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Tuesday, February 14, 2012

The Psychology of Emotion: From Everyday Life to Theory Book

The Psychology of Emotion From Everyday Life to Theory

Publisher: Wiley | ISBN: 0471485675 | edition 2003 | PDF | 340 pages | 11,6 mb
‘It is late at night and you are sitting quietly. The neighbours are all away. Suddenly, there is a huge thump on the front door, a scream and then a deathly quiet…’
As emotion and emotional experience are a daily occurrence, they have always been key topics of study for psychologists. Now in its fifth edition, The Psychology of Emotion is a classic student text on the subject. This textbook offers a comprehensive guide to all the main theories and concepts of emotion, and relates these back to everyday life, using examples that everyone can identify with.
Written in an engaging, accessible style, this fully revised edition features:
* comprehensive overview and discussion of the main theories of emotion
* real-life examples to illustrate key concepts
* discussion topics
* chapter summaries

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Organic Mechanisms Reactions Stereochemistry and Synthesis

Publisher: Springer | ISBN 10: 3642036503 | 2010 | PDF | 856 pages | 9.6 MB
This English edition of a best-selling and award-winning German textbook Reaction Mechanisms: Organic Reactions · Stereochemistry · Modern Synthetic Methods is aimed at those who desire to learn organic chemistry through an approach that is facile to understand and easily committed to memory. Michael Harmata, Norman Rabjohn Distinguished Professor of Organic Chemistry (University of Missouri) surveyed the accuracy of the translation, made certain contributions, and above all adapted its rationalizations to those prevalent in the organic chemistry community in the English-speaking world.
Throughout the book fundamental and advanced reaction mechanisms are presented with meticulous precision. The systematic use of red "electron-pushing arrows" allows students to follow each transformation elementary step by elementary step. Mechanisms are not only presented in the traditional contexts of rate laws and substituent effects but, whenever possible, are illustrated using practical, useful and state-of-the-art reactions. The abundance of stereoselective reactions included in the treatise makes the reader familiar with key concepts of stereochemistry.
The fundamental topics of the book address the needs of upper-level undergraduate students, while its advanced sections are intended for graduate-level audiences. Accordingly, this book is an essential learning tool for students and a unique addition to the reference desk of practicing organic chemists, who as life-long learners desire to keep abreast of both fundamental and applied aspects of our science. In addition, it will well serve ambitious students in chemistry-related fields such as biochemistry, medicinal chemistry and pharmaceutical chemistry.

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Green Chemical Reactions Book

Green Chemical Reactions AvaxHome

Springer; 1 edition | May 27, 2008 | ISBN-10: 1402084587 | 232 pages | PDF | 3.5 Mb
Green Chemistry is an inventive science based on fundamental research towards the development of new sustainable chemical processes. There is a great need to create a new type of chemistry focused on a new production system, in order to prepare the younger generation to get a greener future.
The globalization pushes the chemistry community to adopt ethical issues. In this prospect Green Chemistry can achieve the approval of the society by teaching students to be confident in science and at the same time by convincing people that it is possible to attain technological development with respect and care for the environment we live in. This is why it is of foremost importance that education and fundamental research remain strictly connected, so that democracy and development can grow and progress side by side.

Book author:

ISBN: 1402084587
Publisher:
Release Date:

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Modern Oxidation Methods, 2 edition Book

Modern Oxidation Methods 2 edition AvaxHome

W..ey-VC.H | 2010 | ISBN: 3527323201 | 481 pages | PDF | 5,6 MB
While rust is an unwanted oxidation reaction, there are also many other useful oxidation reactions that are extremely important and number among the most commonly used reactions in the chemical industry.
This completely revised, updated second edition now includes additional sections on industrial oxidation and biochemical oxidation.
Edited by one of the world leaders in the field, high-quality contributions cover every important aspect from classical to green chemistry methods:
Recent Developments in Metal-catalyzed Dihydroxylation of Alkenes
Transition Metal-Catalyzed Epoxidation of Alkenes
Organocatalytic Oxidation. Ketone-Catalyzed Asymmetric Epoxidation of Alkenes and Synthetic Applications
Catalytic Oxidations with Hydrogen Peroxide in Fluorinated Alcohol Solvents
Modern Oxidation of Alcohols using Environmentally Benign Oxidants
Aerobic Oxidations and Related Reactions Catalyzed by N-Hydro xyphthalimide
Ruthenium-Catalyzed Oxidation for Organic Synthesis
Selective Oxidation of Amines and Sulfides
Liquid Phase Oxidation Reactions Catalyzed by Polyoxometalates
Oxidation of Carbonyl Compounds
Manganese-Catalyzed Oxidation with Hydrogen Peroxide
Biooxidation with Cytochrome P450 Monooxygenases
By providing an overview of this vast topic, the book represents an unparalleled aid for organic, catalytic and biochemists working in the field.

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Monday, February 13, 2012

Synthesis and characterization of piperazine containing a typical antipsychotic drug substances and their related compounds(SOURCE:SHODHGANGA)

Title: 
Synthesis and characterization of piperazine containing a typical antipsychotic drug substances and their related compounds

Researcher: 
Thatipalli, Poorna Chander

Guide(s): 
Ramesh Kumar

Keywords: 
Chemistry
Drug Substances

Issue Date: 
5-Aug-2011

University: 
Jawaharlal Nehru Technological University

Award Date: 
2010

Pagination: 
xxix, 232p.

URI: 
http://hdl.handle.net/10603/2184

Appears in Departments:
Faculty of Chemistry

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05_acknowledgements.pdf
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07_table of contents.pdf
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DOWNLOAD Ph.D THESIS(ANALYTICAL CHEMISTRY)(SOURCE:SHODH GANGA)

Title: 
Studies on development of analytical method, validation and applications for some drugs

Researcher: 
Kher, Govind JGuide(s): Joshi, H S Keywords: Chemistry, Drugs Issue Date: 18-Aug-2011 University: Saurashtra University Award Date: 2011 Pagination: 
293p.

URI: 
http://hdl.handle.net/10603/2282

Appears in Departments:
Department of Chemistry

01_title.pdf
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02_declaration and certificate.pdf
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03_dedication.pdf
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04_acknowledgements.pdf
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05_contents.pdf
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06_synopsis.pdf
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10_part d.pdf
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title: 
Development and validation of analytical methods for the determination of related components in Pharmaceutical

Researcher: 
Madhavi, A

Guide(s): 
Suryanarayana, M V and Naidu, A

Keywords: 
Chemistry, Pharmaceutical Compounds, Chromatography technique, Organic Impurities, Drug Products, Drug substances

Issue Date: 
25-Aug-2011

University: 
Jawaharlal Nehru Technological University

Award Date: 
2010

Abstract:

Pagination: 
vii, 490p.

URI: 
http://hdl.handle.net/10603/2370

Appears in Departments:
Department of Chemistry

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04_preface.pdf
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06_abbrevations.pdf
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07_chapter 1.pdf
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08_chapter 2.pdf
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14_chapter 8.pdf
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Title: 
Synthesis, characterisation and antibacterial activity of organic molecules

Researcher: 
Chavda, Mukesh M

Guide(s): 
Upadhyay, Jatin J

Keywords: 
Chemistry, Organic Molecules

Issue Date: 
19-Aug-2011

University: 
Saurashtra University

Award Date: 
2010

Pagination: 
216p.

URI: 
http://hdl.handle.net/10603/2287

Appears in Departments:
Department of Chemistry

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04_abstract.pdf
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05_general introduction.pdf
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06_contents.pdf
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07_part 1.pdf
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08_part 1 reference.pdf
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09_part 2.pdf
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10_part 2 reference.pdf
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11_part 3.pdf
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Chemistery II

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Saturday, February 11, 2012

A-Z CHEMICAL ENGINEERING SOFTWARES

LinkA-Z CHEMICAL ENGINEERING SOFTWARES



This post contain a link which contain all chemical engineering software A-Z.

https://plus.google.com/u/0/photos/109083611906864350653/albums/5682577287968608865

An act to streamline, harmonize US patent law


On September 16, 2011, the US President Barack Obama signed the Leahy-Smith America Invents Act – enacting it into law that is widely perceived as a reform to foster innovation and stimulate US economic growth by streamlining, harmonizing the US patent process. The new law will speed up the patent process that will help applicants and entrepreneurs bringing their inventions to market sooner, creating jobs and new business avenues. This reform is proposed to give a boost to American companies and inventors who suffered costly delays and unnecessary litigation, and to focus instead on innovation and job creation.

The new law have several effective dates for various provisions, some changes coming in effect immediately whereas other changes will not be implemented until 2012 and 2013. Some of the key highlights of American Invents Act include:
Section 3
First Inventor to File
Amends 35 USC § 100 to reform the US patent system by adopting a first-to-file system instead of a first-to-invent system, bringing the US in conformity with the rest of the world in determining priority of invention based on the earliest date a patent application was filed with a patent office. There is a limited one-year grace period related to public disclosures made by the inventor.

Derivative proceedings
Amends 35 USC § 135 to replace interference proceedings with “derivative proceedings” to determine whether an inventor of first-filed patent application derived the claimed subject matter without authorization from an invention named in a later filed application. This reform will eliminate long-standing interference proceedings. A petition for derivative proceeding will only be allowed if it is filed within a limited one-year period beginning on the date of the first publication of a claim in the earlier filed application.

Conditions for patentability; novelty
Amends 35 USC § 102 to redefine the scope of prior art as anything patented, published, on sale, or in public use before filing, or any patent application filed by another before the effective filing date of the claimed invention. This reform will now broaden the scope of on-sale or public use outside the US, bringing the US in conformity with practice of other jurisdictions such as EU and India. This reform will now allow US examiners to take into account traditional/indigenous knowledge whether in written or oral form as prior art in determining novelty of the invention.

Conditions for patentability; non-obvious subject matter
Amends 35 USC § 103 to consider obviousness as of the effective filing date of the claimed subject-matter rather than at the time invention was made.

Amendments made to section 3 will come in effect 18 months after the date of enactment, i.e. March 16, 2013.
Section 4
Inventor’s oath or declaration
Amends 35 USC § 115 to permit applicants to make a “substitute statement” instead of an inventor’s oath when an inventor is deceased, under legal incapacity, or cannot be found or reached after diligent effort.

Filing by other than inventor
Amends 35 USC § 118 to allow applicants to file the application for patent when inventors has assigned or are under the obligation to assign the invention, bringing the US in conformity with the rest of the world in permitting applicants to directly file patent application on behalf of inventors.

Amendments made to section 4 will come in effect 1 year after the date of enactment, i.e. September 16, 2012.
Section 5
Defense to infringement based on prior commercial use
Amends 35 USC § 273 to expand “the prior user” defense to infringement to all patents rather than restricting only to business method patents. The prior user have the burden of showing a prior use of the claimed invention more than a year before the priority date of the claimed invention. Even if a prior use is kept confidential it will be a valid defense to infringement. The prior use defense is not available in case where the invention was owned by or under obligation of assignment to a university or technology transfer organization at the time invention was made.
An act to streamline, harmonize US patent law - II
Section 6
Inter partes review
Amends 35 USC § 311 to replace inter partes re-examination with “inter partes review” allowing third party to challenge validity or scope of an issued patent only on a ground that is permissible under 35 USC § 102 and 103. The review must be filed within nine months after grant or reissuance of patent or after the grant of termination of post-grant review. Prior art submissions are limited to patents and printed literature.

Post grant review
Enacts 35 USC § 321 to allow third party (petitioner) to institute a post-grant review for an issued patent. The review must be filed within nine months after grant or reissuance of patent. This reform will permit third party to challenge the validity or scope of patent based on any ground of patentability and prior art submission is not limited to patents and printed literature. Importantly, in the case of both post-grant review and inter partes review proceeding, the third party will be estopped from raising similar invalidity arguments in subsequent USPTO or the International Trade Commission (ITC) or litigation proceedings that were raised or reasonably could have been raised during the review.

This reform will now allow the US to have post-grant opposition procedure similar to Europe and India. Amendments made to section 6 will come in effect 1-year after the date of enactment, i.e. September 16, 2012 and will be applicable to any patent issued before or after the effective date.

Section 7
Patent Trial and Appeal Board
Amends 35 USC § 6 to existing Board of Patent Appeals and Interferences with newly formed “Patent trial and Appeal Board” to hear appeals and conduct derivation, inter partes review and post-grant review proceedings. The Patent Trial and Appeal Board will be having a panel of at least three members.

Appeal to Court of Appeals for the Federal Circuit
Amends 35 USC § 141 to permit either party to appeal the Patent Trial and Appeal Board adverse decision only to the US Court of Appeals for the Federal Circuit.

Amendments made to section 7 will come in effect 1-year after the date of enactment, i.e. September 16, 2012 and will be applicable to proceedings commenced on or after the effective date.

Section 8
Preissuance submission by third parties
Amends 35 USC § 122 to permit third party to submit, for consideration and inclusion in the record of a patent application, any patent, published patent application, or other printed publication of potential relevance to the examination of the application, if such submission is made in writing within six months of publication of the application.

Amendments made to section 8 will come in effect 1-year after the date of enactment, i.e. September 16, 2012 and will be applicable to any patent application filed before or after the effective date.

Section 9
Venue
Amends 35 USC § 32, 145, 146, 154(b)(4)(A) and 293 to shift default venue from United States District Court of Columbia to “United States District Court for the Eastern District of Virginia.”

This amendment is in effect immediately and will apply to any civil action commenced on or after the effective date.

Section 10
Micro entity defined
Enacts 35 USC § 123 to include a new class of inventor “micro-entity” which has filed no more than four applications, and has gross income below a designated level without having transferred ownership interest in the application to an entity with gross income exceeding such limit. This provision is in effect immediately.

Friday, February 10, 2012

Molegro Virtual Docker



Molegro Virtual Docker v4.2.0 | 13.9 MB

Molegro Virtual Docker is an integrated platform for predicting protein - ligand interactions. Molegro Virtual Docker handles all aspects of the docking process from preparation of the molecules to determination of the potential binding sites of the target protein, and prediction of the binding modes of the ligands. Molegro Virtual Docker offers high-quality docking based on a novel optimization technique combined with a user interface experience focusing on usability and productivity. The Molegro Virtual Docker (MVD) has been shown to yield higher docking accuracy than other state-of-the-art docking products (MVD: 87%, Glide: 82%, Surflex: 75%, FlexX: 58%).

Molegro Data Modeller offers different types of data modelling:
Multiple Linear Regression models simple linear relations between data, and is fast and efficient.
Partial Least Squares reduces the dimensionality of the data set before creating a model. Suitable for data sets with many independent variables.
Neural Networks are able to model highly non-linear relations.
Support Vector Machines are also able to model complex relations and tend to be less prone to overfitting than Neural Networks.
K-Nearest-Neighbors for simple classification.

Different regression types.
Feature Selection and Cross-Validation
Feature selection is easy to set up in the regression wizard: different schemes can be chosen (Forward, Backward, and Hill Climber selection) and be combined with different model selection criteria (Bayes Information Criterion or cross validated R^2). Different descriptor rankings can be employed when searching the descriptors.

Cross-validation is just as easy. Cross-validate using a specified number of random folds, by using Leave-One-Out, or by manually creating folds.

Visualization
The different visualization types are highly interactive. Selections in the spreadsheet are directly shown in the plots and vice versa. It is also possible to apply different user-defined coloring schemes and apply jitter (add artificial noise to the data plots).

It is possible to visualize high-dimensional data. Using the built-in Spring-mass Map model, high-dimensional data can be projected onto 2D or 3D

Chemistry
Molegro Data Modeller supports chemical data: MDM understands SMILES and SDF files and can create 2D depictions of molecules directly in the spreadsheet or in the 2D plotter.

Clustering
Molegro Data Modeller offers different kinds of clustering: K-means clustering and threshold-based clustering (both very efficient), and a density-based clustering scheme (which is able to capture more complex cluster shapes).

Principal Component Analysis (PCA).
Principal Component Analysis is a method for reducing the dimensionality of a dataset. A new set of principal components is created using linear combinations of the original descriptors. The number of descriptors is then reduced by only keeping the descriptors contributing most to the variance.

Algebraic Data Transformations.

It is possible to work with algebraic transformations directly on columns: for instance, "New Activity = log(Act) + Beta^2" will create a new column based on the expression.

Outlier Detection
Molegro Data Modeller provides two methods for locating abnormal data:
A quartile based method which checks how far away a data point is from the 25th and 75th percentile. This method examines each descriptor individually.
A density-based method which calculates a local density for each data point. Data points with a low density are far away from other data points and could be outliers.

Advanced Subset Creation
Molegro Data Modeller offers a grid-based method for creating a diverse subset of a dataset. It is possible to create grids in an arbitrary number of dimensions, and if working with 2D and 3D grids they can be visualized directly in the data plotters.

Other Features
Scrambling (shuffling) of columns and "replace with random values" for performing y-Randomization.
Data preparation: scaling, normalization, repair of missing values.
Statistical measures: Pearson and Spearman correlation, Confusion matrices, F-measures, and many others.
Correlation Matrix.
Cross-term generation.
Custom Data Views and Grid Molecule Depictions.
Similarity Browser (Euclidean, Manhattan, Cosine, and Tanimoto measures).
Gnuplot export (for creating and customizing publishing quality plots).
Online help and automatic check for updates.

Home Page - http://www.molegro.com/mmv-product.php

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