Tuesday, September 30, 2008

Profiles of Drug Substances, Excipients and Related Methodology

Book Description:

Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic.

The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

* Presents comprehensive reviews covering all aspects of drug development and formulation of drugs
* Now encompassing critical review chapters
* Meets the information needs of the drug development community.

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Volume:33

http://rapidshare.com/files/87190761/Pro_Drug_Sub_E_Vol33.zip

Volume:31

http://rapidshare.com/files/101822099/Profiles_of_Drug_Substances__Excipients_and_Related_Methodology__Volume_31__Profiles_of_D.rar

Volume:30

http://rapidshare.com/files/77514691/Profiles_of_Drug_Substances_Excipients_and_Related_Methodology_.rar

Volume:27

http://rapidshare.com/files/136435803/tanaprodrug_Subs_exp_vol27.zip

Volume:28

http://rapidshare.com/files/101812843/Analytical_Profiles_of_Drug_Substances_and_Excipients__Volume_28__Profiles_of_Drug_Substances__Excip

Volume:29

http://rapidshare.com/files/81555455/Analytical_Profiles_of_Drug_Substances_and_Excipients__Volume_29.rar

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Monday, September 29, 2008

Toxicology of Solvents.

Toxicology of Solvents.
By M. McParland, N. Bates
  • Publisher: Rapra Technology Ltd
  • Number Of Pages: 400
  • Publication Date: 2001-12
  • ISBN-10 / ASIN: 1859572960
  • ISBN-13 / EAN: 9781859572962
  • Binding: Hardcover
About the Author:

The Medical Toxicology Unit at Guy’s and St Thomas’ Hospital in London is one of the largest specialist toxicology units in the world, providing information about poisoning to health professionals via a 24 hour telephone service. The National Poisons Information Service (London) has been operating for over 30 years and is one of the busiest in the world, handling the majority of the 200,000 calls made each year in the UK.

All contributors are Poisons Information Specialists at the Medical Toxicology Unit, with extensive experience in advising the UK National Health Service on the consequences of chemical accidents and chemical exposures.

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http://rapidshare.com/files/148651759/1859572960.rar

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Analysis of Plastics

Analysis of Plastics (Rapra Review Reports)
By M, J Forrest
  • Publisher: Smithers Rapra Technology
  • Number Of Pages: 160
  • Publication Date: 2002-05-01
  • ISBN-10 / ASIN: 1859573339
  • ISBN-13 / EAN: 9781859573334
  • Binding: Paperback.
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http://rapidshare.com/files/148649122/1859573339.rar
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Pharmaceutical Process Engineering

Pharmaceutical Process Engineering (Drugs and the Pharmaceutical Sciences)
By Anthony J. Hickey
  • Publisher: Informa HealthCare
  • Number Of Pages: 286
  • Publication Date: 2001-03-15
  • ISBN-10 / ASIN: 0824702980
  • ISBN-13 / EAN: 9780824702984
  • Binding: Hardcover
Product Description:

Summarizing fundamental engineering principles and operations critical to converting bulk pharmaceutical products into patient-ready and appropriate drug delivery dosage forms, Pharmaceutical Process Engineering facilitates comprehensive understanding of the practical aspects of drug production in an accessible, step-by-step format. It provides a pharmaceutical perspective on unit operations that improves communication among diverse professionals in the field-from pharmaceutical researchers to chemical and industrial engineers-and fully covers the relationship of pharmaceutical development to the application of key concepts and major unit operations in pharmaceutical engineering.

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http://rapidshare.com/files/18809247/PPE.rar.html

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Advances in Crystal Growth Inhibition Technologies

Advances in Crystal Growth Inhibition Technologies
By Zahid Amjad
  • Publisher: Springer
  • Number Of Pages: 278
  • Publication Date: 2000-12
  • ISBN-10 / ASIN: 0306464993
  • ISBN-13 / EAN: 9780306464997
  • Binding: Hardcover
Product Description:

In this book, academic researchers and technologists will find important information on the interaction of polymeric and non-polymeric inhibitors with a variety of scale forming crystals such as calcium phosphates, calcium carbonate, calcium oxalates, barium sulfate, calcium pyrophosphates, and calcium phosphonates. Moreover, the book delivers information to plant managers and formulators who would like to broaden and deepen their knowledge about processes involved in precipitation of sparingly soluble salts and learn more about the inhibitory aspects of various commercially available materials. Furthermore, experienced researchers will obtain fruitful and inspiring ideas from the easily accessible information about overlapping research areas, which will promote discoveries of new inhibitors (synthetic and/or natural) for the currently unmet challenges.

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http://rapidshare.com/files/7749348/AdvancesInCrystalGrowthInhibitionTechnologies.rar

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Hansen Solubility Parameters: A User's Handbook, Second Edition

Hansen Solubility Parameters: A User's Handbook, Second Edition
By Charles M. Hansen
  • Publisher: CRC
  • Number Of Pages: 544
  • Publication Date: 2007-06-15
  • ISBN-10 / ASIN: 0849372488
  • ISBN-13 / EAN: 9780849372483
  • Binding: Hardcover
Product Description:

Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including polymers, inorganic salts, and biological materials.

To update his groundbreaking handbook with the latest advances and perspectives, Charles M. Hansen has invited five renowned experts to share their work, theories, and practical applications involving HSPs. New discussions include a new statistical thermodynamics approach for confirming existing HSPs and how they fit into other thermodynamic theories for polymer solutions. Entirely new chapters examine the prediction of environmental stress cracking as well as absorption and diffusion in polymers. Highlighting recent findings on interactions with DNA, the treatment of biological materials also includesskin tissue, proteins, natural fibers, and cholesterol. The book also covers the latest applications of HSPs, such as ozone-safe “designer” solvents, protective clothing, drug delivery systems, and petroleum applications.

Presenting a comprehensive survey of the theoretical and practical aspects of HSPs, Hansen Solubility Parameters, Second Edition concludes with a detailed discussion on the necessary research, future directions, and potential applications for which HSPs can provide a useful means of prediction in areas such as biological materials, controlled release applications, nanotechnology, and self-assembly.

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Practical Process Research & Development

Practical Process Research & Development
By Neal G. Anderson
  • Publisher: Academic Press
  • Number Of Pages: 354
  • Publication Date: 2000-04-15
  • ISBN-10 / ASIN: 0120594757
  • ISBN-13 / EAN: 9780120594757
  • Binding: Hardcover
Product Description:

This book will provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine
chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key
compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are
identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and
academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent,
and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students.

* Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules"
* Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more
* Includes over 100 tips for rapid process development
* Presents guidelines for implementing and troubleshooting processes.

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http://rapidshare.com/files/59056383/Practical-Process-Research_Development.rar


Posted by Kmist at 10:44 PM 0 comments Links to this post

Chiral Separation Techniques (Third Edition)

  • Publisher: 2007 Wiley-VCH Verlag GmbH & Co. KGaA
  • Number Of Pages: 619
  • Publication Date: 20 Sep 2007
  • Sales Rank:
  • ISBN / ASIN: Print ISBN: 9783527315093 Online ISBN: 9783527611737
  • EAN:
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Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.

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http://rapidshare.com/files/64288637/CST3.rar

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Pharmaceutical Production Facilities: Design and Applications

Pharmaceutical Production Facilities: Design and Applications (Taylor & Francis Series in Pharmaceutical Sciences)
By Graham Cole
  • Publisher: Informa HealthCare
  • Number Of Pages: 342
  • Publication Date: 1998-02-11
  • ISBN-10 / ASIN: 0748404384
  • ISBN-13 / EAN: 9780748404384
  • Binding: Hardcover
Product Description:

Pharmaceutical Production Facilities: Design and Applications considers the concepts and constraints that have to be considered in the design of small, medium and large scale production plants. The layout, along with the flow of materials and personnel through facilities are considered with reference to ensuring compliance with current good manufacturing practice. The book explains how clean rooms have developed, and how recent regulations affect their design. The latest concepts for reducing contamination levels from the operator and the product are discussed. It assess current changes in standards and quality control and makes suggestions for the "ideal production environment" to enable standards to be validated to current standards.

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http://rapidshare.com/files/147707299/0748404384.zip

Posted by Kmist at 10:33 PM 0 comments Links to this post

Bioassay Techniques for Drug Development

Bioassay Techniques for Drug Development
By Atta-ur Rahman, MI Choudhary, W Thompson
  • Publisher: Informa HealthCare
  • Number Of Pages: 232
  • Publication Date: 2001-09-14
  • ISBN-10 / ASIN: 9058230511
  • ISBN-13 / EAN: 9789058230515
  • Binding: Hardcover
Product Description:

The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The contents detail a number of enzyme-based assays, cell-based functional bioassays and receptor radioligand binding assays along with detailed descriptions of each type. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry or pharmacology.

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http://rapidshare.com/files/148356796/9058230511.zip

Posted by Kmist at 10:31 PM 0 comments Links to this post

Pharmaceutical Product Strategy: Using Dynamic Modeling for Effective Brand Planning

  • Publisher: Informa HealthCare
  • Number Of Pages: 328
  • Publication Date: 2004-12-28
  • ISBN-10 / ASIN: 0849327296
  • ISBN-13 / EAN: 9780849327292
  • Binding: Hardcover
Product Description:

Borrowing time-tested Dynamic Modeling (DM) techniques from engineering, the authors illustrate the concept and resulting power of the DM methodology in pharmaceutical product development and brand management. The book examines issues surrounding utilization of information, consistency of assumptions, and the need for approaches that integrate the institutional knowledge of various functional areas as well as leverage the vast amount of secondary data available in the pharmaceutical industry. The authors detail how the DM approach facilitates the brand planning process in a systematic and accessible way. Issues of patient flow dynamics, physician adoption and prescribing patterns, as well as evaluation frameworks for specific treatment regimens are thoroughly examined. A later chapter details the extension of the DM framework to issues of pipeline portfolio management using agent-based modeling techniques and uncertainty formulations.

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http://rapidshare.com/files/149010719/0849327296.rar



Posted by Kmist at 10:29 PM 0 comments Links to this post

Immunoassay: A Practical Guide

Immunoassay: A Practical Guide
(Ellis Horwood Series in Pharmaceutical Technology)
By Brian Law
  • Publisher: CRC
  • Number Of Pages: 222
  • Publication Date: 1996-10-04
  • ISBN-10 / ASIN: 0748405607
  • ISBN-13 / EAN: 9780748405602
  • Binding: Library Binding
Product Description:

Immunoassay development is a multidisciplinary activity involving a wide range of skills possessed by few laboratories. This presentation of tried and tested methods should enable scientists and researchers in the pharmaceutical and related industries to more rapidly and effectively develop immunoassays upon which their work is becoming heavily dependent.; Important methods are included for preparing Lapten-protein conjugates and raising the necessary antibodies, concentrating on polyclonal sera, as well as methods for the synthesis of radio and enzyme labelled tracers. Particular attention is paid to the requirements of the regulatory authorities such as the FDA (Food and Drug Administration) with respect to assay validation. Further chapters deal with assay development and optimization, curve fitting and quality control procedures.

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Posted by Kmist at 10:26 PM 0 comments Links to this post

Toxicology of industrial compounds

Toxicology of industrial compounds
By H. Thomas
  • Publisher: CRC
  • Number Of Pages: 448
  • Publication Date: 1995-12-01
  • ISBN-10 / ASIN: 074840239X
  • ISBN-13 / EAN: 9780748402397
  • Binding: Library Binding
Product Description:

A large number of chemical compunds are constantly being introduced and produced, both to assist and ease modern human life. Among these chemicals, industrial compounds represent a particular fraction of chemicals which are not intended for use in biological systems, but to which humans may be accidently exposed, whether in the workplace, by product application, or via the environment. Industrial chemicals, as opposed to pharmaceuticals and agrochemicals, are in many cases subjected only to a very basic examination of handling safety, and may lack further toxicity testing. This implies that essentially nothing is known about their bioavailability, metabolism, excretion and toxicological properties, unless problems arise.; Covering the investigation of industrial chemicals, this book focuses on their individual structure, biological fate, potential toxicity to mammals and the molecular mechanisms possibly underlying their adverse effects by highlighting the use and significance of experimental toxicology. Special emphasis is placed on mechanistic aspects in the safety assessment of industrial compounds, in addition to current regulatory and legal considerations.

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http://rapidshare.com/files/148896263/074840239X.zip

Posted by Kmist at 10:24 PM 0 comments Links to this post

Handbook of Aqueous Solubility Data

Handbook of Aqueous Solubility Data
By Samuel H. Yalkowsky, Yan He
  • Publisher: CRC
  • Number Of Pages: 1512
  • Publication Date: 2003-03-26
  • ISBN-10 / ASIN: 0849315328
  • ISBN-13 / EAN: 9780849315329
  • Binding: Hardcover
Product Description:

Over the years researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until now, this information has been scattered throughout the literature. Containing over 16,000 solubility data points for more than 4,000 organic compounds, Handbook of Aqueous Solubility Data provides an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, agricultural, industrial, and energy related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CAS Registry Number, melting point, and boiling point if available. Each entry has a five-point evaluation score for the quality of the reporting of the data, along with the full citation, and comments from the authors when necessary. The user-friendly format gives a clear depiction of each piece of solubility data with enough information to estimate its validity. Handbook of Aqueous Solubility Data gives you a portable, accessible resource for solubility data of numerous compounds and a single system for the evaluation of the data supplied.

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http://rapidshare.com/files/149093245/0849315328.zip

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Saturday, September 27, 2008

Chemical Properties Handbook: Physical, Thermodynamics, Engironmental Transport, Safety & Health Related Properties for Organic & Inorganic Chemical

Chemical Properties Handbook: Physical, Thermodynamics, Engironmental Transport, Safety & Health Related Properties for Organic & Inorganic Chemical
By Carl Yaws
  • Publisher: McGraw-Hill Professional
  • Number Of Pages: 784
  • Publication Date: 1998-10-01
  • ISBN-10 / ASIN: 0070734011
  • ISBN-13 / EAN: 9780070734012
  • Binding: Hardcover
Product Description:

Necessary data that's often hard to find or difficult to calculate, all in one place, in easy-access format. That's what this Handbook provides to scientific, engineering, and environmental professionals, and students, who seek information on how chemicals will behave at different temperatures and under different conditions. Covering both organic and inorganic substances, and providing both experimental values and estimated values based on methods developed by the author and other noted experts, this book can save countless hours of searching for the right source or performing complicated calculations. Useful for hundreds of on-the-job information requirements, this much-needed Handbook makes it easy to obtain critical values for temperature and pressure for design or operation of compressors and turbines; find heat capacity data for heat exchangers; accurately design and safely operate vaporizers and condensers with precise information on enthalpy of vaporization; size vaporizer/condenser storage vessels with density data; determine the heating and cooling requirements of reactors with values for the enthalpy of formation; determine chemical equilibria for reactions using Gibbs’ energy of formation; design and operate effective stripping operations for water pollutant removal using water solubility data and Henry’s Law Constant; find needed adsorption capacities of activated carbon for cleaning air of various pollutants; use soil sorption coefficient for agricultural applications; solve problems for fluid flow of gases and liquids using viscosity data; use thermal conductivity data for heat transfer applications; use lower and upper explosion limits in air, flock point and autoignition temperature for safety in designs and operations; use threshold limit value (ACGIH), permissible exposure limit (OSHA) and recommended exposure limit (NIOSH) to design facilities while safeguarding health; use thermal expansion coefficient data to design relief systems; and find thousands of other time-saving uses.

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The Art of Problem Solving in Organic Chemistry

The Art of Problem Solving in Organic Chemistry
By Miguel E. Alonso
  • Publisher: Wiley-Interscience
  • Number Of Pages: 336
  • Publication Date: 1987-01
  • ISBN-10 / ASIN: 0471847844
  • ISBN-13 / EAN: 9780471847847
  • Binding: Hardcover
Product Description:

For students of advanced organic chemistry, this text develops problem-solving skills using fifty-six challenging, organic chemistry problems covering a wide variety of chemical systems. Concentrates on necessary and fundamental concepts in the introductory chapters. Valuable not only as a study guide and source of interesting problems, but also as an illustration of reactions and phenomena of general interest.

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http://rapidshare.com/files/105815752/the_art_of_problem_solving_in_organic_chemistry_-_m._alonso__1987__ww.pdf

Posted by Kmist at 1:30 PM 0 comments Links to this post

Design of Experiments in Chemical Engineering: A Practical Guide

Design of Experiments in Chemical Engineering: A Practical Guide
By Zivorad R. Lazic
  • Publisher: Wiley-VCH
  • Number Of Pages: 620
  • Publication Date: 2005-01-04
  • ISBN-10 / ASIN: 3527311424
  • ISBN-13 / EAN: 9783527311422
  • Binding: Hardcover

Product Description:

While existing books related to DOE are focused either on process or mixture factors or analyze specific tools from DOE science, this text is structured both horizontally and vertically, covering the three most common objectives of any experimental research:

  • screening designs
  • mathematical modeling, and
  • optimization

Written in a simple and lively manner and backed by current chemical product studies from all around the world, the book elucidates basic concepts of statistical methods, experiment design and optimization techniques as applied to chemistry and chemical engineering. Throughout, the focus is on unifying the theory and methodology of optimization with well-known statistical and experimental methods.

The author draws on his own experience in research and development, resulting in a work that will assist students, scientists and engineers in using the concepts covered here in seeking optimum conditions for a chemical system or process.
With 441 tables, 250 diagrams, as well as 200 examples drawn from current chemical product studies, this is an invaluable and convenient source of information for all those involved in process optimization.

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http://rapidshare.com/files/115693900/_2__DESIGN_OF_EXPERIMENTS_IN_CHEMICAL_ENGINEERING.pdf


Posted by Kmist at 1:28 PM 0 comments Links to this post

Handbook of Chemical Reactor Design, Optimization, and Scaleup

Handbook of Chemical Reactor Design, Optimization, and Scaleup
By Bruce Nauman
  • Publisher: McGraw-Hill Professional
  • Number Of Pages: 600
  • Publication Date: 2001-09-26
  • ISBN-10 / ASIN: 0071377530
  • ISBN-13 / EAN: 9780071377539
  • Binding: Hardcover
Product Description:

Black, gold foil-enhanced frame holds an 8 1/2 x 11 certificate. Built-in hook and easel allows wall or desktop display. Features black book bound edges and a clear acetate window to protect the award. Includes one sheet of 24 lb. ivory parchment paper.

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Modern Spectroscopy

Modern Spectroscopy
By J. Michael Hollas
  • Publisher: Wiley
  • Number Of Pages: 480
  • Publication Date: 2004-01-16
  • ISBN-10 / ASIN: 0470844167
  • ISBN-13 / EAN: 9780470844168
  • Binding: Paperback
Product Description:

The latest edition of this highly acclaimed title introduces the reader to a wide range of spectroscopies, and includes both the background theory and applications to structure determination and chemical analysis. It covers rotational, vibrational, electronic, photoelectron and Auger spectroscopy, as well as EXAFs and the theory of lasers and laser spectroscopy.

  • A revised and updated edition of a successful, clearly written book
  • Includes the latest developments in modern laser techniques, such as cavity ring-down spectroscopy and femtosecond lasers
  • Provides numerous worked examples, calculations and questions at the end of chapters.
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Vogel's Textbook of Practical Organic Chemistry (5th Edition)

Vogel's Textbook of Practical Organic Chemistry (5th Edition)
By A.I. Vogel, A.R. Tatchell, B.S. Furnis, A.J. Hannaford, P.W.G. Smith
  • Publisher: Prentice Hall
  • Number Of Pages: 1552
  • Publication Date: 1996-02-19
  • ISBN-10 / ASIN: 0582462363
  • ISBN-13 / EAN: 9780582462366
  • Binding: Hardcover
Product Description:

Most widely used, established and respected reference manual for the organic chemistry laboratory. Incorporates new reactions and techniques now available to the organic chemist.

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Mirror
type: RAR
size: 12.9 MB
VogelOrgChem.rar
RAR archive password: "gigapedia.org"
original filename: Vogel's Textbook of Practical Organic Chemistry 5th Ed. (Furnis B.S. et all, Longman 1989)
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Lange's Handbook of Chemistry

Lange's Handbook of Chemistry
By John A. Dean
  • Publisher: McGraw-Hill Professional
  • Number Of Pages: 1424
  • Publication Date: 1998-10-30
  • ISBN-10 / ASIN: 0070163847
  • ISBN-13 / EAN: 9780070163843
  • Binding: Hardcover
Product Description:

Revered as the standard reference for chemists for more than 60 years, this new edition of Lange's brings chemistry professionals, students, and anyone interested in science an enormous compilation of facts, data, tabular material, and experimental findings in every area of chemistry. Included in this massive compendium are listings of the properties of approximately 4,000 organic and 1,400 inorganic compounds. The 15th Edition includes new material on separation methods and analytical chemistry; statistical methods; polymers; rubbers, fats, oils, and waxes; new inorganic compounds; IUPAC nomenclature of organic compounds; updated lists of physical and chemical symbols; definitions and abbreviations; new tables, charts, and illustrations; with SI units used throughout (conversion tables supplied). The American Technical Technologists' Events magaine said of the last edition of this book, "Bargains are rare in the publication arena but this book represents one ... it is just overflowing with useful information that is available at your beck and call."

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Synthetic Nitrogen Products: A Practical Guide to the Products and Processes

Synthetic Nitrogen Products: A Practical Guide to the Products and Processes
By Gary Maxwell
  • Publisher: Springer
  • Number Of Pages: 388
  • Publication Date: 2004-05-19
  • ISBN-10 / ASIN: 0306482258
  • ISBN-13 / EAN: 9780306482250
  • Binding: Hardcover
Book Description:

This book provides a comprehensive description of 1) products that are made from or that contain nitrogen, 2) the processes that produce these products and 3) the markets that consume these products. The goal has been to present an abundance of information in one book so that the reader will find the maximum amount of useful information in one place.
The first four chapters provide basic information about nitrogen and nitrogen products and processes. Chapters 5 through 20 provide detailed descriptions of various nitrogen or nitrogen-containing products. The material is presented in a standardized format that should make this book easy to use and helpful to all readers. A wide variety of readers in countries around the world should find the book useful - from students to professors, to technical professionals to business marketing personnel.

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Friday, September 26, 2008

Thermal Analysis of Pharmaceuticals

Thermal Analysis of Pharmaceuticals
By Duncan Q.M. Craig, Mike Reading
  • Publisher: CRC
  • Number Of Pages: 416
  • Publication Date: 2006-12-21
  • ISBN-10 / ASIN: 0824758145
  • ISBN-13 / EAN: 9780824758141
  • Binding: Hardcover
Product Description:

As a result of the Process Analytical Technologies (PAT) initiative launched by the U.S. Food and Drug Administration (FDA), analytical development is receiving more attention within the pharmaceutical industry. Illustrating the importance of analytical methodologies, Thermal Analysis of Pharmaceuticals presents reliable and versatile characterization tools for the successful development of pharmaceutical products. It draws attention to the most widely applicable methods and demonstrates how to interpret the associated data.

The book opens with the first three chapters devoted to differential scanning calorimetry (DSC), the most commonly used thermal method. These chapters cover the principles, optimal use, and pharmaceutical applications of the method. Subsequent chapters explore modulated temperature DSC, thermogravimetric analysis, thermal microscopy, microcalorimetry, high sensitivity DSC, dynamic mechanical analysis, and thermally stimulated current, all of which have attracted great interest within the pharmaceutical field. The chapters include theoretical background, measurement optimization, and pharmaceutical applications of each technique.

Exploring important techniques for characterizing the physical structure and properties of pharmaceutical materials, Thermal Analysis of Pharmaceuticals achieves an ideal balance in the depth, relevance, and accessibility of topics presented. The book provides an excellent overview of this key area in pharmaceutical development.

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Posted by Kmist at 10:50 PM 0 comments Links to this post

Asymmetric Phase Transfer Catalysis

Asymmetric Phase Transfer Catalysis
By Keiji Maruoka
  • Publisher: Wiley-VCH
  • Number Of Pages: 228
  • Publication Date: 2008-04-18
  • ISBN-10 / ASIN: 3527318429
  • ISBN-13 / EAN: 9783527318421
  • Binding: Hardcover

Product Description:

Edited by the leading expert on the topic, this is the first book to present the latest developments in this exciting field. Alongside the theoretical aspects, the top contributors provide practical protocols to give readers additional important information otherwise unavailable.
A must for every synthetic chemist in academia and industry.

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Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes

  • Publisher: Elsevier Science
  • Number Of Pages: 532
  • Publication Date: 2007-05-07
  • ISBN-10 / ASIN: 0444527109
  • ISBN-13 / EAN: 9780444527103
  • Binding: Hardcover

Product Description:

Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes stems from the experience of the EC funded project DEMETRA. This project combined institutes involved in the regulatory process of pesticides, industries of the sector and scientists to develop and offer original software for the prediction of ecotoxicity of pesticides. Then to be used within the dossier preparation for pesticide registration. The basis of this book is more than three-years of research activities, discussions, studies and successful models. This experience represents a useful example not only for the case of pesticides, but also for the prediction of ecotoxicity and toxicity in general.

QSAR is used to link a given property of a chemical compound with some features related to its structure. The theoretical toxicological, chemical and information technology aspects will be treated considering the regulatory issues. Innovative hybrid systems will be described, for the toxicity prediction of pesticides and related compounds, directly useful for pesticide evaluation within the Dossier preparation for pesticide registration. Five endpoints will also be discussed, addressing issues as standardisation, verification, validation, accessibility, reproducibility.

The driving force for Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes is that all the issues of concern for end-users are analysed, discussed and solutions proposed further. An innovative feature is that, in order to offer powerful QSAR models, the book discusses and reports on integrated QSAR models, combined into a unique hybrid system.

* Assesses the needs of regulators for pesticide approval and how these needs affect QSAR models
* Combines theoretical discussion with practical examples, including five worked examples of hybrid systems
* Refers to original software available through the internet.

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Re-Evaluation of Some Organic Chemicals: Hydrazine & Hydrogen Peroxide

vol71imageyx6.jpg

Re-Evaluation of Some Organic Chemicals: Hydrazine & Hydrogen Peroxide (IARC Monographs on the Evaluation of Carcinogenic Risks to H)
By International Agency for Research on Cancer

  • Publisher: World Health Organization
  • Number Of Pages: 1586
  • Publication Date: 1999-12
  • ISBN-10 / ASIN: 9283212711
  • ISBN-13 / EAN: 9789283212713
  • Binding: Paperback

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

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Volume 71 (1999)
Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide.

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Ionic Liquids in Synthesis

Ionic Liquids in Synthesis (Green Chemistry (Wiley)(2 vol. set)
By Peter Wasserscheid, Thomas Welton
  • Publisher: Wiley-VCH
  • Number Of Pages: 776
  • Publication Date: 2007-12-21
  • ISBN-10 / ASIN: 3527312390
  • ISBN-13 / EAN: 9783527312399
  • Binding: Hardcover
Product Description:

The second, completely revised and enlarged edition of what has become the standard reference work in this fascinating field brings together the latest developments, supplemented by numerous practical tips, providing those working in both research and industry with an indispensable source of information. New contributions have been added, to reflect the fact that industrial processes are already established, and ionic liquids are now commercially available.
A must for everyone working in the field.

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Stereoselective Synthesis: Workbench Edition - Houben-weyl, Methods of Organic Chemistry

Stereoselective Synthesis: Workbench Edition - Houben-weyl, Methods of Organic Chemistry
By J. Houben, Theodor Weyl
  • Publisher: Thieme Medical Publishers
  • Number Of Pages:
  • Publication Date: 1997-01
  • ISBN-10 / ASIN: 0865776741
  • ISBN-13 / EAN: 9780865776746
  • Binding: Hardcover.
All 6 volumes merged in a 7000 pages long pdf file.
A must-have for all synthetic organic-chemists.

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Introduction to Mass Spectrometry

Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation
By J. Throck Watson, O. David Sparkman

Publisher: Wiley
Number Of Pages: 862
Publication Date: 2007-12-04
ISBN-10 / ASIN: 0470516348
ISBN-13 / EAN: 9780470516348
Binding: Hardcover

Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references.


This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry.

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Chromatography of Natural, Treated and Waste Waters

Chromatography of Natural, Treated and Waste Waters
By T R Crompton


Publisher: Taylor & Francis
Number Of Pages: 800
Publication Date: 2003-06-24
ISBN-10 / ASIN: 0415280044
ISBN-13 / EAN: 9780415280044
Binding: Hardcover

Chromatography of Natural, Treated and Waste Waters is the first book to bring together information of a range of chromatographic techniques in all types of water,from precipitation to sewage effluents. Organic and inorganic compounds, cations, anions and elements are all discussed. Particular attention is paid to multi compound analysis of water, and the analysis of minute traces of pollutants. Gas chromatography, high performance liquid chromatography and mass spectrometry are included, and this book is well referenced and easy to use.

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Developing the Leader Within You [Audio book]

Developing the Leader Within You [Audio book] -- John C. Maxwell (Author)
PUB: Thomas Nelson | English | 2004 | ISBN 0785260331 | WMA | 20 MB | 2h 15min
Few of us are natural-born leaders, according to John C. Maxwell, author of Developing the Leader Within You. Fortunately though, "the traits that are the raw material of leadership can be acquired," he promises. "Link them up with desire and nothing can keep you from becoming a leader. This book will supply the leadership principles. You must supply the desire." True to his words, Maxwell offers a detailed and inspiring primer on becoming a leader.

Book Description
After examining the differences between leadership styles, Maxwell outlines principles for inspiring, motivating, and influencing others. These principles can be used in any organization to foster integrity and self-discipline and bring a positive change.

Developing the Leader Within You also allows readers to examine how to be effective in the highest calling of leadership by understanding the five characteristics that set "leader managers" apart from "run-of-the-mill managers."

In this John Maxwell classic, he shows readers how to develop the vision, value, influence, and motivation required of successful leaders.
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Part 1
Part 2
Part 3

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Determination of Organic Compounds in Natural and Treated Waters

Determination of Organic Compounds in Natural and Treated Waters

By T R Crompton

Publisher: Taylor & Francis
Number Of Pages: 928
Publication Date: 1999-11-30
ISBN-10 / ASIN: 0419243607
ISBN-13 / EAN: 9780419243601
Binding: Library Binding


This book draws together and systemizes the vast body of information available on the occurrence and determination of organic substances, providing a comprehensive description of organic compounds in all types of non-saline and saline natural and treated waters. This book is an essential reference for analytical chemists working in industry in the water utilities, those working in government and non-government organizations and regulatory agencies, chemical companies producing aqueous effluents, and for environmental and analytical consultants.

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Instant Notes in Organic Chemistry

Instant Notes in Organic Chemistry (Instant Notes Series)
By Graham Patrick
  • Publisher: BIOS Scientific Publ
  • Number Of Pages: 328
  • Publication Date: 2004-03-10
  • ISBN-10 / ASIN: 1859962645
  • ISBN-13 / EAN: 9781859962640
  • Binding: Paperback
Product Description:

Instant Notes titles focus on core information and are designed to help undergraduate students come to grips with a subject quickly and easily.

Instant Notes in Organic Chemistry, 2/e concentrates entirely on the basics of the subject without going into exhaustive detail or repetitive examples. This is a student-friendly textbook and will help students understand the subject and encourage easy learning by focusing on the essentials of organic chemistry.

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Wednesday, September 24, 2008

Stop Faking It! Chemistry Basics

Stop Faking It! Chemistry Basics
By William C. Robertson

Publisher: NSTA Press
Number Of Pages: 112
Publication Date: 2007-01-01
ISBN-10 / ASIN: 0873552393
ISBN-13 / EAN: 9780873552394
Binding: Paperback

Best-selling author Bill Robertson takes a fresh approach to chemistry fundamentals by helping you understand them from the ground up. Instead of hounding you to memorize the characteristics of atoms and the periodic table, Chemistry Basics will help you see those characteristics as a natural consequence of our understanding of

Posted by Kmist at 10:24 PM 0 comments Links to this post

Instant Notes in Analytical Chemistry (Instant Notes)

Instant Notes in Analytical Chemistry (Instant Notes)

By D. Kealey

Publisher: BIOS Scientific Publ
Number Of Pages: 352
Publication Date: 2002-06-30
ISBN-10 / ASIN: 1859961894
ISBN-13 / EAN: 9781859961896
Binding: Paperback

Instant Notes titles focus on core information and are designed to help undergraduate students come to grips with a subject quickly and easily.

Instant Notes in Analytical Chemistry provides students with a thorough comprehension of analytical chemistry and its applications. This book supports the learning of principles and practice of analytical procedures. It also contains analytical techniques commonly used in laboratories today.

http://rapidshare.com/files/146203179/1859961894.zip

Posted by Kmist at 10:20 PM 0 comments Links to this post

Guidelines for Process Safety Documentation

Guidelines for Process Safety Documentation

By Center for Chemical Process Safety (CCPS)

Publisher: Wiley-AIChE
Number Of Pages: 386
Publication Date: 1995-04-15
ISBN-10 / ASIN: 0816906254
ISBN-13 / EAN: 9780816906253
Binding: Hardcover

The process industry has developed integrated process safety management programs to reduce or eliminate incidents and major consequences, such as injury, loss of life, property damage, environmental harm, and business interruption. Good documentation practices are a crucial part of retaining past knowledge and experience, and avoiding relearning old lessons. Following an introduction, which offers examples of how proper documentation might have prevented major explosions and serious incidents, the 21 sections in this book clearly present aims, goals, and methodology in all areas of documentation. The text contains examples of dozens of needed forms, lists of relevant industry organizations, sources for software, references, OSHA regulations, sample plans, and more.

http://rapidshare.com/files/146088503/Guidelines_Process_Safety_Documentation.rar

Posted by Kmist at 10:13 PM 0 comments Links to this post

Statistical Treatment of Analytical Data

Zeev Alfassi “Statistical Treatment of Analytical Data"
Blackwell | 2004-12-20 | ISBN: 084932436X | 266 pages | PDF | 1,2 MB

Rapidshare Mirror

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Tuesday, September 23, 2008

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
By Harmata.

 Publisher: Academic Press Number Of Pages: 134 Publication Date: 2005-10-03 ISBN-10 / ASIN: 012450289X ISBN-13 / EAN: 9780124502895 Binding: Paperback

Product Description:

A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

* Presents state-of-the-art developments in organic synthesis
* Provides insight and offers new perspective to problem-solving
* Written by leading experts in the field. http://rapidshare.com/files/140560829/STR.TAC.ORG.SYN.VOL.6.rar
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NMR Spectroscopy in Drug Development and Analysis

NMR Spectroscopy in Drug Development and Analysis
By Ulrike Holzgrabe, Iwona Wawer, Bernd Diehl, B Diehl
  • Publisher: Wiley-VCH
  • Number Of Pages: 299
  • Publication Date: 1999-10-15
  • ISBN-10 / ASIN: 3527300929
  • ISBN-13 / EAN: 9783527300921
  • Binding: Hardcover
Product Description:

Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis.
This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition of polymer excipients, the characterization of isomeric drug mixtures, the complexity of drugs with small-size components or ions, and the behavior of drugs in acid and basic solution. In addition, NMR spectroscopy and especially the hyphenated technique with HPLC is shown to be a powerful tool to measure a drug and its metabolites in various body fluids. The solid state NMR technique can give information on the structure, especially the conformation of drugs and excipients in drug formulations. Recently, SAR by NMR, introduced by Fesik, impressively demonstrated the potential of NMR spectroscopy in drug development and in the characterization of the interaction between large molecules and ligands. The complexation between proteins, lipids and cyclodextrins with drugs is described. Finally, NMR imaging (MRI and MRS) can be used to characterize the liberation of drugs from a drug formulation. Furthermore, the distribution of substances in plants, in animals, in tissues and in humans can be visualized by imaging.
In short, this book covers all aspects of drug analysis.

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Guidelines for Investigating Chemical Process Incidents

Guidelines for Investigating Chemical Process Incidents
By Center for Chemical Process Safety (CCPS)
  • Publisher: Wiley-AIChE
  • Number Of Pages: 452
  • Publication Date: 2003-03-15
  • ISBN-10 / ASIN: 0816908974
  • ISBN-13 / EAN: 9780816908974
  • Binding: Hardcover
Book Description:

This book provides a valuable reference tool for technical and management personnel who lead or are a part of incident investigation teams. This second edition focuses on investigating process-related incidents with real or potential catastrophic consequences. It presents on-the-job information, techniques, and examples that support successful investigations. The methodologies, tools, and techniques described in this book can also be applied when investigating other types of events such as reliability, quality, occupational health, and safety incidents. The accompanying CD-ROM contains the text of the book for portability as well as additional supporting tools for on-site reference and trouble shooting.

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Posted by Kmist at 9:40 PM 0 comments Links to this post

Plant Guidelines for Technical Management of Chemical Process Safety

by American Institute of Chemical Engineers

Plant Guidelines for Technical Management of Chemical Process Safety
By American Institute of Chemical Engineers
  • Publisher: American Institute of Chemical Engineers
  • Number Of Pages: 382
  • Publication Date: 1991-06
  • ISBN-10 / ASIN: 0816904995
  • ISBN-13 / EAN: 9780816904990
  • Binding: Hardcover.

http://rapidshare.com/files/78871439/PGTM0816904995.rar

Posted by Kmist at 9:38 PM 0 comments Links to this post

Guidelines for Chemical Reactivity Evaluation and Application to Process Design

Guidelines for Chemical Reactivity Evaluation and Application to Process Design
By Center for Chemical Process Safety (CCPS)
  • Publisher: Wiley-AIChE
  • Number Of Pages: 210
  • Publication Date: 1995-04-15
  • ISBN-10 / ASIN: 0816904790
  • ISBN-13 / EAN: 9780816904792
  • Binding: Hardcover
Product Description:

Drawn from international sources, this book provides principles and strategies for the evaluation of chemical reactions, and for using this information in process design and management. A useful resource for engineers who design, start-up, operate, and manage chemical and petrochemical plants, the book places special emphasis on the use of state-of-the-art technology in theory, testing methods, and applications in design and operations.

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Sunday, September 21, 2008

Crystallography Made Crystal Clear

Crystallography Made Crystal Clear
By Gale Rhodes
Publisher: Academic Press
  • Number Of Pages: 269
  • Publication Date: 2000-01-15
  • ISBN-10 / ASIN: 0125870728
  • ISBN-13 / EAN: 9780125870726
  • Binding: Paperback

Product Description:
Macromolecules are the proteins and nucleic acids upon which life depends. Understanding the action of biological macromolecules (giant molecules) requires detailed knowledge of their structures. Most of the more than ten thousand known structures of protein and nucleic acids were obtained by x-ray crystallography, the standard mechanism for determining protein structure. Essentially, proteins are frozen into rigid crystals, which can be stacked up in a repeating pattern--like supermarket displays. The structure of each individual crystal can be determined by the way x-rays are bent when they pass through the composite crystal. Protein structure is essential when investigating protein interactions and planning drug development.
Crystallography Made Crystal Clear, Second Edition explains how scientists discover the structures of the macromolecules. Scientists do not see these molecules directly. Instead, they build models as a means of interpreting data from x-ray diffraction by crystals, or by irradiation by other forms of energy. Users of these models need to know how they are obtained in order to know what they are seeing when they study a model of a macromolecule. They also need to know how to judge whether conclusions they draw from the molecular models are really supported by the models. This book uses visual and geometric models to help readers understand the mathematics that forms the basis of x-ray crystallography.
The field of protein crystallography is growing every day and has been instrumental in discovering the molecular principles of biology and in discovering new drugs, such as the recent protease inhibitors for AIDS. The field includes the largest percentage of Nobel prizes than any other scientific discipline. Every major university and drug company has a protein crystallography laboratory and this book is an invaluable aid to those wishing to practice protein crystallography or just learn more about how it is actually done.

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Compact Regs Part 11: CFR 21 Part 11 Electronic Records; Electronic Signatures

Compact Regs Part 11: CFR 21 Part 11 Electronic Records; Electronic Signatures .

Compact Regs Part 11: CFR 21 Part 11 Electronic Records; Electronic Signatures (10 Pack)
Publisher: Informa HealthCare Number Of Pages: 24 Publication Date: 2003-10-29 ISBN-10 / ASIN: 0849321867 ISBN-13 / EAN: 9780849321863 Binding: Hardcover Product Description:
The Compact Regs series provides full-text, pocket-sized format (3 3/4 inch x 5 1/2 inch) verbatim reproductions of key US FDA regulations. The texts are complete and have not been altered in any manner from the original sources. They are the perfect low-cost tools for: employees as part of documented GMP training programs, for suppliers/vendors so that they may provide components, labels, and parts with an understanding of FDA requirements, and for each clinical investigator, nurse, and technician to help assure compliance to clinical trial protocols. A keyword index can be found at the end of each booklet.

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Quality (Pharmaceutical Engineering Series)

Quality (Pharmaceutical Engineering Series), Volume 2 (Pharmaceutical Engineering)
By Kate McCormick
  • Publisher: Butterworth-Heinemann
  • Number Of Pages: 275
  • Publication Date: 2002-09-24
  • ISBN-10 / ASIN: 075065113X
  • ISBN-13 / EAN: 9780750651134
  • Binding: Paperback

Product Description:

The Pharmaceutical Engineering Series is a comprehensive reference for the pharmaceutical professional covering all aspects from quality, documentation and validation through manufacturing processes to facility design and management. In 'Quality', Dr Kate McCormick provides the reader with comprehensive coverage of this vital subject, including the quality life cycle, management and cost of quality, GMP, auditing and inspections. This book with the others in the series will become a unique source of reference and educational material for the readership.

Case studies and examples make the book of direct practical relevance to the professional in the pharmaceutical industry
Find the answers you are looking for quickly and easily with clear indexing and referencing
Reference to international standards and practice mean this book will be useful wherever you are working.

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Posted by Kmist at 9:24 PM 0 comments Links to this post

Good Manufacturing Practices and Inspection

Good Manufacturing Practices and Inspection (Quality Assurance of Pharmaceuticals) (Quality Assurance of Pharmaceuticals)
By World Health Organization
  • Publisher: World Health Organization
  • Number Of Pages: 413
  • Publication Date: 2007-06-06
  • ISBN-10 / ASIN: 9241547081
  • ISBN-13 / EAN: 9789241547086
  • Binding: Paperback
Product Description:

Quality assurance of pharmaceutical products is a continuing concern of WHO. Despite efforts made around the world to ensure a supply of quality and effective medicines, substandard, spurious and counterfeit products still compromise health care delivery in many countries. To respond to the global need for adequate quality assurance of pharmaceuticals, WHO's Expert Committee on Specifications for Pharmaceutical Preparations has over the years made numerous recommendations to establish standards and guidelines and to promote the effective functioning of national regulatory and control systems and the implementation of internationally agreed standards by trained personnel. Many of the relevant documents endorsed by the Committee are reproduced in this volume, providing guidance covering all aspects of good manufacturing practices (GMP). Important texts on inspection are also included. Most of the material has been published separately in the Expert Committee's reports. This compendium brings it together to make it more accessible and of greater practical value to those working in faculties of pharmacy, in medicines regulation and control, and in the pharmaceutical industry.

http://rapidshare.com/files/82928562/9789241547086_eng.pdf

http://rapidshare.com/files/83128479/GMP_Inspect_QA_Pharma.zip

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Validation Standard Operating Procedures: A Step by Step Guide for Achieving Compliance in the Pharmaceutical, Medical 2001-12

Validation Standard Operating Procedures: A Step by Step Guide for Achieving Compliance in the Pharmaceutical, Medical
By Syed Imtiaz Haider
  • Publisher: CRC
  • Number Of Pages: 496
  • Publication Date: 2001-12-27
  • ISBN-10 / ASIN: 1574443313
  • ISBN-13 / EAN: 9781574443318
  • Binding: Hardcover
Product Description:

A comprehensive when-and-how-to-do-it guide, this book and CD-ROM combination provides administrative solutions for achieving compliance with key FDA guidelines on good manufacturing practice (GMP), good laboratory practice (GLP), and validation. The text shows readers how to establish test functions and acceptance criteria in compliance with FDA perspectives. The CD-ROM contains 74 template validation standard operating procedures that users can edit and print, customizing the program to their needs. The book and CD work together to minimize the number of forms used and to ensure that the all the correct forms are used, thus avoiding the stress that usually accompanies an FDA audit.

http://rapidshare.com/files/41853767/vsop.zip

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GMP/ISO Quality Audit Manual for Healthcare Manufacturers and Their Suppliers, Sixth Edition

GMP/ISO Quality Audit Manual for Healthcare Manufacturers and Their Suppliers, Sixth Edition, (Volume 2 - Regulations By Leonard Steinborn
  • Publisher: CRC
  • Number Of Pages: 452
  • Publication Date: 2004-04-15
  • ISBN-10 / ASIN: 0849318475
  • ISBN-13 / EAN: 9780849318474
  • Binding: Paperback
Product Description:

Volume 2 of this set contains the full text of the FDA regulations, EC and IPEC guidelines, and ISO/BSI standards referenced in the checklists furnished in Volume I. The book is presented in an convenient, easy-to-read format, organized to provide fast access to the guidelines and regulations of interest.

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Clarke's Analysis of Drugs and Poisons, 3rd Edition, 2004-02

Clarke's Analysis of Drugs and Poisons, Third Edition
By Anthony C. Moffat, M. David Osselton, Brian Widdop, Laurent Y. Galichet
  • Publisher: Pharmaceutical Press
  • Number Of Pages: 2101
  • Publication Date: 2004-02-29
  • ISBN-10 / ASIN: 0853694737
  • ISBN-13 / EAN: 9780853694731
  • Binding: Hardcover
Product Description:

This practical manual and standard reference work provides an authoritative source of analytical data for drugs and poisons. It is intended for use primarily by scientists faced with identifying and quantifying these substances in body fluids, tissue samples and pharmaceutical and industrial products. This completely revised and updated new edition now comprises two volumes housed in a handy slipcase. Clarke's Analysis of Drugs and Poisons is an essential requirement for all forensic and crime laboratories, toxicologists, clinical pharmacology departments, poison information centres, pathologists, clinical toxicologists, hospital pharmacists and analytical chemists. Clarke's Analysis of Drugs and Poisons was previously published as Clarke's Analysis and Identification of Drugs.

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http://rapidshare.com/files/146768333/tclark_ana_drg_pois3ed.zip

Posted by Kmist at 9:02 PM 0 comments Links to this post

Guidelines for Safe Handling of Powders and Bulk Solids

Guidelines for Safe Handling of Powders and Bulk Solids
By Center for Chemical Process Safety (CCPS)
  • Publisher: Wiley-AIChE
  • Number Of Pages: 796
  • Publication Date: 2004-11-15
  • ISBN-10 / ASIN: 0816909512
  • ISBN-13 / EAN: 9780816909513
  • Binding: Hardcover.
Product Description:

Powders and bulk solids, handled widely in the chemical, pharmaceutical, agriculture, smelting, and other industries present unique fire, explosion, and toxicity hazards. Indeed, substances which are practically inert in consolidated form may become quite hazardous when converted to powders and granules. The U.S. Chemical Safety and Hazard Investigation Board is currently investigating dust explosions that occured in 2003 at WestPharma, CTA Acoustics, and Hayes-Lemmerz, and is likely to recommend that companies that handle powders or whose operations produce dust pay more attention to understanding the hazards that may exist at their facility. This new CCPS guidelines book will discuss the types of hazards that can occur in a wide range of process equipment and with a wide range of substances, and will present measures to address these hazards.

Posted by Kmist at 9:00 PM 0 comments Links to this post

Pharmaceutical Guidelines (Every Pharma Industry Must Have)

Common Technical Document:
ASEAN
ICH
GMP -Drug Product:
INDIA
PIC
USFDA
WHO
GMP-Drug substances:
ICH
PIC
USFDA
WHO
ICH Guidelines:
Efficacy
Multidisciplinary
Quality
Safety
Regulatory Audits:
PIC
WHO

http://rapidshare.com/files/67568085/GMP_and_Regulatory_Guidelines.rar

Posted by Kmist at 8:56 PM 0 comments Links to this post

Polymorphism: in the Pharmaceutical Industry

Polymorphism: in the Pharmaceutical Industry
By Rolf Hilfiker
  • Publisher: Wiley-VCH
  • Number Of Pages: 433
  • Publication Date: 2006-04-17
  • ISBN-10 / ASIN: 3527311467
  • ISBN-13 / EAN: 9783527311460
  • Binding: Hardcover
Book Description:

Edited by one of the leading experts in the field, this handbook emphasizes why solid-state issues are important, which approaches should be taken to avoid problems and exploit the opportunities offered by solid state properties in the pharmaceutical and agricultural industries.

With its practical approach, this is at once a guideline for development chemists just entering the field as well as a high-quality source of reference material for specialists in the pharmaceutical and chemical industry, structural chemists, physicochemists, crystallographers, inorganic chemists, and patent departments.

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Polymorphism in Pharmaceutical Solid

Polymorphism in Pharmaceutical Solid (Drugs and the Pharmaceutical Sciences)
By Harry G. Brittain
  • Publisher: Informa HealthCare
  • Number Of Pages: 448
  • Publication Date: 1999-03-03
  • ISBN-10 / ASIN: 0824702379
  • ISBN-13 / EAN: 9780824702373
  • Binding: Hardcover
Product Description:

"Presents a comprehensive examination of polymorphic behavior in pharmaceutical development-demonstrating with clear, practical examples how to navigate complicated crystal structures. Edited by the recipient of the American Association of Pharmaceutical Scientists' 1998 Research Achievement Award in Analysis and Pharmaceutical Quality."

http://rapidshare.com/files/12436523/pphs.rar.html

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Pharmaceutical Pre-Approval Inspections

Pharmaceutical Pre-Approval Inspections: A Guide to Regulatory Success, Second Edition (Drugs and the Pharmaceutical Sciences)
By Martin D. Hynes III
  • Publisher: Informa HealthCare
  • Number Of Pages: 304
  • Publication Date: 2008-03-05
  • ISBN-10 / ASIN: 0849391849
  • ISBN-13 / EAN: 9780849391842
  • Binding: Hardcover
Product Description:

This Second Edition is an essential guide to preparing for FDA pre-approval inspections—taking into account current trends in FDA expectations and inspection activities, such as the GMPs of the 21st Century, quality systems-based approach to inspections, risk-based inspections, quality by design, process analytical technology, design space, etc. The goal of this book is to help organizations gain rapid regulatory approval.

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http://rapidshare.com/files/137661886/tpharma_preappr_inspect2ed.zip



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Pharmaceutical Project Management

Pharmaceutical Project Management, Second Edition (Drugs and the Pharmaceutical Sciences)
By Anthony Kennedy
  • Publisher: Informa HealthCare
  • Number Of Pages: 280
  • Publication Date: 2008-03-17
  • ISBN-10 / ASIN: 0849340241
  • ISBN-13 / EAN: 9780849340246
  • Binding: Hardcover
Product Description:

Encompassing the full spectrum of project management’s role and responsibility encountered in the pharmaceutical industry, Pharmaceutical Project Management outlines the key objectives, risks, and challenges of each stage of the pharmaceutical lifecycle, from discovery and preclinical phases through manufacturing and launch.

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http://rapidshare.com/files/135443232/tpharmap_projmgmt2ed.zip

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Pharmaceutical Process Scale-Up

Pharmaceutical Process Scale-Up (Drugs and the Pharmaceutical Sciences)
By Michael Levin
  • Publisher: Informa Healthcare
  • Number Of Pages: 584
  • Publication Date: 2001-12-12
  • ISBN-10 / ASIN: 0824706250
  • ISBN-13 / EAN: 9780824706258
  • Binding: Hardcover
Product Description:

Focusing on scientific and practical aspects of process scale-up, this resource details the theory and practice of transferring pharmaceutical processes from laboratory scale to the plant and production scale. It covers parenteral and nonparenterel liquids and semi-solids, products derived from biotechnology, dry blending and powder handling, granulation and drying, fluid bed compaction and tableting, and film coating and regulatory requirements for scale-up and postapproval changes. Drawing on the experience of twenty contributing , the book employs dimensional analysis as a unified scientific approach to quantify similar processes on different scales.

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http://rapidshare.com/files/114121199/082474196X.zip

http://rapidshare.com/files/114548480/Pharma_proc_sclup.zip

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Stability of drugs and dosage forms

By Sumie Yoshioka, Valentino J. Stella,
  • Publisher: Springer
  • Number Of Pages: 272
  • Publication Date: 2000-11
  • Sales Rank: 351264
  • ISBN / ASIN: 0306464047
  • EAN: 9780306464041
  • Binding: Hardcover
  • Manufacturer: Springer
  • Studio: Springer
  • Average Rating:
  • Total Reviews:
Book Description:

Drug products are complex mixtures of drugs and excipients and, as such, their chemical and physical stability kinetics are complex. This book discusses the stability of these dosage forms with preformulation studies through to the studies on the final products. The book is intended for graduate students, professionals in the field of Pharmaceutics and Chemistry.

http://rapidshare.com/files/50663431/stability_of_drugs_and_dosage_forms.pdf

http://rapidshare.com/files/50694531/stability_drugs_dosage_forms.zip

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Pharmaceutical Process Validation

Pharmaceutical Process Validation: An International Third Edition (Drugs and the Pharmaceutical Sciences)
By Robert A. Nash, Alfred H. Wachter
  • Publisher: Informa HealthCare
  • Number Of Pages: 776
  • Publication Date: 2003-03-27
  • ISBN-10 / ASIN: 0824708385
  • ISBN-13 / EAN: 9780824708382
  • Binding: Hardcover
Product Description:

The third edition of this text contains additional chapters which cover troubleshooting procedures, validation in contract manufacturing and current harmonization trends.

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New Drug Approval Process

New Drug Approval Process, Fourth Edition, Accelerating Global Registrations (Drugs and the Pharmaceutical Sciences)
By Richard Guarino
  • Publisher: Informa HealthCare
  • Number Of Pages: 664
  • Publication Date: 2004-05-21
  • ISBN-10 / ASIN: 0824750411
  • ISBN-13 / EAN: 9780824750411
  • Binding: Hardcover
Product Description:

Offering expert guidance on the clinical, regulatory, and statistical processes involved in the development of new pharmaceutical product applications for drugs, biologicals, and medical devices, the Fourth Edition details the specific regulations, guidelines, and procedures that will advance and ensure approval of United States and global new product applications. It communicates and integrates a new approach to the world of pharmaceutical personnel on all aspects of new product development and alerts readers to clinical and regulatory tasks that require immediate attention and long-term follow-up in order to comply with the international acceptance of new product approvals.

http://rapidshare.com/files/145241459/ndawqef0824750411.zip


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Bombs, Bugs, Drugs, and Thugs: Intelligence and America's Quest for Security (Fast Track Books)

Bombs, Bugs, Drugs, and Thugs: Intelligence and America's Quest for Security (Fast Track Books)
By Loch Johnson
  • Publisher: NYU Press
  • Number Of Pages: 326
  • Publication Date: 2000-11-01
  • ISBN-10 / ASIN: 0814742521
  • ISBN-13 / EAN: 9780814742525
  • Binding: Hardcover

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The $800 Million Pill: The Truth behind the Cost of New Drugs
By Merrill Goozner.
  • Publisher: University of California Press
  • Number Of Pages: 297
  • Publication Date: 2004-04-22
  • ISBN-10 / ASIN: 0520239458
  • ISBN-13 / EAN: 9780520239456
  • Binding: Hardcover
Product Description:

Why do life-saving prescription drugs cost so much? Drug companies insist that prices reflect the millions they invest in research and development. In this gripping exposé, Merrill Goozner contends that American taxpayers are in fact footing the bill twice: once by supporting government-funded research and again by paying astronomically high prices for prescription drugs. Goozner demonstrates that almost all the important new drugs of the past quarter-century actually originated from research at taxpayer-funded universities and at the National Institutes of Health. He reports that once the innovative work is over, the pharmaceutical industry often steps in to reap the profit.
Goozner shows how drug innovation is driven by dedicated scientists intent on finding cures for diseases, not by pharmaceutical firms whose bottom line often takes precedence over the advance of medicine. A university biochemist who spent twenty years searching for a single blood protein that later became the best-selling biotech drug in the world, a government employee who discovered the causes for dozens of crippling genetic disorders, and the Department of Energy-funded research that made the Human Genome Project possible--these engrossing accounts illustrate how medical breakthroughs actually take place.
The $800 Million Pill suggests ways that the government's role in testing new medicines could be expanded to eliminate the private sector waste driving up the cost of existing drugs. Pharmaceutical firms should be compelled to refocus their human and financial resources on true medical innovation, Goozner insists. This book is essential reading for everyone concerned about the politically charged topics of drug pricing, Medicare coverage, national health care, and the role of pharmaceutical companies in developing countries.

http://rapidshare.com/files/31635930/800MillPill2004.rar

http://rapidshare.com/files/14653505/The._800.Million.Pill.rar

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Clinical Trials of Drugs and Biopharmaceuticals

  • Publisher: CRC
  • Number Of Pages: 520
  • Publication Date: 2005-09-19
  • ISBN-10 / ASIN: 0849321859
  • ISBN-13 / EAN: 9780849321856
  • Binding: Hardcover
Product Description:

The pharmaceutical industry is on the verge of an exciting and challenging century. Advances in pharmaceutical sciences have dramatically changed the processes of discovery and development of new therapeutic drugs and, in turn, resulted in an extraordinary increase in the potential prophylactic and therapeutic interventions. In this atmosphere, an intimate understanding of the mechanisms of pharmacokinetic and pharmacodynamic activity and the processes of drug evaluation is essential.

Clinical Trials of Drugs and Biopharmaceuticals provides an overview of current procedures and major issues involved in drug and biopharmaceutical development. The book examines critical biochemical and pharmaceutical considerations for trials conducted during each phase of clinical development. It also reports information related to early pre-clinical evaluations of pharmacological activities and safety before proceeding with initiation of clinical trials. The sections focus on clinical assessments of drugs and biopharmaceuticals such as cardiovascular, respiratory, central nervous system, gastrointestinal and liver, genitourinary, skin, metabolism, and chemotherapeutic drugs as well as vaccines, biotechnology-derived therapeutics, and plant-based medicines.

Practical and informative, this step-by-step guide includes information on all four phases of clinical trials prior to licensure and covers the design of post-marketing studies. The editors examine how recent advances and increased demand for safer and more effective drugs have changed the process by which drugs are developed and approved.

http://rapidshare.com/files/2325400/Clinical_Trials_of_Drugs_and_Biopharmaceuticals.rar

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Design for Six Sigma : A Roadmap for Product Development

Design for Six Sigma : A Roadmap for Product Development
By Kai Yang, Basem S. EI-Haik
  • Publisher: McGraw-Hill Professional
  • Number Of Pages: 624
  • Publication Date: 2003-05-21
  • ISBN-10 / ASIN: 0071412085
  • ISBN-13 / EAN: 9780071412087
  • Binding: Hardcover
Product Description:

Here's the book that clearly and logically answers the complex question quality managers and product developers face almost every day: WHICH PRODUCT DEVELOPMENT TOOLS SHOULD I USE AND WHEN?

This much-needed, well-written roadmap for robust, efficient product development features:
* All the coverage needed to implement six sigma in any manufacturing concern
* A complete review of both traditional and contemporary design methods
* Systems discussed include: DOE (Design Of Experiment), Taguchi Method, QFD (Quality Function Deployment), Axiomatic Design, and TRIZ (Theory for Inventive Problem-Solving)
* Practical examples to highlight important elements of each system
* A unique multi-systems approach to designing products, incorporating the traditional and contemporary methods discussed, detailing how and when to use them
* Valuable assistance when preparing for certification exams.

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Modern HPLC for Practicing Scientists

Modern HPLC for Practicing Scientists
By Michael W. Dong
  • Publisher: Wiley-Interscience
  • Number Of Pages: 304
  • Publication Date: 2006-06-12
  • ISBN-10 / ASIN: 047172789X
  • ISBN-13 / EAN: 9780471727897
  • Binding: Paperback

Product Description:

A comprehesive yet concise guide to Modern HPLC

Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers.

Topics covered include:

  • HPLC operation
  • Method development
  • Maintenance and troubleshooting
  • Modern trends in HPLC such as quick-turnaround and "greener" methods
  • Regulatory aspects

While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources.

With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

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Method Validation in Pharmaceutical Analysis

Method Validation in Pharmaceutical Analysis: A Guide to Best Practice
By Joachim Ermer, John H. McB. Miller
Publisher: Wiley-VCH
  • Number Of Pages: 418
  • Publication Date: 2005-05-06
  • ISBN-10 / ASIN: 3527312552
  • ISBN-13 / EAN: 9783527312559
  • Binding: Hardcover
Product Description:

Adopting a practical approach, the authors provide a detailed interpretation of the existing regulations (GMP, ICH), while also discussing the appropriate calculations, parameters and tests. The book thus allows readers to validate the analysis of pharmaceutical compounds while complying with both the regulations as well as the industry demands for robustness and cost effectiveness.

Following an introduction to the basic parameters and tests in pharmaceutical validation, including specificity, linearity, range, precision, accuracy, detection and quantitation limits, the text focuses on a life-cycle approach to validation and the integration of validation into the whole analytical quality assurance system. The whole is rounded off with a look at future trends.

With its first-hand knowledge of the industry as well as regulating bodies, this is an invaluable reference for analytical chemists, the pharmaceutical industry, pharmaceutists, QA officers, and public authorities.

Posted by Kmist at 3:03 PM 0 comments Links to this post

Development and Validation of Analytical Methods (Progress in Pharmaceutical and Biomedical Analysis)

  • By C.M. Riley, T.W. Rosanske,
  • Publisher: Pergamon
  • Number Of Pages: 362
  • Publication Date: 1996-05-01
  • Sales Rank: 1066722
  • ISBN / ASIN: 0080427928
  • EAN: 9780080427928
  • Binding: Hardcover
  • Manufacturer: Pergamon
  • Studio: Pergamon
  • Average Rating: 5
  • Total Reviews: 1
Book Description:

The need to validate an analytical or bioanalytical method is encountered by analysts in the pharmaceutical industry on an almost daily basis, because adequately validated methods are a necessity for approvable regulatory filings. What constitutes a validated method, however, is subject to analyst interpretation because there is no universally accepted industry practice for assay validation. This book is intended to serve as a guide to the analyst in terms of the issues and parameters that must be considered in the development and validation of analytical methods. In addition to the critical issues surrounding method validation, this book also deals with other related factors such as method development, data acquisition, automation, cleaning validation and regulatory considerations.

The book is divided into three parts. Part One, comprising two chapters, looks at some of the basic concepts of method validation. Chapter 1 discusses the general concept of validation and its role in the process of transferring methods from laboratory to laboratory. Chapter 2 looks at some of the critical parameters included in a validation program and the various statistical treatments given to these parameters.

Part Two (Chapters 3, 4 and 5) of the book focuses on the regulatory perspective of analytical validation. Chapter 3 discusses in some detail how validation is treated by various regulatory agencies around the world, including the United States, Canada, the European Community, Australia and Japan. This chapter also discusses the International Conference on Harmonization (ICH) treatment of assay validation. Chapters 4 and 5 cover the issues and various perspectives of the recent United States vs. Barr Laboratories Inc. case involving the retesting of samples.

Part Three (Chapters 6 - 12) covers the development and validation of various analytical components of the pharmaceutical product development process. This part of the book contains specific chapters dedicated to bulk drug substances and finished products, dissolution studies, robotics and automated workstations, biotechnology products, biological samples, analytical methods for cleaning procedures and computer systems and computer-aided validation. Each chapter goes into some detail describing the critical development and related validation considerations for each topic.

This book is not intended to be a practical description of the analytical validation process, but more of a guide to the critical parameters and considerations that must be attended to in a pharmaceutical development program. Despite the existence of numerous guidelines including the recent attempts by the ICH to be implemented in 1998, the practical part of assay validation will always remain, to a certain extent, a matter of the personal preference of the analyst or company. Nevertheless, this book brings together the perspectives of several experts having extensive experience in different capacities in the pharmaceutical industry in an attempt to bring some consistency to analytical method development and validation.

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Analytical Method Development and Validation

  • Publisher: CRC
  • Number Of Pages: 96
  • Publication Date: 1997-05-16
  • Sales Rank: 567067
  • ISBN / ASIN: 0824701151
  • EAN: 9780824701154
  • Binding: Paperback
  • Manufacturer: CRC
  • Studio: CRC
  • Average Rating: 3.5
  • Total Reviews: 2
Book Description:

Describes analytical methods development, optimization and validation, and provides examples of successful methods development and validation in high-performance liquid chromatography (HPLC) areas. The text presents an overview of Food and Drug Administration (FDA)/International Conference on Harmonization (ICH) regulatory guidelines, compliance with validation requirements for regulatory agencies, and methods validation criteria stipulated by the US Pharmacopia, FDA and ICH.

http://rapidshare.com/files/42476639/Analytical_Method_Deve_Vali.zip

http://rapidshare.com/files/22510504/amdv.rar


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HPLC Method Development for Pharmaceuticals (Separation Science and Technology, Volume 8)

HPLC Method Development for Pharmaceuticals, Volume 8 (Separation Science and Technology) (Separation Science and Technology)
By Satinder Ahuja, Henrik Rasmussen
  • Publisher: Academic Press
  • Number Of Pages: 532
  • Publication Date: 2007-06-07
  • ISBN-10 / ASIN: 0123705401
  • ISBN-13 / EAN: 9780123705402
  • Binding: Hardcover
Product Description:

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective.
HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.

* Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory
* Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities)
* Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase.

http://rapidshare.com/files/74086251/Ahu9780123705402.rar

http://rapidshare.com/files/74149161/HPLC_Method_Develop_Pharma.zip

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USP NF 2007 (United States Pharmacopeia/National Formulary)



  • Publisher: Not Avail
  • Number Of Pages:
  • Publication Date: 2007-05
  • Sales Rank: 1105649
  • ISBN / ASIN: 1889788473
  • EAN: 9781889788470
  • Binding: Hardcover
  • Manufacturer: Not Avail
  • Studio: Not Avail
  • Average Rating:
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the book was created by lawrence as chm file

The United States Pharmacopeia is a compendium of quality control tests for drugs and excipients to be introduced into a medicinal formulation. It is published every year [1] by the United States Pharmacopoeial Convention. It forms the basis of enforcement actions by the U.S. Food and Drug Administration and the U.S. Drug Enforcement Administration and is the official pharmacopoeia of the U.S.A. and many other nations. Therefore, in case of a dispute, those methods for, amongst others, identification, assay and purity determination of a drug substance or excipient which are stated in the USP will be the legally binding ones.

Within the field the compendium is referred to simply as the USP. The initials USP are affixed to materials' names to indicate that they conform to the specifications in the USP and may be used medicinally.

http://rapidshare.com/files/28302024/USP30-NF25_by_w5a.us.rar

pass: www.w5a.us

http://rapidshare.com/files/40553187/US.Pharmacopeia.2007.USP30-NF25-CHM-1889788473.rar

http://rapidshare.com/files/41539644/USP30-NF25.rar

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Introduction to the Pharmaceutical Regulatory Process (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs)

The Pharmaceutical Regulatory Process (Drugs and the Pharmaceutical Sciences)
By Ira R. Berry
  • Publisher: Informa HealthCare
  • Number Of Pages: 736
  • Publication Date: 2004-11-16
  • ISBN-10 / ASIN: 0824754646
  • ISBN-13 / EAN: 9780824754648
  • Binding: Hardcover
Product Description:

Providing in-depth coverage of the procedures utilized by pharmaceutical companies for regulatory compliance, this reference describes the history and development of regulations, standards, and guidelines that affect pharmaceutical product approval and commercial sale in the United States-standing alone as the only authoritative guide to address the complex web of regulatory requirements, application processes, and quality control issues influencing the pharmaceutical industry.

http://rapidshare.com/files/18808661/TPRP.rar.html

http://rapidshare.com/files/43938499/Pharma_Regu_Proce.rar

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FDA Regulatory Affairs: A Guide for Prescription Drugs, Medical Devices, and Biologics

FDA Regulatory Affairs: A Guide for Prescription Drugs, Medical Devices, and Biologics
By Douglas J. Pisano, David Mantus
  • Publisher: Informa HealthCare
  • Number Of Pages: 360
  • Publication Date: 2003-12-23
  • ISBN-10 / ASIN: 1587160072
  • ISBN-13 / EAN: 9781587160073
  • Binding: Paperback
Product Description:

Since the enactment of the first drug law in 1848, the legislation surrounding drug development has evolved into a maze of regulations that can be hard to navigate. Not only are existing regulations constantly reviewed and updated, the increasingly rapid rate of development in the pharmaceuticals field creates new issues that need to be addressed by new legislation. Written in plain language without confusing jargon or legalese, FDA Regulatory Affairs: A Guide for Prescription Drugs, Medical Devices, and Biologics provides a roadmap to the myriad and sometimes confusing regulations that govern this constantly changing field. The book examines the pertinent aspects of the Federal Food, Drug, and Cosmetic Act as they apply to human drug and device development, research, manufacturing, and marketing. It focuses on the new drug approval process, cGMPs, GCPs, quality system compliance, and the corresponding documentation requirements. Although there are a number of references on these topics, this book is unique in that it is written in a general, easy to read prose style. It presents information drawn from a wide range of resources in a single, easy to use format. FDA approval can be a lengthy and expensive process. In order for a pharmaceutical manufacturer to place a product on the market for human use, a multiphase procedure must be followed. Providing a reference for students, professionals, and especially those who are charged with the day-to-day tasks of assuring regulatory compliance under FDA guidelines, this book demystifies the inner workings of the FDA and allows you to understand how it operates with respect to product approval.

http://rapidshare.com/files/2177823/FDA_Regulatory_Affairs.rar



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Patent, Copyright & Trademark: An Intellectual Property Desk Reference

Patent, Copyright & Trademark: An Intellectual Property Desk Reference
(Patent, Copyright and Trademark)
By Stephen Elias, Richard Stim
  • Publisher: Nolo Press
  • Number Of Pages: 518
  • Publication Date: 2003-05
  • ISBN-10 / ASIN: 0873379497
  • ISBN-13 / EAN: 9780873379496
  • Binding: Paperback
Book Description:

Whether you're an Edison, Faulkner or Gates, you need Patent, Copyright & Trademark.

Intellectual property law has rapidly produced its own language. But don't count on understanding it right off the bat -- the language baffles lawyers and lay folk alike. Whether you're an inventor, designer, writer or programmer, you need to understand the language of intellectual property law to intelligently deal with such issues as:

*who owns creative works or valuable information
*how these owners can protect and enforce their ownership rights
*how disputes between intellectual-property owners can be resolved
*how ownership rights can best be transferred to others
*and many more

With this essential guide, you will:

*get clear and concise overviews of patent copyright, trademark and trade secret law
*understand the different kinds of protection offered by patents, copyrights, trademarks and trade secrets -- and which apply to your work
*get a plain-English definition of every term you're likely to come across
*find the information you need, quickly and easily -- all entries are organized by topic and extensively cross-referenced

Exhaustively updated, the 6th edition provides all-new information regarding the protection of idea submissions and fictional characters, new uses for end-user agreements, the failure of UCITA, the Supreme Court's ruling in the "Victoria's Secret" case -- and much, much more.

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Inside the Minds: The Art & Science of Patent Law 2003-12

  • Publisher: Aspatore Books
  • Number Of Pages: 250
  • Publication Date: 2003-12
  • Sales Rank: 1716564
  • ISBN / ASIN: 1587623463
  • EAN: 9781587623462
  • Binding: Paperback
  • Manufacturer: Aspatore Books
  • Studio: Aspatore Books
  • Average Rating: 0
  • Total Reviews: 0

Book Description:

Inside the Minds: The Art & Science of Patent Law is an authoritative, insider's perspective on the laws which govern patents, the characteristics and capabilities of the successful practitioner and the future of patent regulation, on a global scale. Featuring Department Heads, Group Chairs and Leading Partners, all representing some of the nation's top firms, this book provides a broad, yet comprehensive overview of the practice of patent law, discussing the current shape and future state of patent regulation, from the founding doctrines, to the pivotal cases of today. From the steps involved in evaluating an developing filing strategies, to tactics around profiting from a patent portfolio and preventing infringement, these authors articulate the finer points around patents now, and what will hold true into the future. The different niches represented and the breadth of perspectives presented enable readers to get inside some of the great legal minds of today as experts offer up their thoughts around the keys to success within this fascinating practice area - where law, technology and strategy intersect.

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Essentials of Intellectual Property (Essentials Series)

Essentials of Intellectual Property (Essentials Series)
By Alexander I. Poltorak, Paul J. Lerner
  • Publisher: Wiley
  • Number Of Pages: 288
  • Publication Date: 2002-04-01
  • ISBN-10 / ASIN: 0471209422
  • ISBN-13 / EAN: 9780471209423
  • Binding: Paperback

Product Description:

ESSENTIALS OF INTELLECTUAL PROPERTY

Full of valuable tips, techniques, illustrative real-world examples, exhibits, and best practices, this handy and concise paperback will help you stay up to date on the newest thinking, strategies, developments, and technologies in intellectual property.

"Alexander Poltorak and Paul Lerner have written the definitive primer on intellectual property for business professionals. Thorough in its coverage and understandable in its delivery, Essentials of Intellectual Property provides not only an outstanding summary of intellectual property basics, but a useful and sensible strategy for using intellectual property to the best needs of a business. Poltorak and Lerner have combined their in-depth knowledge of patent law with their savvy business skills to yield an indispensable reference for the business professional."
—Jeffrey L. Brandt, Patent Attorney, Former Senior Vice President and Intellectual Property & Licensing Counsel, priceline.com

"Alex Poltorak and Paul Lerner have pulled off a mighty feat with Essentials of Intellectual Property. They have crafted a work that is clear for the beginning practitioner while nuanced and sophisticated for the savvy tech transfer and IP management veteran. Lively and often witty writing is a treat not often found in tomes on what can be a dry subject. With Essentials of Intellectual Property, the practitioner has a new literary tool for tying IP strategy to the business reality of tomorrow."
—Edward Kahn, Founder and President, EKMS, Inc., Cambridge, MA

"This critically important new volume of work not only provides the professional with a greater knowledge of this vast subject, but also the novice with a better understanding and appreciation for the results of their creative abilities."
—Lawrence J. Udell, Executive Director, California Invention Center, Professor of New Ventures and Entrepreneurship

The Wiley Essentials Series—because the business world is always changing...and so should you.

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The Fire of Invention, The Fuel of Interest: On Intellectual Property (Pfizer Lecture Series)

The Fire of Invention, The Fuel of Interest: On Intellectual Property (Pfizer Lecture Series)
By Michael Novak
Publisher: AEI Press
  • Number Of Pages: 51
  • Publication Date: 1996-12-25
  • ISBN-10 / ASIN: 0844770817
  • ISBN-13 / EAN: 9780844770819
  • Binding: Paperback
Product Description:

This book discusses the moral and practical foundations of the corporation and corporate governance.

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Competition Law and Patents: A Follow-on Innovation Perspective in the Biopharmaceutical Industry

Competition Law and Patents: A Follow-on Innovation Perspective in the Biopharmaceutical Industry
(New Horizons in Competition Law and Economics)
By Irina Haracoglou
  • Publisher: Edward Elgar Publishing
  • Number Of Pages: 251
  • Publication Date: 2008-03-31
  • ISBN-10 / ASIN: 1847205992
  • ISBN-13 / EAN: 9781847205995
  • Binding: Hardcover.

http://rapidshare.com/files/131051946/1847205992.rar

http://rapidshare.com/files/131260102/Compet_law_paten.zip

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Patent Fundamentals for Scientists and Engineers, Second Edition

Patent Fundamentals for Scientists and Engineers, Second Edition
By Thomas T. Gordon, Arthur S. Cookfair
  • Publisher: CRC
  • Number Of Pages: 176
  • Publication Date: 2000-03-15
  • ISBN-10 / ASIN: 1566705177
  • ISBN-13 / EAN: 9781566705172
  • Binding: Paperback
Book Description:

International in scope, Patent Fundamentals for Scientists and Engineers, Second Edition provides a clear explanation of the patent system and patent principles. Designed for non-lawyers, this book includes information on the patenting process, obtaining patent protection, and how to recognize patentable inventions and avoid legal problems of infringement. New in the Second Edition: · Techniques for searching the Internet · Internet addresses for patent information and references · A new chapter providing the forms required to file a patent · Expanded coverage of international patents The nontechnical style of this book makes it easy to read and understand. By providing a basic working knowledge of patents, Patent Fundamentals for Scientists and Engineers, Second Edition enables non-specialists to make well-informed decisions affecting new and patentable products. It is an ideal book for anyone without prior legal knowledge who needs to understand the patent system, including scientists, engineers, inventors, researchers, business managers, entrepreneurs, and patent liaison workers.

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Significant Pharmaceuticals Reported in US Patents

Significant Pharmaceuticals Reported in US Patents
By Thomas F. DeRosa
Publisher: Elsevier Science
  • Number Of Pages: 700
  • Publication Date: 2007-06-11
  • ISBN-10 / ASIN: 0080453449
  • ISBN-13 / EAN: 9780080453446
  • Binding: Hardcover
Product Description:

This book identifies the next generation of pharmaceuticals reported in US Patents. This "hands-on" title provides explicit laboratory methods for preparing the most recent and effective medications. Each entry documents the biological testing protocols used to evaluate a drug and the significance of the current treatment agent over previous methods. Pharmaceuticals are included in this review only if at least two of the following criteria were met: Effectiveness in treating an illness, Innovative, ease of preparation, synergy with existing Medications.
Pharmaceuticals are reported for 27 separate classes of illness, including;
AIDS, Alzheimer's Disease, Cardiovascular Disorders, Diabetes, Epilepsy, Hepatitis C, Osteoporosis, Obesity and Sleep Disorders.
Significant Pharmaceuticals Reported in US Patents has been designed to be used as both a reference and synthetic guide for pharmaceutical, medicinal and organic chemists and graduate students.
Researchers working in other areas will also find the information valuable as in many instances intermediates or the next generation pharmaceutical are readily convertible into other industrial products including: anti-oxidants, chemical additives, herbicides, polymer precursors, water purification agents. Clear structural depictions of reagents and chemical transformations have been supplied to permit the identification of other future applications.

* Identifies next generation pharmaceuticals
* Provides practical preparation methods for each active agent and derivatives
* Documents the analytical characterization and biological testing results of active agents.

http://rapidshare.com/files/45881035/Significant_Pharma_Rep.zip

http://rapidshare.com/files/43557783/Significant-Pharmaceuticals-Reported-in-US-Patents-0080453449.rar

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Nolo's Patents for Beginners, 4th Edition 2004-08

Nolo's Patents for Beginners
By: David Pressman Richard Stim
ISBN: 1413300715
Publisher: NOLO - 2004-08
Paperback | 4th Edition | 240 Pages | List Price: $29.99 (USD) | Sales Rank: 573994
Product Dimensions: 8.98 x 7.14 x 0.48 inches

Do you toil away in an office, garage or basement lab in the hopes of bringing a new widget to life? What will you do when it's alive and kicking?

Here's the primer every first-time inventor needs. Packed with plain-English explanations and step-by-step instructions, Nolo's Patent for Beginners defines clearly and simply what a patent is and why you need one. The book shows you:

*how to document an for maximum protection
*how to tackle the time-and-money-saving, patent-searching process
*the patent process
*who owns a patent
*how to avoid patent infringement

The 4th edition is completely updated and revised to reflect current law and court rulings, including the Supreme Court's decision in the controversial "Festo" case.
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Patents in the Knowledge-Based Economy

Patents in the Knowledge-Based Economy
By
Committee on Intellectual Properity Rights in the Knowledge-Based Economy, National Research Council
  • Publisher: National Academies Press
  • Number Of Pages: 352
  • Publication Date: 2004-08-20
  • ISBN-10 / ASIN: 0309086361
  • ISBN-13 / EAN: 9780309086363
  • Binding: Paperback.

http://rapidshare.com/files/3751750/10770.rar

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Information Sources in Patents

Information Sources in Patents (Guides to Information Sources) (Guides to Information Sources)
By Stephen R. Adams
Publisher: K. G. Saur
  • Number Of Pages: 236
  • Publication Date: 2005-08-15
  • ISBN-10 / ASIN: 3598244436
  • ISBN-13 / EAN: 9783598244438
  • Binding: Hardcover
Product Description:

The completely new edition of this well respected reference work is aimed at information specialists and librarians as well as anyone needing to know where and how can be found. The author discusses patent information within the context of the current legal framework for patents both from a national and international perspective. It also includes a chapter on future developments and their likely effect on patent information. In order to make successful use of patent information sources, it is essential that the reader fully understands the three major patent . The author therefore provides detailed descriptions of The European Patent System, The Unites States Patent System and The Japanese Patent System. He carefully explains the way patents are documented within these regions and the idiosyncrasies and similarities between the systems. Having explained the different patent regions, the author moves on to provide details of information sources on different media paper, disk, online and the . He includes alerting searches, patentability, portfolio and legal status searches and commercial intelligence which includes a discussion on patent analysis . Patent information needs within different subject fields varies and the author has included detailed information on the specialist techniques required in the engineering, and life sciences sectors. In addition there is a glossary of patenting terms, a contact list for major databases and an index of abbreviations. This is an essential reference tool for academic libraries and for anyone requiring information about patents.

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Saturday, September 20, 2008

Static Headspace-Gas Chromatography: Theory and Practice

Description: The only reference to provide both current and thorough coverage of this important analytical technique Static headspace-gas chromatography (HS-GC) is an indispensable technique for analyzing volatile organic compounds, enabling the analyst to assay a variety of sample matrices while avoiding the costly and time-consuming preparation involved with traditional GC. Static Headspace-Gas Chromatography: Theory and Practice has long been the only reference to provide in-depth coverage of this method of analysis. The Second Edition has been thoroughly updated to reflect the most recent developments and practices, and also includes coverage of solid-phase microextraction (SPME) and the purge-and-trap technique. Chapters cover: * Principles of static and dynamic headspace analysis, including the evolution of HS-GC methods and regulatory methods using static HS-GC * Basic theory of headspace analysis-physicochemical relationships, sensitivity, and the principles of multiple headspace extraction * HS-GC techniques-vials, cleaning, caps, sample volume, enrichment, and cryogenic techniques * Sample handling * Cryogenic HS-GC * Method development in HS-GC * Nonequilibrium static headspace analysis * Determination of physicochemical functions such as vapor pressures, activity coefficients, and more Comprehensive and focused, Static Headspace-Gas Chromatography, Second Edition provides an excellent resource to help the reader achieve optimal chromatographic results. Practical examples with original data help readers to master determinations in a wide variety of areas, such as forensic, environmental, pharmaceutical, and industrial applications.

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Modern Practice of Gas Chromatography

Modern Practice of Gas Chromatography
By Robert L., PhD Grob, Eugene F., PhD Barry
Publisher: Wiley-Interscience
  • Number Of Pages: 1064
  • Publication Date: 2004-06-11
  • ISBN-10 / ASIN: 0471229830
  • ISBN-13 / EAN: 9780471229834
  • Binding: Hardcover
Book Description:

The gas chromatography-offering everything the professional and the novice need to know about running, maintaining, and interpreting the results from GC
Analytical chemists, technicians, and scientists in allied disciplines have come to regard Modern Practice of Gas Chomatography as the standard reference in gas chromatography. In addition to serving as an invaluable reference for the experienced practitioner, this bestselling work provides the beginner with a solid understanding of gas chromatographic theory and basic techniques.
This new Fourth Edition incorporates the most recent developments in the field, including entirely new chapters on gas chromatography/mass spectrometry (GC/MS); optimization of separations and assistance; high speed or fast gas chromatography; mobile phase requirements: gas system requirements and sample preparation techniques; qualitative and quantitative analysis by GC; updated information on detectors; validation and QA/QC of chromatographic methods; and useful hints for good gas chromatography.
As in previous editions, contributing authors have been chosen for their expertise and active participation in their respective areas. Modern Practice of Gas Chromatography, Fourth Edition presents a well-rounded and comprehensive overview of the current state of this important technology, providing a practical reference that will greatly appeal to both experienced chomatographers and novices.

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HPLC: A Practical Guide

HPLC: A Practical Guide (Chromatography Monographs)
By T. Hanai
Publisher: Royal Society of Chemistry
  • Number Of Pages: 150
  • Publication Date: 2004-10-20
  • ISBN-10 / ASIN: 0854045155
  • ISBN-13 / EAN: 9780854045150
  • Binding: Hardcover.

http://rapidshare.com/files/75224871/HPLC..A..Practical..Guide.rar

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Basic Gas Chromatography

By Harold M. McNair, James M. Miller,
  • Publisher: Wiley-Interscience
  • Number Of Pages: 200
  • Publication Date: 1998-01-15
  • Sales Rank: 379241
  • ISBN / ASIN: 0471172618
  • EAN: 9780471172611
  • Binding: Paperback
  • Wiley-Interscience
  • Studio: Wiley-Interscience
  • Average Rating: 4
  • Total Reviews: 6
Description:

Gas Chromatography (GC) is undoubtedly the most widely used technique for the separation and analysis of volatile compounds. Yet comprehensive guides to contemporary GC theory and practice are surprisingly hard to find.
Basic Gas Chromatography fills this significant void in the GC literature. Written by two well-known practitioners and educators in GC, it offers thorough coverage of the basic principles and techniques of modern gas chromatography.
Designed to serve as a primer/working reference for bench chemists and as a textbook for upper-level undergraduate and graduate students, it presents the fundamentals in a straightforward and logical. Theoretical issues are explained without complicated equations and derivations and always in terms of how they relate to practical operating principles. Timely, comprehensive, and accessible, Basic Gas Chromatography:
* Provides a balanced of theory and practice
* Includes both capillary column and packed column chromatography
* Uses the new IUPAC terms throughout, cross-referenced to traditional terms and symbols
* Offers a wealth of helpful hints, step-by-step guidelines, and trouble-shooting tips
* Briefly covers GC-MS, headspace analysis, chiral analysis, solid phase microextraction, and other cutting-edge topics.

http://rapidshare.com/files/5031696/Basic_Gas_Chromatography__H._M._McNair___J._M._Miller_.pdf



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Handbook of Pharmaceutical Analysis

Down Load Link:http://rapidshare.com/files/41849348/hopa.rar

Handbook of Pharmaceutical Analysis

edited by Lena Ohannesian and Anthony J. Streeter

Language: English
ISBN: 0824704622
Format: pdf
Size: 5,6 Mb
Pages: 585 pages


With nearly 2,000 references and more than 300 tables, equations, drawings, and the Handbook of Pharmaceutical Analysis is an invaluable source for analytical, bioanalytical, pharmaceutical, organic, clinical, medicinal, physical, quality control, and process chemists and biochemists; pharmaceutical scientists; and upper-level undergraduate and graduate students in these disciplines.
Contents
Form Selection of Pharmaceutical Compounds
Preparation of Drug Samples for Analysis
High-Performance Liquid Chromatography
Mass Spectrometry in Pharmaceutical Analysis
Ultraviolet�Visible Spectroscopy
Immunoassay Techniques
of Capillary Electrophoresis Technology in the Pharmaceutical Industry
Atomic Spectroscopy
Luminescence Spectroscopy
Solid-State Nuclear Magnetic Resonance Spectroscopy
Vibrational Spectroscopy
Statistical Considerations in Pharmaceutical Process Development and



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Thursday, September 18, 2008

Handbook of Pharmaceutical Excipients

By Raymond C. Rowe,&nbspPaul J. Sheskey,&nbspSiân C. Owen,
  • APhA Publications
  • Number Of Pages: 850
  • Publication Date: 2005-12-14
  • Sales Rank: 214481
  • ISBN / ASIN: 1582120587
  • EAN: 9781582120584
  • Binding: Hardcover
  • Manufacturer: APhA Publications
  • Studio: APhA Publications
  • Average Rating: 5
  • Total Reviews: 2

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The Aqueous Cleaning Handbook: A Guide to Critical-Cleaning Procedures, Techniques and Validation, 3rd Edition

The Aqueous Cleaning Handbook: A Guide to Critical-Cleaning Procedures, Techniques and Validation

By Malcolm C McLaughlin, Alan S Zisman

Publisher: The Morris-Lee Publishing Group
  • Number Of Pages:
  • Publication Date: 2002-12
  • ISBN-10 / ASIN: 0972347801
  • ISBN-13 / EAN: 9780972347808
  • Binding: Hardcover
Book Description:

This book distills and presents practical information covering the history of aqueous cleaners-- what they are, how they work, and how to make best use of them in and components in electronics, metalworking, precision manufacturing, food-and-beverage, pharmaceutical, and processing; and many other industrial applications.

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Guidelines for Process Hazards Analysis (PHA, HAZOP), Hazards Identification, and Risk Analysis

Guidelines for Process Hazards Analysis (PHA, HAZOP), Hazards Identification, Risk Analysis
By Nigel Hyatt
  • Publisher: CRC
  • Number Of Pages: 474
  • Publication Date: 2003-03-03
  • ISBN-10 / ASIN: 0849319099
  • ISBN-13 / EAN: 9780849319099
  • Binding: Paperbac
Description:

This unique manual is a comprehensive, easy-to-read overview of hazards analysis as it applies to the process and allied . The book begins by building a background in the technical definition of risk, past industrial incidents and their impacts, ensuing legislation, and the and terms of the risk field. It addresses the different types of structured analytical techniques for conducting Process Hazards Analyses (PHA), provides a "What If" checklist, and shows how to organize and set up PHA sessions. Other topics include layout and siting considerations, Failure Modes and Effect Analysis (FMEA), human factors, loss of containment, and PHA team leadership issues.

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Catalysts for Fine Chemical Synthesis, Regio- and Stereo-Controlled Oxidations and Reductions (Catalysts For Fine Chemicals Synthesis)

Catalysts for Fine Chemical Synthesis, Regio- and Stereo-Controlled Oxidations and Reductions (Catalysts For Fine Chemicals Synthesis)
By Stanley M. Roberts, John Whittall
  • Publisher: Wiley-Interscience
  • Number Of Pages: 336
  • Publication : 2007-09-24
  • ISBN-10 / ASIN: 0470090227
  • ISBN-13 / EAN: 9780470090220
  • Binding: Hardcover
Product Description:

Volume 5 in the Catalysts for Fine Chemical Synthesis series describes new procedures for the regio- and stereo-controlled transformations of compounds involving oxidation or reduction reactions. It describes a wide range of catalysts, including organometallic , biocatalysts and biomimetics. This volume also includes descriptions of a variety of conversions, including: Baeyer-Villiger oxidations; Epoxidation reactions; Hydroxylation reactions; Oxidation of alcohols to aldehydes, ketones and carboxylic acids; Reduction of ketones; and Reduction of alkenes including α, β-unsaturated carbonyl compounds. The \ will be an important text for practising synthetic organic chemists in industry and academia.

  • Protocols are written in a standard format by the authors who have discovered them
  • Hints, tips and safety advice (where appropriate) is given to ensure that the procedures are reproducible
  • Indications are given as to the range of starting materials used and, where appropriate, comparisons to alternative methodology
  • Includes relevant references to the literature.

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Generic Drug Formulations

A selection of about 500 formulations of human and veterinary drugs are presented in this booklet. They have all been developed in the last 20 years in the Laboratories of BASF AG and are in solid, liquid, and semi-solid form. However, emphasis is placed on tablets. Human and veterinary medicines have not been dealt with in separate chapters, because the technologies and excipients are the same.

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Crystallography

By Dieter Schwarzenbach
  • Publisher: Wiley
  • Number Of Pages: 252
  • Publication Date: 1997-04-21
  • Sales Rank: 3169439
  • ISBN / ASIN: 0471955981
  • EAN: 9780471955986
  • Binding: Hardcover
  • Manufacturer: Wiley
  • Studio: Wiley
  • Average Rating:

Book Description:

Due to its interdisciplinary nature, crystallography is of major importance to a wide range of scientific disciplines including physics, chemistry, molecular biology, materials science and mineralogy. However, information is currently divided amongst traditional physics, chemistry and materials science books. This book collates previously disparate literature into one comprehensive and practical source, providing a thorough understanding of the information contained in crystallographic data files and the of x-ray diffraction methods. The book has been written for final year and students.

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Methods of Analysis of Food Components and Additives (Chemical and Functional Properties of Food Components Series)

Methods of Analysis of Food Components and Additives (Chemical and Functional Properties of Food Components Series)
By Semih Otles


  • Publisher: CRC
  • Number Of Pages: 456
  • Publication Date: 2005-04-26
  • ISBN-10 / ASIN: 0849316472
  • ISBN-13 / EAN: 9780849316470
  • Binding: Hardcover


Book Description:

With diet and health news making headlines on a regular basis, the ability to separate, identify, and analyze the nutrients, additives, and toxicological compounds found in food and food compounds is more important than ever. This requires proper training in the application of the best methods, as well as knowledgeable efforts to improve existing methods to meet certain analytical needs. Methods of Analysis for Food Components and Additives is a concise guide to both new and established methods for the analysis of food components and additives. The book presents detailed explanations of modern methods of analysis by 32 leading scientists, many of whom personally developed or refined the techniques. They summarize key findings on novel methods of analysis of food components, additives, and contaminants, including the identification, speciation, and determination of components in raw materials and food products. Each chapter is structured to provide a description of the component or additive that can be analyzed, a simple method explanation of how it works, examples of and references for more specific information. This comprehensive volume features all major classes of food components and contaminants, along with components of current interest to the nutraceutical and functional foods . It is an essential reference for food scientists and chemists, as well as food manufacturers and researchers interested in the many methods of food analysis.

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Approaches to Design and Synthesis of Antiparasitic Drugs (Pharmacochemistry Library)

Approaches to Design and Synthesis of Antiparasitic Drugs (Pharmacochemistry Library)
By N. Anand, S. Sharma†
Elsevier Science
  • Number Of Pages: 524
  • Publication Date: 1997-10-01
  • ISBN-10 / ASIN: 0444894764
  • ISBN-13 / EAN: 9780444894762
  • Binding: Hardcover.

http://rapidshare.com/files/67238680/04448sh_arma94764.rar

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Analysis of Pesticides in Food and Environmental Samples

Analysis of pesticides in Food and Environmental Samples
By Jose L. Tadeo
Publisher: CRC
  • Number Of Pages: 384
  • Publication Date: 2008-02-07
  • ISBN-10 / ASIN: 0849375525
  • ISBN-13 / EAN: 9780849375521
  • Binding: Hardcover
Product Description:

Developing safety regulations for pesticides used around the world—in excess of 2.5 million tons annually—requires reliable analytical methods for assessing their impact in food and in the environment. Analysis of Pesticides in Food and Environmental Samples presents the most effective techniques for analyzing pesticide residues and other contaminants in foods as well as in soil, and air.

Renowned Scientists Report New Data and Advances in the Field

The book introduces sample preparation, extraction, and analytical methods specific to each sample type, including foods from vegetal and animal origin. Other chapters discuss important aspects of and the applicability of hyphenated analytical techniques. In addition to a practical chapter on the use of biosensors and immunoassays for monitoring and gathering exposure data, the book addresses regulatory aspects and presents current data on the levels of pesticides found in food and environmental matrices.

Latest Methods Help Scientists Develop Safer, More Effective Pesticides

Analysis of Pesticides in Food and Environmental Samples enables scientists to measure and predict the behavior and toxicity of pesticides with a higher of accuracy. The methodologies and insight in this timely work will contribute to the development of more effective, less toxic pesticides as well as better safety regulations.

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Prudent Practices in the Laboratory

By National Research Council
  • Publisher: Other
  • Number Of Pages: 427
  • Publication Date: 1998-05-26
  • Sales Rank: 84730
  • ISBN / ASIN: 0309052297
  • EAN: 9780309052290
  • Binding: Hardcover
  • Manufacturer: Other
  • Studio: Other
  • Average Rating: 5
Combines and updates two informative and useful books.

Prudent Practices has combined and updated two of the most useful and informative books on available. This is a must for chemical technicians, researchers and hazardous waste managers! The book(s) gives concise information on general chemical lab safety, proposes procedures for monitoring experiments, controlling waste and uncovering hazardous situations.

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Thermodynamics Problem Solver ( Problem Solvers )

Thermodynamics Problem Solver (Problem Solvers)
By The Staff of REA, Ralph Pike
Publisher: Research &
  • Number Of Pages: 1104
  • Publication Date: 1984-12-14
  • ISBN-10 / ASIN: 0878915559
  • ISBN-13 / EAN: 9780878915552
  • Binding: Paperback.
http://rapidshare.com/files/92289202/thprsor.rar
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MOLECULE THAT CHANGED THE WORLD

Publisher: Wiley-VCH
  • Number Of Pages: 385
  • Publication Date: 2008-03-20
  • ISBN-10 / ASIN: 3527309837
  • ISBN-13 / EAN: 9783527309832
  • Binding: Hardcover

In this delightfully designed book, K. C. Nicolaou introduces the world's most important molecules and shows in a fascinating way the role certain compounds have to play in our everyday lives in the fields of drugs, aromatics or . For example, he tells the story of Aspirin, beginning 3,500 years ago in through to its first synthesis and various many entertaining facts and details. Printed in full color throughout and with its oversize format, this is a must for every chemist, natural scientist and anyone interested in the sciences.

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Wednesday, September 17, 2008

Handbook of Chemoinformatics: From Data to Knowledge (Representation of Molecular Structures

Publisher: Wiley-VCH
  • Number Of Pages: 1930
  • Publication Date: 2003-10-24
  • ISBN-10 / ASIN: 3527306803
  • ISBN-13 / EAN: 9783527306800
  • Binding: Hardcover
Product Description:

Covering the application of computer-aided methods to problems, such as structural databases, spectra interpretation, predicting chemical properties and molecular shapes, this four-volume work provides both newcomers and advanced users as well as lecturers with a profound and comprehensive overview of this increasingly important field.

Closely related to practice, this handbook leads readers step-by-step through:

  • Representation of molecular structures
  • Data types
  • Databases/Datasources
  • Search methods
  • Methods for data analysis
  • Applications

In addition, teach future users how to use different chemoinformatic , while many aspects are treated in special supplementary chapters, such that even specialists learn of the latest developments and trends.

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Academic Press
  • Number Of Pages: 268
  • Publication Date: 2002-08-27
  • ISBN-10 / ASIN: 012451071X
  • ISBN-13 / EAN: 9780124510715
  • Binding: Hardcover

Description:

Electromagnetism, quantum mechanics, statistical mechanics, molecular spectroscopy, optics and radiation form the foundations of the field. On top of these rest the techniques applying the fundamentals (e.g. Emission Spectroscopy, Laser Induced Fluorescence, Raman Spectroscopy). This book contains the basic topics associated with optical spectroscopic techniques. About 40 major sources are distilled into one book, so researchers can read and fully comprehend specific optical spectroscopy techniques without visiting many sources.

Optical diagnostics are widely used in combustion . Ideas first proposed here are now applied in other fields, including reacting flows for materials production (CVD reactors, oxidation reactors and some plasma work), atmospheric sensing, measuring constituents of exhaled human breath (to indicate stress in and the lungs and hence,e.g., provide a very early indicator of lung cancer).

Researchers not formally trained who apply spectroscopy in their research need the detail in this book to ensure accuracy of their technique or to develop more sophisticated measurements.
Time is valuable and future research will benefit. Learning "on the fly" can involve direct information on a specific diagnostic technique rather than gaining the background necessary to go into further depth.

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Handbook of Culture Media for Food Microbiology, 2nd edition (Progress in Industrial Microbiology)

Product Description:

This is a completely revised edition, including new material, from 'Culture Media for Food Microbiology' by J.E.L. Corry et al., published in Progress in Industrial Microbiology, Volume 34, Second Impression 1999.

Written by the Working Party on Culture Media, of the International Committee on Food Microbiology and Hygiene, this is a handy reference for microbiologists wanting to know which media to use for the detection of various groups of microbes in food, and how to check their performance.

The first part comprises reviews, written by international experts, of the media designed to isolate the major groups of microbes important in food spoilage, food fermentations or food-borne disease. The history and rationale of the selective agents, and the indicator systems are considered, as well as the relative merits of the various media. The second part contai

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ns monographs on approximately 90 of the most useful media.

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Handbook of Soil Analysis: Mineralogical, Organic and Inorganic Methods

Table of Contents Part. 1 Mineralogical analysis Ch. 1 Water content and loss on ignition 3 Ch. 2 Particle size analysis 15 Ch. 3 Fractionation of the colloidal systems 65 Ch. 4 Mineralogical characterisations by x-ray diffractometry 83 Ch. 5 Mineralogical analysis by infra-red spectrometry 133 Ch. 6 Mineralogical separation by selective dissolution 167 Ch. 7 Thermal analysis 221 Ch. 8 Microscopic analysis 253 Part. 2 Organic analysis Ch. 9 Physical fractionation of organic matter 289 Ch. 10 Organic and total C, N. (H, O, S) analysis 327 Ch. 11 Quantification of humic compounds 371 Ch. 12 Characterization of humic compounds 399 Ch. 13 Measurement of non-humic molecules 453 Ch. 14 Organic forms of nitrogen, mineralizable nitrogen (and carbon) 497 Part. 3 Inorganic analysis : exchangeable and total elements Ch. 15 pH measurement 551 Ch. 16 Redox potential 581 Ch. 17 Carbonates 593 Ch. 18 Soluble salts 605 Ch. 19 Exchange complex 629 Ch. 20 Isoelectric and zero charge points 645 Ch. 21 Permanent and variable charges 657 Ch. 22 Exchangeable cations 667 Ch. 23 Exchangeable acidity 677 Ch. 24 Lime requirement 687 Ch. 25 Exchange selectivity, cation exchange isotherm 697 Ch. 26 Cation exchange capacity 709 Ch. 27 Anion exchange capacity.

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Statistics And Chemometrics for Analytical Chemistry
Publisher: Pearson Prentice Hall
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Modern Methods of Organic Synthesis

Publisher:
Cambridge University Press
  • Number Of Pages: 506
  • Publication Date: 2004-11-08
  • ISBN-10 / ASIN: 0521770971
  • ISBN-13 / EAN: 9780521770972
  • Binding: Hardcover.
  • Product Description:

    Covering modern methods in organic synthesis, the fourth edition of this well-known textbook demonstrates their value, scope and use in the synthesis of complex molecules. All the text from the third edition has been completely re-written, making this an up-to-date account of current methods. A valuable textbook for students of and biochemistry at the graduate and senior undergraduate levels, the volume will also interest practicing scientists in industry and establishments who wish to familiarize themselves with modern synthetic methods. Previous Edition Hb (1987): 0-521-32234-0 Previous Edition Pb (1987): 0-521-31117-9.

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Practical HPLC Method Development, 2nd Edition, 1997-03

Practical HPLC Method Development, 2nd Edition, 1997-03
By: Lloyd R. Snyder, Joseph J. Kirkland, Joseph L. Glajch
ISBN: 047100703X
Publisher: Wiley-Interscience - 1997-03-03
Hardcover | 2nd Edition | 765 Pages | List Price: $128.00 (USD) | Sales Rank: 139105.

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The Future of U.S. Chemistry Research: Benchmarks and Challenges

Publisher: National Academies Press
  • Number Of Pages: 160
  • Publication Date: 2007-06-08
  • ISBN-10 / ASIN: 0309105331
  • ISBN-13 / EAN: 9780309105330
  • Binding: Paperback.
DOWNLOAD LINK:

ifile.it

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Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation

Publisher: Wiley
  • Number Of Pages: 862
  • Publication 2007-12-04
  • ISBN-10 / ASIN: 0470516348
  • ISBN-13 / EAN: 9780470516348
  • BProduct Description:

    Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and , the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references.

    This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry.

    http://rapidshare.com/files/145248100/introduction_mass_spectrometry_instrumenattion_4th.rar

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Data Analysis for Chemists

  • Publisher:
  • Number Of Pages:
  • Publication Date:
  • ISBN-10 / ASIN: 0198557272
  • ISBN-13 / EAN: 9780198557272
  • Binding: Hardcove

http://rapidshare.com/files/144975835/0198557272.rar

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Crystallization Process Systems

  • Butterworth-Heinemann
  • Number Of Pages: 352
  • Publication 2002-06-15
  • ISBN-10 / ASIN: 0750655208
  • ISBN-13 / EAN: 9780750655200
  • Binding: Hardcover
Product Description:

Crystallization Process Systems gives a clear, concise, balanced and up to date of crystallization and solid-liquid separation of the crystalline product. The information is presented in a coherent, concise and logical sequence based on the fundamentals of particulate crystallization processes as systems.



By emphasising the analysis, design and operation of particulate crystallization processes as systems, the reader will be able to make a better judgement about the best, cheapest and most effective production method to use.

Crystallization Process Systems gives a wider view and an overview of the subject of crystallization as a whole. It provides an ideal lead-in to more specialized works such as Crystallization and Solid-Liquid Separation - also published by BH.

Presents a coherent, concise and logical sequence based on the fundamentals of particulate crystallization processes as systemsEmphasis on the design and optimization of the crystallization processing system.

http://rapidshare.com/files/112872328/crypro.rar



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Introduction to Modern Liquid Chromatography

Introduction to Modern Liquid Chromatography
By Lloyd R. Snyder, Joseph J. Kirkland
  • Wiley-Interscience
  • Number Of Pages: 896
  • Publication Date: 1979-10
  • ISBN-10 / ASIN: 0471038229
  • ISBN-13 / EAN: 9780471038221
  • Binding: Hardcover
Product Description:

This Second Edition incorporates the latest developments in the practical of LC. Covers the basic of LC, the six LC methods and their and various specialized areas. Provides material for in-depth comprehension of how HPLC is performed, what the necessary materials are, and possible applications. Offers thorough treatment of such areas as quantitative and qualitative analysis by HPLC, preparative scale separations, gradient elution and column-switching, sample pretreatment and reaction detectors, automated systems for high-volume testing and/or samples requiring pretreatment, troubleshooting and sample artifacts, and selection and development of LC method for a particular applications.

http://rapidshare.com/files/2959264/Introduction_to_Modern_Liquid_Chromatography__0471038229_.rar

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Strategies and Tactics in Organic Synthesis, Volume 5 (Strategies and Tactics in Organic Synthesis)

Academic Press
  • Number Of Pages: 512
  • Publication
  • 2004-11-03
  • ISBN-10 / ASIN: 0124502865
  • ISBN-13 / EAN: 9780124502864
  • Binding: Paperback
Product Description:
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for to discuss their approach to the science and art of organic synthesis. Rather than a simple data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project.
In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

- Personal accounts of research in organic chemistry.
- Written by internationally renowned scientists.
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Principles of Fermentation Technology


Principles of Fermentation Technology
By P. F. Stanbury, A. Whitaker, and S. J. Hall
Publisher: Butterworth-Heinemann
  • Number Of Pages: 376
  • Publication Date: 1999-05-03
  • ISBN-10 / ASIN: 0750645016
  • ISBN-13 / EAN: 9780750645010
  • Binding: Paperback

http://rapidshare.com/files/91213140/Principles_of_Fermentation_Technology.pdf

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Handbook on the Toxicology of Metals, Third Edition

Publisher: Academic Press
Number Of Pages: 992
Publication Date: 2007-05-25
Description:
Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds.
Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter
New chapters on general chemistry , biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more

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http://mihd.net/jn86vq/__ac28b02__.html
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Metal Oxide Chemistry and Synthesis: From Solution to Solid State

Description:
The precipitation of metal oxides from aqueous solutions creates nanoparticles with interesting solid state properties, thus building a bridge between solution chemistry and solid state chemistry. This book is the first monograph to deal with the formation of metal oxides from aqueous solutions with emphasis on the formation and physical chemistry of nanoparticles.

Metal Oxide Chemistry and Synthesis: From Solution to Solid State
Provides a comprehensive introduction to the synthesis of finely divided materials
Presents the chemistry, physics and applications of these materials
Builds a bridge between classical solution chemistry and new developments in solid state chemistry
Introduces an important new area in inorganic chemistry
Part I examines the mechanism of condensation of aqueous cations leading to polynuclear species or lattices, and rationalizes the behaviour of cations in precipitation phenomena by identifying pathways from soluble species to solids. The cation complex is also analysed in relation to the synthesis of some technologically interesting polymetallic oxides, e.g. ferroelectric, ferrimagnetic and supraconductor materials.

Part II is devoted to the surface chemistry of oxide particles. The basic concepts relating to the reactivity of the oxide-solution interface are introduced and applied to various adsorption phenomena, such as aggregation, stability of particle size against ripening, etc. These properties are exploited for the synthesis of nanomaterials for a broad range of applictions such as ceramic powders, catalysts and nanocomposites. This will also be of interest to those wishing to understand geochemical and some biological processes.

As well as being invaluable to researchers and postgraduate students of inorganic chemistry , this book will also be appreciated by solid-state chemists, materials scientists and colloid chemists with an interest in metal oxides.

http://rapidshare.com/files/28155183..._Synthesis.rar
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Carbonated Soft : Formulation and Manufacture

Publisher: Wiley-Blackwell
Number Of Pages: 368
Publication Date: 2006-09-11
Description:
The market for carbonated beverages has grown dramatically over recent years in most countries, and this growth has required changes in the way factories are run. Like other food products], soft drinks are required to be produced under stringent hygiene conditions. Filling technology has progressed rapidly to meet the needs of manufacturers and consumers alike. Packaging choices have changed and there have been improvements in closure design.
This book provides an overview of carbonated soft drinks production in the early part of the twenty first century, presenting the latest information on carbonation and filling methods. There are also chapters on bottle design , can making, general packaging considerations, production and distribution. A final chapter deals with quality assurance, and environmental and legislative issues. Detailed references provide opportunity for further reading in more specialised areas. The book is aimed at graduates in food science, chemistry, microbiology and engineering who are considering a career in the soft drinks industry, as well as technical staff already employed within the industry and associated suppliers.
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