The profiling of drug substances as to their physical and analytical characteristics
remains as important today as it was when the Analytical Profiles series was first
initiated. The compilation of concise summaries of physical and chemical data,
analytical methods, routes of compound preparation, degradation pathways, and the
like, is a vital function to both academia and industry.
It is certainly fair to say that workers in the field require access to current state-ofthe-
art data, and the Analytical Profiles series has always provided information of
the highest quality. For this reason, profiles of older compounds are being updated
whenever appropriate. The growth of the analytical methodology used to provide
the data in these profiles also continues at a phenomenal rate, with many of the
significant advances being chronicled in the Journal of Pharmaceutical and
Biomedical Analysis (JPBA). The close relationship between these flagship sources
of analytical information is evident in that the undersigned is an assistant editor for
JPBA, and that the North American editor of JPBA is a member of the editorial
board of the Analytical Profiles.
The series’ mission was expanded some time ago to include profiles of excipient
materials, reflecting that these materials require the full degree of scrutiny
historically associated with drug compounds. These highly detailed compilations of
excipient properties and analytical methods have been well received by workers in
the field, and such profiles will continue to be sought. In the present volume, the
series’ mission is further expanded to include a profile of a natural product which
has been used as a precursor material in the synthesis of new drug candidates. If this
information proves to be of interest to the pharmaceutical community, additional
chapters of this type will be developed.
As always, the success of the Analytical Profiles series will continue to be based on
the contributions of the chapter authors and on the quality of their work. A
complete list of available drug and excipient candidates is available from the editor.
We look forward to hearing from new and established authors and to working with
the pharmaceutical community on the Analytical Profiles of Drug Substances and
Excipients.
remains as important today as it was when the Analytical Profiles series was first
initiated. The compilation of concise summaries of physical and chemical data,
analytical methods, routes of compound preparation, degradation pathways, and the
like, is a vital function to both academia and industry.
It is certainly fair to say that workers in the field require access to current state-ofthe-
art data, and the Analytical Profiles series has always provided information of
the highest quality. For this reason, profiles of older compounds are being updated
whenever appropriate. The growth of the analytical methodology used to provide
the data in these profiles also continues at a phenomenal rate, with many of the
significant advances being chronicled in the Journal of Pharmaceutical and
Biomedical Analysis (JPBA). The close relationship between these flagship sources
of analytical information is evident in that the undersigned is an assistant editor for
JPBA, and that the North American editor of JPBA is a member of the editorial
board of the Analytical Profiles.
The series’ mission was expanded some time ago to include profiles of excipient
materials, reflecting that these materials require the full degree of scrutiny
historically associated with drug compounds. These highly detailed compilations of
excipient properties and analytical methods have been well received by workers in
the field, and such profiles will continue to be sought. In the present volume, the
series’ mission is further expanded to include a profile of a natural product which
has been used as a precursor material in the synthesis of new drug candidates. If this
information proves to be of interest to the pharmaceutical community, additional
chapters of this type will be developed.
As always, the success of the Analytical Profiles series will continue to be based on
the contributions of the chapter authors and on the quality of their work. A
complete list of available drug and excipient candidates is available from the editor.
We look forward to hearing from new and established authors and to working with
the pharmaceutical community on the Analytical Profiles of Drug Substances and
Excipients.
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