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Wednesday, March 17, 2010

Advances in Fischer-Tropsch Synthesis, Catalysts, and Catalysis

Advances in Fischer-Tropsch Synthesis, Catalysts, and Catalysis.
By B. H. Davis, Mario L. Occelli


  • Publisher: CRC Press
  • Number Of Pages: 424
  • Publication Date: 2009-11-10
  • ISBN-10 / ASIN: 1420062565
  • ISBN-13 / EAN: 9781420062564

Product Description:

Rising oil costs have stimulated significant interest in the Fischer-Tropsch synthesis (FTS) as a method for producing a synthetic petroleum substitute. Drawn from the proceedings at a symposium held during the 236th meeting of the American Society in Philadelphia in August 2008, Advances in Fischer-Tropsch Synthesis, Catalysts, and Catalysis explores the recent developments in Fischer-Tropsch technology, which holds great promise in the area of renewable resources.

Expert contributors explore a range of issues

The focuses on three main themes: catalyst preparation and activation, reaction mechanism, and process-related topics. A panel of expert contributors discusses synthesis of catalysts, nanomaterials, nitric oxide calcinations, the influence of carbon, catalytic performance issues, chelating agents, and Cu and alkali promoters. They also explore Co/silica catalysts, thermodynamic control, the Two Alpha model, co-feeding experiments, internal diffusion limitations, Fe-LTFT selectivity, and the effect of co-fed . Lastly, the book examines cross-flow filtration, kinetic studies, reduction of CO2 emissions, syncrude, and low-temperature water-gas shift.

Attaining the maximum catalytic activity and catalyst life

The themes explored in the book demonstrate that while the Fischer-Tropsch synthesis (FTS) has advanced in maturity, many issues remain concerning the preparation of increasingly active catalysts and the method of activation to attain the maximum catalytic activity and catalyst life. The book includes coverage of the structural features, their changes, and the application of increasingly sophisticated characterization techniques, shedding light on the reaction mechanism and providing a glimpse into the processes and reaction rates under realistic commercial process conditions.

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Teacher's Handbook of Chemistry

Publication: Chandni Chowk, Delhi Global Media, 2009.


Subject: Chemistry--Handbook

Pages: 250

eBook ISBN: 9789380168937

Contents

1. Place of Chemistry in Science
2. Programmed Teaching
3. The Background
4. Role of the Teacher
5. Methods of Teaching
6. Aims and Objects of Teaching
7. Teaching Aids
8. Role

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Chromatography of Aroma Compounds and Fragrances

Chromatography of Aroma Compounds and Fragrances.
By Tibor Cserháti

  • Publisher: Springer
  • Number Of Pages: 392
  • Publication Date: 2010-03-29
  • ISBN-10 / ASIN: 3642016553
  • ISBN-13 / EAN: 9783642016554


Product Description:

This is the only comprehensive survey of chromatographic methods for the analysis of aroma compounds and fragrances. A unique feature of the are the extensive tables with relevant data. This will help significantly to choose an appropriate method, and to compare its characteristics with that of other methods. Coverage of applications includes essential oils, as well as environmental samples. Tibor Cserháti is a recognized member of the separation science community with long-standing experience. He is author or coauthor of six books and more than 490 scientific papers.

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Asymmetric Organocatalysis

Asymmetric Organocatalysis (Topics in Current Chemistry, Volume 291)
By Benjamin List
  • Springer
  • Number Of Pages: 400
  • Publication Date: 2010-03-28
  • ISBN-10 / ASIN: 3642028144
  • ISBN-13 / EAN: 9783642028144
Product Description:
The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern research. The scope of coverage includes all areas of science including the interfaces with related disciplines such as biology, medicine and materials science.

The goal of each thematic volume is to give the non-specialist reader, whether at the university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience.

Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the procedures involved is often useful to the reader. The coverage should not be exhaustive in data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Discussion of possible future directions in the area is welcome. Review articles for the individual volumes are invited by the volume editors.

Chapters in this volume:
* Noncovalent Organocatalysis Based on Hydrogen Bonding: Elucidation of Reaction Paths by Computational Methods
* Enamine Catalysis
* Carbene Catalysts
* Brønsted Base Catalysts
* Chiral Ketone and Iminium Catalysts for Olefin Epoxidation
* Amine, Alcohol and Phosphine Catalysts for Acyl Transfer Reactions
* Secondary and Primary Amine Catalysts for Iminium Catalysis
* Lewis Acid Organocatalysts
* Chiral Brønsted Acids for Asymmetric Organocatalysis.

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Pharmaceutical Packaging Handbook

 by: Edward Bauer
en

Pharmaceutical Packaging Handbook
By EdwardBauer

· Publisher: Informa Healthcare

· Number Of Pages: 350

· Publication Date: 2009-03-24

· ISBN-10 / ASIN: 1587161516

· ISBN-13 / EAN: 9781587161513


Product Description:

A complete overview of the role that packaging plays in the development and delivery of pharmaceuticals and medical devices. Including a thorough examination of the industry in size and scope, this source gives an introduction drug dosage forms, vaccines, biologically produced products, and medical foods to the reader.

Pharmaceutical Packaging Handbook is the most complete and straightforward text on the market today and also lists information in an easy to follow fashion, making it a complete stand-alone reference for anyone working in the pharmaceutical industry.

Pharmaceutical Packaging Handbook:

discusses how packaging is designed and integrated into the product development cycle has an overview of the regulatory environment procedures provides the reader with a basic introduction into key aspects of navigating the regulations describing the materials used to package pharmaceuticals, including glass, metal, plastics, flexible films, rubbers and elastomers comments on some new hybrids used for packaging, with a short introduction to plastics, their makeup, and typical uses in packaging explores the processing techniques used with the materials to produce pharmaceutical containers and some of the strengths and weaknesses of the processes used for container fabrication introduces the reader to retort, aseptic, gas, and radiation sterilization of product discusses labeling and design for pharmaceuticals including how labels are produced, materials used, and production techniques

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Name Reactions: A Collection of Detailed Mechanisms and Synthetic Applications, 4th Edition

Name Reactions: A Collection of Detailed Mechanisms and Synthetic Applications, 4th Edition.
By Jie Jack Li


  • Number Of Pages: 621
  • Publication Date: 2009-09-10
  • ISBN-10 / ASIN: 3642010520
  • ISBN-13 / EAN: 9783642010521


Product Description:

The fourth edition is revolutionary in comparison to the previous three editions. The format change has doubled the space to accommodate at least two to three real case applications in synthesis for each name reaction. The references are updated to 2009. Several new name reactions and reagents are included to reflect the state-of-the-art of organic chemistry.

Unlike other on name reactions in organic chemistry, Name Reactions, A Collection of Detailed Reaction Mechanisms and Synthetic Applications focuses on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. Now with addition of many synthetic applications, it is not only an indispensable resource for senior undergraduate and graduate students for learning and exams, but also a good reference book for all organic chemists interested in name reactions.

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Saturday, February 20, 2010

Handbook of Phase Change: Boiling and Condensation


S. G. Kandlikar, "Handbook of Phase Change: Boiling and Condensation"
CRC | 1999-06-01 | ISBN: 1560326344 | 784 pages | PDF | 10,9 MB

Provides a comprehensive coverage of the basic phenomena. It contains twenty-five chapters which cover different aspects of boiling and condensation. First the specific topic or phenomenon is described, followed by a brief survey of previous work, a phenomenological model based on current understanding, and finally a set of recommended design equations or correlations. Detailed references are listed at the end of each chapter for further reading.

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Convective Boiling and Condensation


John G. Collier, John R. Thome, "Convective Boiling and Condensation"
Oxford University Press, USA | 1994-06-30 | ISBN: 0198562829 | 640 pages | PDF | 9,2 MB

On its original publication in 1973, this book was the first reference for engineers to fully present the science of boiling and condensation. It dealt especially with the problems of estimating heat transfer rates and pressure drops, with particular attention to the occurrence of boiling and condensation in the presence of forced flows within pipes. The new third edition covers recent advances and significantly extends coverage to flows over tube bundles, with extensive new treatment of two-phase heat transfer regarding refrigerants and petrochemicals. Many new problems have been added at the end of each chapter to enhance the book's use as a text in advanced courses on two-phase flow and heat transfer. The book is written primarily for design and development engineers in the chemical process, power generation, and refrigeration industries, and is meant to be an aid in the design of heat exchangers.

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Saturday, February 13, 2010

The Textbook of Pharmaceutical Medicine

The Textbook of Pharmaceutical Medicine.
By John P. Griffin

  • Publisher: BMJ Books / Wiley-Blackwell
  • Number Of Pages: 776
  • Publication Date: 2009-12-14
  • ISBN-10 / ASIN: 1405180358
  • ISBN-13 / EAN: 9781405180351
Product Description:

The Textbook of Pharmaceutical Medicine is a standard reference for all those working in pharmaceutical medicine and the recognised text for the UK Faculty of Pharmaceutical Medicine Diploma. This is a comprehensive volume covering the processes by which medicines are developed, tested and approved. Regulations for drug development in the UK, EU, USA, Australia and Japan are discussed, providing relevant information for drug approval in the main continents where new drugs are developed.

The chapters are written by leading academics, medical directors and lawyers, providing authoritative and in-depth information for trainees on the Faculty course, and for physicians working in the pharmaceutical industry. As well as thorough updating of the regulatory chapters, the 6th edition includes chapters on these vital new areas:

  • Paediatric regulation
  • Ethics
  • Due diligence and the pharmaceutical physician.
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Introduction to Modern Liquid Chromatography, Third Edition

Introduction to Modern Liquid Chromatography, Third Edition.
By Lloyd R. Snyder, Joseph J. Kirkland, John W. Dolan

  • Publisher: Wiley
  • Number Of Pages: 912
  • Publication Date: 2009-12-09
  • ISBN-10 / ASIN: 0470167548
  • ISBN-13 / EAN: 9780470167540
Product Description:

The latest edition of the authoritative reference to HPLC

High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples.

This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as:

  • The basis of HPLC separation and the general effects of different experimental conditions
  • Equipment and detection
  • The column—the "heart" of the HPLC system
  • Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques
  • Computer simulation, qualitative and quantitative analysis, and method validation and quality control
  • The separation of large molecules, including both biological and synthetic polymers
  • Chiral separations, preparative separations, and sample preparation
  • Systematic development of HPLC separations—new to this edition
  • Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms
Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.

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Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 1: Compressed Solid Products

Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 1: Compressed Solid Products.
By Sarfaraz K. Niazi

  • Publisher: Informa Healthcare
  • Number Of Pages: 648
  • Publication Date: 2009-09-21
  • ISBN-10 / ASIN: 1420081160
  • ISBN-13 / EAN: 9781420081169
Product Description:

The largest category of pharmaceutical formulations, comprising almost two-thirds of all dosage forms, compressed solids present some of the greatest challenges to formulation scientists. The first volume, Compressed Solid Products, tackles these challenges head on.

Highlights from Compressed Solid Products, Volume One include:

  • formulations for more than 200 of the most widely used drugs for all types of release profiles, offering formulators a rare opportunity to start with an optimal composition
  • the essentials of what you need to be aware of when establishing a manufacturing process based on the formulations presented
  • identification and inclusion of the most popular prescription products, a critical list for the selection of products.
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Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 2: Uncompressed Solid Products

Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 2: Uncompressed Solid Products.
By Sarfaraz K. Niazi

  • Publisher: Informa Healthcare
  • Number Of Pages: 392
  • Publication Date: 2009-09-21
  • ISBN-10 / ASIN: 1420081187
  • ISBN-13 / EAN: 9781420081183
Product Description:

Providing methodologies that can serve as a reference point for new formulations, the second volume covers uncompressed solids, which include formulations of powders, capsules, powders ready for reconstitution, and other similar products.

Highlights from Uncompressed Solid Products, Volume Two include:

  • the fundamental issues of good manufacturing practices
  • formulations for more than 400 pharmaceutical products, including currently approved products and innovative products such as small proteins, instantly liquifiable powders, and nanoparticles
  • access to US FDA guidelines, as well as all major guidelines around the world
  • identification and inclusion of the most often approved capsules and powders in the US.
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Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 3: Liquid Products

Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 3: Liquid Products.
By Sarfaraz K. Niazi

  • Publisher: Informa Healthcare
  • Number Of Pages: 400
  • Publication Date: 2009-09-21
  • ISBN-10 / ASIN: 1420081233
  • ISBN-13 / EAN: 9781420081237
Product Description:

While liquid drugs do not share the compression problems of solid dosage forms, the filling problems of powder dosage forms, or the consistency problems of semisolid dosage forms, they do have their own set of considerations in the formulation and manufacturing stages.

Highlights from Liquid Products, Volume Three include:

  • practical details involved in complying with the current good manufacturing practice requirements in liquid manufacturing
  • access to what an FDA auditor would be looking for during a liquid manufacturing audit
  • issues that may arise during a US FDA inspection
  • the protocols used for stability testing for new drugs and new dosage forms, drawn from the most current ICH guidelines.
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Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 4: Semisolid Products

Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 4: Semisolid Products.
By Sarfaraz K. Niazi
  • Publisher: Informa Healthcare
  • Number Of Pages: 376
  • Publication Date: 2009-09-21
  • ISBN-10 / ASIN: 1420081268
  • ISBN-13 / EAN: 9781420081268
Product Description:

The fourth volume in the series covers the techniques and technologies involved in the preparation of semisolid products such as ointments, creams, gels, suppositories, and special topical dosage forms. Drug manufacturers need a thorough understanding of the specific requirements that regulatory agencies impose on the formulation and efficacy determination of drugs contained in these formulations.

Highlights from Semisolid Products, Volume Four include:

  • coverage of over 350 formulations
  • valuable information on the difficult area of compliance
  • changes to approved new drug applications and abbreviated new drug applications
  • the evolving guidelines of ICH and when to conduct a regulatory review.
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Handbook of Pharmaceutical Manufacturing Formulations Series, Second Edition, Volume 5: Over-the-Counter Products

Handbook of Pharmaceutical Manufacturing Formulations Series, Second Edition, Volume 5: Over-the-Counter Products.
By Sarfaraz K. Niazi
  • Publisher: Informa Healthcare
  • Number Of Pages: 480
  • Publication Date: 2009-09-21
  • ISBN-10 / ASIN: 1420081284
  • ISBN-13 / EAN: 9781420081282
Product Description:

Over-the-Counter products comprise a special category of healthcare products. While these formulations have much in common with their prescription counterparts, they are presented in this series separately because of their development approach taken, labeling considerations required, and support available from suppliers of ingredients in designing these products.

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Highlights from Over-the-Counter Products, Volume Five include:

  • solids, liquids, and suspensions
  • practical advice on how to bring manufacturing practices into compliance with regulatory requirements
  • cGMP considerations in great detail
  • a large number of formulations of coatings of solid dosage forms.

Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 6: Sterile Products

Handbook of Pharmaceutical Manufacturing Formulations, Second Edition, Volume 6: Sterile Products.
By Sarfaraz K. Niazi

  • Publisher: Informa Healthcare
  • Number Of Pages: 464
  • Publication Date: 2009-09-21
  • ISBN-10 / ASIN: 1420081306
  • ISBN-13 / EAN: 9781420081305
Product Description:

No other area of regulatory compliance receives more attention and scrutiny by regulatory authorities than the regulation of sterile products, for obvious reasons. With the increasing number of potent products, particularly the new line of small protein products, joining the long list of proven sterile products, the technology of manufacturing sterile products has evolved into a very sophisticated industry.

Highlights from Sterile Products, Volume Six include:

  • formulations of sterile dosage forms, regulatory filing requirements of sterile preparations, and cGMP compliance, all of which are tied together in the final preparation of the CMC sections of regulatory applications
  • specifications of a manufacturing facility to manufacture compliant sterile products
  • NDA or aNDA filing requirements of sterile products
  • an alphabetical presentation of formulations of pharmaceutical products based on their generic names
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Compatibility of Pharmaceutical Solutions and Contact Materials: Safety Assessments of Extractables and Leachables for Pharmaceutical Products

Compatibility of Pharmaceutical Solutions and Contact Materials: Safety Assessments of Extractables and Leachables for Pharmaceutical Products.
By Dennis Jenke

  • Publisher: Wiley-Interscience
  • Number Of Pages: 379
  • Publication Date: 2009-06-02
  • ISBN-10 / ASIN: 0470281766
  • ISBN-13 / EAN: 9780470281765

Product Description
This book specifically addresses the safety aspects of compatibility for drugs and their delivery devices and containers. The author deals with issues such as how the leachables impact safety of a therapeutic product and, more importantly, how one ascertains the magnitude of the impact. The book examines the strategies and tactics for performing safety assessments for leachables and extractables and establishes the means for interpreting the results obtained from such assessments. It helps the pharmaceutical industry unify methodology for assessing leachables and extractables safety of drug packaging.
From the Back Cover Compatibility of Pharmaceutical Products and Contact Materials

Dennis Jenke

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Handbook of Pharmaceutical Manufacturing Formulations, Second Edition: (Six-Volume Set)

Handbook of Pharmaceutical Manufacturing Formulations, Second Edition: (Six-Volume Set).
By Sarfaraz K. Niazi

  • Publisher: Informa Healthcare
  • Number Of Pages: 2094
  • Publication Date: 2009-09-21
  • ISBN-10 / ASIN: 1420081063
  • ISBN-13 / EAN: 9781420081060

Product Description:

An authoritative and practical guide to the art and science of formulating drugs.

With thoroughly revised and expanded content, this Second Edition six-volume set compiles volumes from FDA New Drug Applications, patent applications, and other sources of generic and proprietary formulations to cover the broad spectrum of issues concerning drug manufacturing.

A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this set is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent.

As the largest reference on pharmaceutical formulations, this handbook also provides guidelines on how to file aNDAs in the shortest possible time, helping pharmaceutical companies to cut costs in the areas of pharmaceutical research and development.

Divided conveniently into two parts—regulatory and manufacturing guidelines, and formulations—each volume in the set covers:

  • cGMP compliance
  • pre-approval inspections
  • stability and bioequivalence testing
  • packaging commodity development
  • common difficulties in formulating drugs
  • changes to aNDAs
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Preclinical Drug Development, Second Edition (Drugs and the Pharmaceutical Sciences)

Preclinical Drug Development, Second Edition (Drugs and the Pharmaceutical Sciences).
By Mark Rogge, David R. Taft

  • Publisher: Informa Healthcare
  • Number Of Pages: 536
  • Publication Date: 2009-09-25
  • ISBN-10 / ASIN: 1420084720
  • ISBN-13 / EAN: 9781420084726

Product Description:

Preclinical Drug Development, Second Edition discusses the broad realm of preclinical drug development, ranging from assessment of pharmacology and toxicology to the industry trends and regulatory expectations and requirements that support clinical trials. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.

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