIVATED SLUDGE RESPIRATION INHIBITION TESTING

9.1.5 LONG-TERM TOXICITY TESTING ON INVERTEBRATES (PREFERRED DAPHNIA)

9.1.6 LONG-TERM TOXICITY TESTING ON FISH

9.2 DEGRADATION [9.2.1 BIOTIC & 9.2.2 ABIOTIC]

9.2.1.1 READY BIODEGRADABILITY

9.2.1.3 SOIL SIMULATION TESTING

9.2.2 ABIOTIC DEGRADATION

9.2.2.1 HYDROLYSIS AS A FUNCTION OF pH

9.2.3 IDENTIFICATION OF DEGRADATION PRODUCTS

9.3 FATE AND BEHAVIOUR IN THE ENVIRONMENT

9.3.1 ABSORPTION / DESORPTION SCREENING

9.3.2 BIOACCUMULATION IN AQUATIC SPECIES, PREFERABLE FISH

9.3.4 FURTHER INFORMATION ON THE ENVIRONMENTAL FATE AND BEHAVIOUR OF THE SUBSTANCE

9.4 EFFECTS ON TERRESTRIAL ORGANISMS

9.4.1 SHORT-TERM TOXICITY TO INVERTEBRATES

9.4.3 SHORT-TERM TOXICITY TO PLANTS

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