Scientist-At-Work: May 2010

Sunday, May 30, 2010

Martindale: The Complete Drug Reference, 36th Edition

By Sean C. Sweetman

Publisher: Pharmaceutical Press

Number Of Pages: 3694

Publication Date: 2009-03-16

ISBN-10 / ASIN: 0853698406

ISBN-13 / EAN: 9780853698401

Product Description:

This book provides reliable, unbiased and evaluated information on drugs and medicines used throughout the world. Each new drug licensed for use has its own potential benefits and adverse effects, and its own profile for dosage, administration and indications. Furthermore, manufacturers make regular changes to existing drug names and formulations, which can affect their interactions and safe usage. Health professionals require the correct answers and need to have confidence in the drugs information they use – but with medicines evolving at this rate, how can they be sure their knowledge is up to date? "Martindale" contains up to date information about more than 5,800 substances. Each and every entry is reviewed by our pharmaceutical editors to ensure health professionals have the most current data. Formulations change. Definitions change. Names change. But you can always trust "Martindale".

Free download Links

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http://hotfile.com/dl/14087998/10839a6/_Martindale36.rar.html

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Chemstations CHEMCAD 6.1.4.3059

Chemstations CHEMCAD 6.1.4.3059 | 174 MB

CHEMCAD is an integrated suite of intuitive chemical process engineering software.
CHEMCAD's scalability allows users to purchase add-ons and features as needed for their specific industry and processes. This results in ultimate flexibility and affordability.

The CHEMCAD suite of products includes:

CC-STEADY STATE

Chemical process simulation software that includes libraries of chemical components, thermodynamic methods, and unit operations to allow steady-state simulation of continuous chemical processes from lab scale to full scale.

Ideal for: Users who want to design processes, or rate existing processes, in steady state.

CC-DYNAMICS

Process simulation software that takes steady-state simulations to the next level of fidelity to allow dynamic analysis of flowsheets. The possibilities are endless: operability check-out, PID loop tuning, operator training, even online process control and soft sensor functionality.

Ideal for: Users who want to design or rate dynamic processes.

CC-THERM

Heat exchanger design and rating software available as an add-on or standalone program. CC-THERM makes use of multiple international standards for design and materials to make sizing a heat exchanger faster and more accurate. The program covers shell-and-tube, plate-and-frame, air-cooled, and double-pipe exchangers. Rigorous designs are based on CHEMCAD's foundation of physical property and phase equilibria data.

Ideal for: Users who want to design or vet a design by a vendor of a heat exchanger (single unit at a time), and those who want to rate existing exchangers in new service or perform "what if" calculations.

CC-SAFETY NET

Piping and safety relief network simulation software that is a subset of CC-STEADY STATE (all of CC-SAFETY NET's features are included in CC-STEADY STATE). This program allows rigorous analysis of any piping. It combines the latest in two-phase relief device calculation, rigorous pressure drop calculation, rigorous physical property calculation, and rigorous phase equilibrium calculation to deliver fast, accurate answers.

Ideal for: Users who need to design or rate piping networks or safety relief devices/systems.

CC-FLASH

Physical properties and phase equilibria calculation software that is a subset of the CHEMCAD suite (all of the CHEMCAD suite products include CC-FLASH capabilities). This program allows rigorous calculation of physical properties and phase equilibria (VLE, LLE, VLLE) for pure components and mixtures.

Ideal for: Users who need physical property and phase equilibrium data, as well as users who need property prediction and regression.

DOWNLOAD LINK:
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Tuesday, May 25, 2010

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Computer/Electrical eBooks: http://www.nuneworld.net/?cat=11

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Collection of Power Plant Ebooks :

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English Language Ebooks

Safety Assessment for Chemical Processes by Jorg Steinbach

John Wiley & Sons | 1998-12-23 | ISBN: 352728852X | 305 pages | PDF | 13.8 Mb

This book combines the author's experience of 15 years of research in the field of chemical safety and 10 years in the chemical industry. It provides newcomers with an easy access to the field and helps practitioners in the chemical industry to answer all questions concerning their daily work with hazardous materials or potentially dangerous chemical plants. The investigation of risks, and preventive measures to be taken to minimize the probability of an accident, as well as its consequences are explained.

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Chemical Drawing Tools

Chemical Draw

ACD/ChemSketch 12.0	advanced chemical drawing tool
Symyx Draw 3.2	chemically intelligent drawing package
Marvin 5.2.04	Java based chemical drawing tool
ACD/Structure Drawing Applet 1.30	a complete structure drawing, editing, and visualization tool
ChemFormatter 1.2.5	add-in program for Microsoft Office. ChemFormatter automatically applies font styles in a chemical document.
Chemistry 4-D Draw Demo	chemistry program combining the most advanced technologies in structure drawing.
ChemDraw Ultra 12.0 Trial	the software used by scientists to draw structures
JChemPaint 2.5.7	an editor for 2D molecular structures.
TinkerCell 1.1.04	A free and open-source computer-aided design (CAD) software for synthetic biology.
WinDrawChem 1.6.2	Freeware two-dimensional molecule drawing program.
ChemDoodle 2.0.2	A fully functional chemical drawing application
ChemicPen 2.6	Easy to use software for drawing 2D chemical formulae and reactions.
WinPLT 7.1	A program for drawing chemical structures.
BKChem 0.13.0	Free, portable, and open-source structure drawing program.
KegDraw 0.19b	Java application for drawing compound and glycan structures.

Sunday, May 23, 2010

NMR Spectroscopy in Pharmaceutical Analysis

NMR Spectroscopy in Pharmaceutical Analysis.

By Iwona Wawer, Bernd Diehl, Ulrike Holzgrabe

Publisher: Elsevier Science

Number Of Pages: 528

Publication Date: 2008-10-10

ISBN-10 / ASIN: 0444531734

ISBN-13 / EAN: 9780444531735

Binding: Hardcover

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. , impurity profiling and assay, qNMR can be utilized.

Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis.

Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.

combines theory, techniques, and concrete applicationsall of which closely resemble the laboratory experience

considers international pharmacopoeias, addressing the concern for licensing

features the work of academics and researchers, appealing to a broad readership.

Free download Links:

http://www.megaupload.com/?d=SVDJRL0Q

http://ifile.it/juq6hn8/174955___tnmr_spectro_pharmana.zip

Jobs in the Drug Industry: A Career Guide for Chemists

Jobs in the Drug Industry: A Career Guide for Chemists.

By Richard J. Friary

Publisher: Academic Press

Number Of Pages: 364

Publication Date: 2000-04-15

ISBN-10 / ASIN: 0122676459

ISBN-13 / EAN: 9780122676451

Binding: Paperback

This book is intended to help newly graduated chemists, particularly organic chemists, at all levels from bachelors to post-doctorates, find careers in the North American pharmaceutical industry. It will serve as a practical, detailed guiedbook for job seekers as well a reference work for faculty advisers, research supervisors, development officers, employment agents, and personnel managers in the industry. The book gathers in a single volume the fundamentals of getting an industrial job as a medicinal or process chemist, and covers all aspects of a chemist’s job–scientific, financial, and managerial–within a pharmaceutical/biotechnology company. Other scientists looking for jobs as analytical or physical chemists and even biochemists and biologists will find the book useful. The valuable appendix is a unique compendium of 365 commercial, governmental, or non-profit institutions that comprise the North American pharmaceutical industry.

Key Features

* Learn How To:

* Discover the 12 permanent, big-pharma jobs for B.S. chemists

* Use the 500 company index to locate potential employers

* Track pharma openings with 190 corporate and chemist-specific job banks

* Add industry veterans to your employment network

* Find the 50 companies offering paid summer internships to students

* Include the one resume item that wins interviews for B.S. and M.S. chemists

* Express a knowledgeable preference for drug discovery or development

* Research over 360 drug companies through their Web sites.

Free download Links:

http://ifile.it/vzbn7xu/0122676459.zip

Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products

Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products.

By Margriet M. W. B. Hendricks, Jan H. De Boer, Age K. Smilde, Margriet M. W. B. Hendriks, Jan H. Boer

Publisher: Elsevier Publishing Company

Number Of Pages: 360

Publication Date: 1996-12-01

ISBN-10 / ASIN: 0444897097

ISBN-13 / EAN: 9780444897091

Binding: Hardcover

Hardbound. In analytical chemistry and pharmaceutical technology attention is increasingly focussed on improving the quality of methods and products. This book aims at fostering the awareness of the potential of existing mathematical and statistical methods to improve this quality. It provides procedures and ideas on how to make a product or a method less sensitive to small variations in influencing factors. Major issues covered are robustness and stability improvement and ruggedness testing. General strategies and a theoretical introduction to these methods are described, and thorough overviews of methods used in both application areas and descriptions of practical applications are given.

Features of this book:

â ¢ Gives a good overview of mathematical and statistical methods used in two application areas, i.e. pharmaceuticaltechnology and analytical chemistry

â ¢ Illustrates the different approaches available to attain robustness.

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Friday, May 14, 2010

Heterocyclic Chemistry.

By John A. Joule, Keith Mills

Publisher: Wiley-Blackwell
Number Of Pages: 640
Publication Date: 2010-06-15
ISBN-10 / ASIN: 1405133007
ISBN-13 / EAN: 9781405133005

Product Description:

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide.

Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry.

The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry.

Fully updated and expanded to reflect important 21^st century advances, the fifth edition of this classic text includes the following innovations:

Extensive use of colour to highlight changes in structure and bonding during reactions
Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine
New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context

Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

DOWNLOAD LINK:

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Friday, May 7, 2010

Answer Keys: The Art of Writing Reasonable Organic Reaction Mechanisms

Answer Keys: The Art of Writing Reasonable Organic Reaction Mechanisms.

By Robert Grossman

Springer
Number Of Pages: 331
Publication Date: 1998-11-01
ISBN-10 / ASIN: 0387985409
ISBN-13 / EAN: 9780387985404

Product Description:

A first year graduate textbook for advanced organic or special topics in organic chemistry courses. The author uses a number of devices to help students understand the material and there are extensive problem sets at the end of all of the chapters. In addition, this will be a useful reference for students who do not take a formal course.

Answer Kyes only, freely available at :

http://www.springer.com/chemistry/organic+chemistry/book/978-0-387-95468-4

http://www.chem.uky.edu/research/grossman/textbook.html

DOWNLOAD LINK:

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Green Chemistry in the Pharmaceutical Industry

By Peter Dunn, Andrew Wells, Michael T. Williams

Publisher: Wiley-VCH
Number Of Pages: 388
Publication Date: 2010-05-10
ISBN-10 / ASIN: 3527324186
ISBN-13 / EAN: 9783527324187

Product Description:

Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.

DOWNLOAD LINK:

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http://filefactory.com/file/b170dd1/n/Green_Chemistry_in_the_Pharmaceutical_Industry.rar

Thursday, May 6, 2010

Chiral Amine Synthesis: Methods, Developments and Applications

Chiral Amine Synthesis: Methods, Developments and Applications.

By Thomas C. Nugent

Publisher: Wiley-VCH
Number Of Pages: 520
Publication Date: 2010-04-19
ISBN-10 / ASIN: 3527325093
ISBN-13 / EAN: 9783527325092

Product Description:

This first comprehensive presentation of this hot and important topic compiles the most up-to-date methods for chiral amine synthesis. The international list of authors reads like a "Who's Who" of the subject, providing a large array of highly practical information concentrated into the useful and essential methods.

Following an introductory chapter devoted to helping readers quickly determine which strategies to choose for their investigation, this handbook and ready reference focuses on the examination of methods that are reliable and simultaneously efficient for the synthesis of structurally diverse aliphatic and aromatic chiral amines. Modern methods and applications found in (pharmaceutical) industry are also covered.

DOWNLOAD LINK:

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Organic Mechanisms: Reactions, Stereochemistry and Synthesis

Organic Mechanisms: Reactions, Stereochemistry and Synthesis.

By Reinhard Bruckner

Publisher: Springer
Number Of Pages: 856
Publication Date: 2010-03-23
ISBN-10 / ASIN: 3642036503
ISBN-13 / EAN: 9783642036507

Product Description:

This English edition of a best-selling and award-winning German textbook Reaction Mechanisms: Organic Reactions · Stereochemistry · Modern Synthetic Methods is aimed at those who desire to learn organic chemistry through an approach that is facile to understand and easily committed to memory. Michael Harmata, Norman Rabjohn Distinguished Professor of Organic Chemistry (University of Missouri) surveyed the accuracy of the made certain contributions, and above all adapted its rationalizations to those prevalent in the organic chemistry community in the English-speaking world.

Throughout the book fundamental and advanced reaction mechanisms are presented with meticulous precision. The systematic use of red "pushing arrows" allows students to follow each transformation elementary step by elementary step. Mechanisms are not only presented in the traditional contexts of rate laws and substituent effects but, whenever possible, are illustrated using practical, useful and state-of-the-art reactions. The abundance of stereoselective reactions included in the treatise makes the reader familiar with key concepts of stereochemistry.

The fundamental topics of the book address the needs of upper-level undergraduate students, while its advanced sections are intended for graduate-level audiences. Accordingly, this book is an essential learning tool for students and a unique addition to the reference desk of practicing organic chemists, who as life-long learners desire to keep abreast of both fundamental and applied aspects of our science. In addition, it will well serve ambitious students in chemistry-related fields such as biochemistry, medicinal chemistry and pharmaceutical chemistry.

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Sunday, May 30, 2010

Martindale: The Complete Drug Reference, 36th Edition

Chemstations CHEMCAD 6.1.4.3059

Tuesday, May 25, 2010

Tons of Free Ebooks, links, & forums.

English Language Ebooks

English Language Ebooks

Safety Assessment for Chemical Processes by Jorg Steinbach

Chemical Drawing Tools

Chemical Draw

Sunday, May 23, 2010

NMR Spectroscopy in Pharmaceutical Analysis

Jobs in the Drug Industry: A Career Guide for Chemists

Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products

Friday, May 14, 2010

Heterocyclic Chemistry.

Friday, May 7, 2010

Answer Keys: The Art of Writing Reasonable Organic Reaction Mechanisms

Green Chemistry in the Pharmaceutical Industry

Thursday, May 6, 2010

Chiral Amine Synthesis: Methods, Developments and Applications

Organic Mechanisms: Reactions, Stereochemistry and Synthesis