Profiles of Drug Substances, Excipients and Related Methodology

Book Description:

Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic.

The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

* Presents comprehensive reviews covering all aspects of drug development and formulation of drugs
* Now encompassing critical review chapters
* Meets the information needs of the drug development community.

DOWNLOAD LINK:

Volume:33

http://rapidshare.com/files/87190761/Pro_Drug_Sub_E_Vol33.zip

Volume:31

http://rapidshare.com/files/101822099/Profiles_of_Drug_Substances__Excipients_and_Related_Methodology__Volume_31__Profiles_of_D.rar

Volume:30

http://rapidshare.com/files/77514691/Profiles_of_Drug_Substances_Excipients_and_Related_Methodology_.rar

Volume:27

http://rapidshare.com/files/136435803/tanaprodrug_Subs_exp_vol27.zip

Volume:28

http://rapidshare.com/files/101812843/Analytical_Profiles_of_Drug_Substances_and_Excipients__Volume_28__Profiles_of_Drug_Substances__Excip

Volume:29

http://rapidshare.com/files/81555455/Analytical_Profiles_of_Drug_Substances_and_Excipients__Volume_29.rar

Toxicology of Solvents.

Toxicology of Solvents.
By M. McParland, N. Bates

---

• Publisher: Rapra Technology Ltd
• Number Of Pages: 400
• Publication Date: 2001-12
• ISBN-10 / ASIN: 1859572960
• ISBN-13 / EAN: 9781859572962
• Binding: Hardcover

---

About the Author:

The Medical Toxicology Unit at Guy’s and St Thomas’ Hospital in London is one of the largest specialist toxicology units in the world, providing information about poisoning to health professionals via a 24 hour telephone service. The National Poisons Information Service (London) has been operating for over 30 years and is one of the busiest in the world, handling the majority of the 200,000 calls made each year in the UK.

All contributors are Poisons Information Specialists at the Medical Toxicology Unit, with extensive experience in advising the UK National Health Service on the consequences of chemical accidents and chemical exposures.

DOWNLOAD LINK:

http://rapidshare.com/files/148651759/1859572960.rar

Analysis of Plastics

Analysis of Plastics (Rapra Review Reports)
By M, J Forrest

---

• Publisher: Smithers Rapra Technology
• Number Of Pages: 160
• Publication Date: 2002-05-01
• ISBN-10 / ASIN: 1859573339
• ISBN-13 / EAN: 9781859573334
• Binding: Paperback.

DOWNLOAD LINK:
http://rapidshare.com/files/148649122/1859573339.rar

Pharmaceutical Process Engineering

Pharmaceutical Process Engineering (Drugs and the Pharmaceutical Sciences)
By Anthony J. Hickey

---

• Publisher: Informa HealthCare
• Number Of Pages: 286
• Publication Date: 2001-03-15
• ISBN-10 / ASIN: 0824702980
• ISBN-13 / EAN: 9780824702984
• Binding: Hardcover

---

Product Description:

Summarizing fundamental engineering principles and operations critical to converting bulk pharmaceutical products into patient-ready and appropriate drug delivery dosage forms, Pharmaceutical Process Engineering facilitates comprehensive understanding of the practical aspects of drug production in an accessible, step-by-step format. It provides a pharmaceutical perspective on unit operations that improves communication among diverse professionals in the field-from pharmaceutical researchers to chemical and industrial engineers-and fully covers the relationship of pharmaceutical development to the application of key concepts and major unit operations in pharmaceutical engineering.

DOWNLOAD LINK:

http://rapidshare.com/files/18809247/PPE.rar.html

Advances in Crystal Growth Inhibition Technologies

Advances in Crystal Growth Inhibition Technologies
By Zahid Amjad

---

• Publisher: Springer
• Number Of Pages: 278
• Publication Date: 2000-12
• ISBN-10 / ASIN: 0306464993
• ISBN-13 / EAN: 9780306464997
• Binding: Hardcover

---

Product Description:

In this book, academic researchers and technologists will find important information on the interaction of polymeric and non-polymeric inhibitors with a variety of scale forming crystals such as calcium phosphates, calcium carbonate, calcium oxalates, barium sulfate, calcium pyrophosphates, and calcium phosphonates. Moreover, the book delivers information to plant managers and formulators who would like to broaden and deepen their knowledge about processes involved in precipitation of sparingly soluble salts and learn more about the inhibitory aspects of various commercially available materials. Furthermore, experienced researchers will obtain fruitful and inspiring ideas from the easily accessible information about overlapping research areas, which will promote discoveries of new inhibitors (synthetic and/or natural) for the currently unmet challenges.

DOWNLOAD LINK:

http://rapidshare.com/files/7749348/AdvancesInCrystalGrowthInhibitionTechnologies.rar

Hansen Solubility Parameters: A User's Handbook, Second Edition

Hansen Solubility Parameters: A User's Handbook, Second Edition
By Charles M. Hansen

---

• Publisher: CRC
• Number Of Pages: 544
• Publication Date: 2007-06-15
• ISBN-10 / ASIN: 0849372488
• ISBN-13 / EAN: 9780849372483
• Binding: Hardcover

---

Product Description:

Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including polymers, inorganic salts, and biological materials.

To update his groundbreaking handbook with the latest advances and perspectives, Charles M. Hansen has invited five renowned experts to share their work, theories, and practical applications involving HSPs. New discussions include a new statistical thermodynamics approach for confirming existing HSPs and how they fit into other thermodynamic theories for polymer solutions. Entirely new chapters examine the prediction of environmental stress cracking as well as absorption and diffusion in polymers. Highlighting recent findings on interactions with DNA, the treatment of biological materials also includesskin tissue, proteins, natural fibers, and cholesterol. The book also covers the latest applications of HSPs, such as ozone-safe “designer” solvents, protective clothing, drug delivery systems, and petroleum applications.

Presenting a comprehensive survey of the theoretical and practical aspects of HSPs, Hansen Solubility Parameters, Second Edition concludes with a detailed discussion on the necessary research, future directions, and potential applications for which HSPs can provide a useful means of prediction in areas such as biological materials, controlled release applications, nanotechnology, and self-assembly.

DOWNLOAD LINK:

http://rapidshare.com/files/86165210/HSPAUH2ndEdCrc.rar

Practical Process Research & Development

Practical Process Research & Development
By Neal G. Anderson

• Publisher: Academic Press
• Number Of Pages: 354
• Publication Date: 2000-04-15
• ISBN-10 / ASIN: 0120594757
• ISBN-13 / EAN: 9780120594757
• Binding: Hardcover

---

Product Description:

This book will provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine
chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key
compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are
identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and
academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent,
and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students.

* Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules"
* Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more
* Includes over 100 tips for rapid process development
* Presents guidelines for implementing and troubleshooting processes.

DOWNLOAD LINK:

http://rapidshare.com/files/59056383/Practical-Process-Research_Development.rar

Chiral Separation Techniques (Third Edition)

• Publisher: 2007 Wiley-VCH Verlag GmbH & Co. KGaA

• Number Of Pages: 619
• Publication Date: 20 Sep 2007
• Sales Rank:
• ISBN / ASIN: Print ISBN: 9783527315093 Online ISBN: 9783527611737
• EAN:
• Binding:
• Manufacturer:
• Studio:
• Average Rating:
• Total Reviews:

---

Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.

DOWNLOAD LINK:

http://rapidshare.com/files/64288637/CST3.rar

Pharmaceutical Production Facilities: Design and Applications

Pharmaceutical Production Facilities: Design and Applications (Taylor & Francis Series in Pharmaceutical Sciences)
By Graham Cole

---

• Publisher: Informa HealthCare
• Number Of Pages: 342
• Publication Date: 1998-02-11
• ISBN-10 / ASIN: 0748404384
• ISBN-13 / EAN: 9780748404384
• Binding: Hardcover

---

Product Description:

Pharmaceutical Production Facilities: Design and Applications considers the concepts and constraints that have to be considered in the design of small, medium and large scale production plants. The layout, along with the flow of materials and personnel through facilities are considered with reference to ensuring compliance with current good manufacturing practice. The book explains how clean rooms have developed, and how recent regulations affect their design. The latest concepts for reducing contamination levels from the operator and the product are discussed. It assess current changes in standards and quality control and makes suggestions for the "ideal production environment" to enable standards to be validated to current standards.

DOWNLOAD LINK:

http://rapidshare.com/files/147707299/0748404384.zip

Bioassay Techniques for Drug Development

Bioassay Techniques for Drug Development
By Atta-ur Rahman, MI Choudhary, W Thompson

---

• Publisher: Informa HealthCare
• Number Of Pages: 232
• Publication Date: 2001-09-14
• ISBN-10 / ASIN: 9058230511
• ISBN-13 / EAN: 9789058230515
• Binding: Hardcover

---

Product Description:

The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The contents detail a number of enzyme-based assays, cell-based functional bioassays and receptor radioligand binding assays along with detailed descriptions of each type. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry or pharmacology.

DOWNLOAD LINK:

http://rapidshare.com/files/148356796/9058230511.zip

Pharmaceutical Product Strategy: Using Dynamic Modeling for Effective Brand Planning

• Publisher: Informa HealthCare
• Number Of Pages: 328
• Publication Date: 2004-12-28
• ISBN-10 / ASIN: 0849327296
• ISBN-13 / EAN: 9780849327292
• Binding: Hardcover

---

Product Description:

Borrowing time-tested Dynamic Modeling (DM) techniques from engineering, the authors illustrate the concept and resulting power of the DM methodology in pharmaceutical product development and brand management. The book examines issues surrounding utilization of information, consistency of assumptions, and the need for approaches that integrate the institutional knowledge of various functional areas as well as leverage the vast amount of secondary data available in the pharmaceutical industry. The authors detail how the DM approach facilitates the brand planning process in a systematic and accessible way. Issues of patient flow dynamics, physician adoption and prescribing patterns, as well as evaluation frameworks for specific treatment regimens are thoroughly examined. A later chapter details the extension of the DM framework to issues of pipeline portfolio management using agent-based modeling techniques and uncertainty formulations.

DOWNLOAD LINK:

http://rapidshare.com/files/149010719/0849327296.rar

---

Immunoassay: A Practical Guide

Immunoassay: A Practical Guide
(Ellis Horwood Series in Pharmaceutical Technology)
By Brian Law

---

• Publisher: CRC
• Number Of Pages: 222
• Publication Date: 1996-10-04
• ISBN-10 / ASIN: 0748405607
• ISBN-13 / EAN: 9780748405602
• Binding: Library Binding

---

Product Description:

Immunoassay development is a multidisciplinary activity involving a wide range of skills possessed by few laboratories. This presentation of tried and tested methods should enable scientists and researchers in the pharmaceutical and related industries to more rapidly and effectively develop immunoassays upon which their work is becoming heavily dependent.; Important methods are included for preparing Lapten-protein conjugates and raising the necessary antibodies, concentrating on polyclonal sera, as well as methods for the synthesis of radio and enzyme labelled tracers. Particular attention is paid to the requirements of the regulatory authorities such as the FDA (Food and Drug Administration) with respect to assay validation. Further chapters deal with assay development and optimization, curve fitting and quality control procedures.

DOWNLOAD

http://rapidshare.com/files/148865515/0748405607.rar

LINK:

Toxicology of industrial compounds

Toxicology of industrial compounds
By H. Thomas

---

• Publisher: CRC
• Number Of Pages: 448
• Publication Date: 1995-12-01
• ISBN-10 / ASIN: 074840239X
• ISBN-13 / EAN: 9780748402397
• Binding: Library Binding

---

Product Description:

A large number of chemical compunds are constantly being introduced and produced, both to assist and ease modern human life. Among these chemicals, industrial compounds represent a particular fraction of chemicals which are not intended for use in biological systems, but to which humans may be accidently exposed, whether in the workplace, by product application, or via the environment. Industrial chemicals, as opposed to pharmaceuticals and agrochemicals, are in many cases subjected only to a very basic examination of handling safety, and may lack further toxicity testing. This implies that essentially nothing is known about their bioavailability, metabolism, excretion and toxicological properties, unless problems arise.; Covering the investigation of industrial chemicals, this book focuses on their individual structure, biological fate, potential toxicity to mammals and the molecular mechanisms possibly underlying their adverse effects by highlighting the use and significance of experimental toxicology. Special emphasis is placed on mechanistic aspects in the safety assessment of industrial compounds, in addition to current regulatory and legal considerations.

DOWNLOAD LINK:

http://rapidshare.com/files/148896263/074840239X.zip

Handbook of Aqueous Solubility Data

Handbook of Aqueous Solubility Data
By Samuel H. Yalkowsky, Yan He

---

• Publisher: CRC
• Number Of Pages: 1512
• Publication Date: 2003-03-26
• ISBN-10 / ASIN: 0849315328
• ISBN-13 / EAN: 9780849315329
• Binding: Hardcover

---

Product Description:

Over the years researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until now, this information has been scattered throughout the literature. Containing over 16,000 solubility data points for more than 4,000 organic compounds, Handbook of Aqueous Solubility Data provides an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, agricultural, industrial, and energy related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CAS Registry Number, melting point, and boiling point if available. Each entry has a five-point evaluation score for the quality of the reporting of the data, along with the full citation, and comments from the authors when necessary. The user-friendly format gives a clear depiction of each piece of solubility data with enough information to estimate its validity. Handbook of Aqueous Solubility Data gives you a portable, accessible resource for solubility data of numerous compounds and a single system for the evaluation of the data supplied.

DOWNLOAD LINK:

http://rapidshare.com/files/149093245/0849315328.zip

Chemical Properties Handbook: Physical, Thermodynamics, Engironmental Transport, Safety & Health Related Properties for Organic & Inorganic Chemical

Chemical Properties Handbook: Physical, Thermodynamics, Engironmental Transport, Safety & Health Related Properties for Organic & Inorganic Chemical
By Carl Yaws

---

• Publisher: McGraw-Hill Professional
• Number Of Pages: 784
• Publication Date: 1998-10-01
• ISBN-10 / ASIN: 0070734011
• ISBN-13 / EAN: 9780070734012
• Binding: Hardcover

---

Product Description:

Necessary data that's often hard to find or difficult to calculate, all in one place, in easy-access format. That's what this Handbook provides to scientific, engineering, and environmental professionals, and students, who seek information on how chemicals will behave at different temperatures and under different conditions. Covering both organic and inorganic substances, and providing both experimental values and estimated values based on methods developed by the author and other noted experts, this book can save countless hours of searching for the right source or performing complicated calculations. Useful for hundreds of on-the-job information requirements, this much-needed Handbook makes it easy to obtain critical values for temperature and pressure for design or operation of compressors and turbines; find heat capacity data for heat exchangers; accurately design and safely operate vaporizers and condensers with precise information on enthalpy of vaporization; size vaporizer/condenser storage vessels with density data; determine the heating and cooling requirements of reactors with values for the enthalpy of formation; determine chemical equilibria for reactions using Gibbs’ energy of formation; design and operate effective stripping operations for water pollutant removal using water solubility data and Henry’s Law Constant; find needed adsorption capacities of activated carbon for cleaning air of various pollutants; use soil sorption coefficient for agricultural applications; solve problems for fluid flow of gases and liquids using viscosity data; use thermal conductivity data for heat transfer applications; use lower and upper explosion limits in air, flock point and autoignition temperature for safety in designs and operations; use threshold limit value (ACGIH), permissible exposure limit (OSHA) and recommended exposure limit (NIOSH) to design facilities while safeguarding health; use thermal expansion coefficient data to design relief systems; and find thousands of other time-saving uses.

DOWNLOAD LINK:

http://rapidshare.com/files/8045931/Chemical.Properties.Handbook-0070734011.rar

The Art of Problem Solving in Organic Chemistry

The Art of Problem Solving in Organic Chemistry
By Miguel E. Alonso

---

• Publisher: Wiley-Interscience
• Number Of Pages: 336
• Publication Date: 1987-01
• ISBN-10 / ASIN: 0471847844
• ISBN-13 / EAN: 9780471847847
• Binding: Hardcover

---

Product Description:

For students of advanced organic chemistry, this text develops problem-solving skills using fifty-six challenging, organic chemistry problems covering a wide variety of chemical systems. Concentrates on necessary and fundamental concepts in the introductory chapters. Valuable not only as a study guide and source of interesting problems, but also as an illustration of reactions and phenomena of general interest.

DOWNLOAD LINK:

http://rapidshare.com/files/105815752/the_art_of_problem_solving_in_organic_chemistry_-_m._alonso__1987__ww.pdf

Design of Experiments in Chemical Engineering: A Practical Guide

Design of Experiments in Chemical Engineering: A Practical Guide
By Zivorad R. Lazic

---

• Publisher: Wiley-VCH
• Number Of Pages: 620
• Publication Date: 2005-01-04
• ISBN-10 / ASIN: 3527311424
• ISBN-13 / EAN: 9783527311422
• Binding: Hardcover

---

Product Description:

While existing books related to DOE are focused either on process or mixture factors or analyze specific tools from DOE science, this text is structured both horizontally and vertically, covering the three most common objectives of any experimental research:

• screening designs
• mathematical modeling, and
• optimization

Written in a simple and lively manner and backed by current chemical product studies from all around the world, the book elucidates basic concepts of statistical methods, experiment design and optimization techniques as applied to chemistry and chemical engineering. Throughout, the focus is on unifying the theory and methodology of optimization with well-known statistical and experimental methods.

The author draws on his own experience in research and development, resulting in a work that will assist students, scientists and engineers in using the concepts covered here in seeking optimum conditions for a chemical system or process.
With 441 tables, 250 diagrams, as well as 200 examples drawn from current chemical product studies, this is an invaluable and convenient source of information for all those involved in process optimization.

DOWNLOAD LINK:

http://rapidshare.com/files/115693900/_2__DESIGN_OF_EXPERIMENTS_IN_CHEMICAL_ENGINEERING.pdf

Handbook of Chemical Reactor Design, Optimization, and Scaleup

Handbook of Chemical Reactor Design, Optimization, and Scaleup

By Bruce Nauman

---

• Publisher: McGraw-Hill Professional
• Number Of Pages: 600
• Publication Date: 2001-09-26
• ISBN-10 / ASIN: 0071377530
• ISBN-13 / EAN: 9780071377539
• Binding: Hardcover

---

Product Description:

Black, gold foil-enhanced frame holds an 8 1/2 x 11 certificate. Built-in hook and easel allows wall or desktop display. Features black book bound edges and a clear acetate window to protect the award. Includes one sheet of 24 lb. ivory parchment paper.

DOWNLOAD LINK:

http://rapidshare.com/files/92260542/chredeopsc.rar

Modern Spectroscopy

Modern Spectroscopy
By J. Michael Hollas

---

• Publisher: Wiley
• Number Of Pages: 480
• Publication Date: 2004-01-16
• ISBN-10 / ASIN: 0470844167
• ISBN-13 / EAN: 9780470844168
• Binding: Paperback

---

Product Description:

The latest edition of this highly acclaimed title introduces the reader to a wide range of spectroscopies, and includes both the background theory and applications to structure determination and chemical analysis. It covers rotational, vibrational, electronic, photoelectron and Auger spectroscopy, as well as EXAFs and the theory of lasers and laser spectroscopy.

• A revised and updated edition of a successful, clearly written book
• Includes the latest developments in modern laser techniques, such as cavity ring-down spectroscopy and femtosecond lasers
• Provides numerous worked examples, calculations and questions at the end of chapters.

DOWNLOAD LINK:

http://rapidshare.com/files/12519645/Modern_Spectroscopy_0470844167.rar

Vogel's Textbook of Practical Organic Chemistry (5th Edition)

Vogel's Textbook of Practical Organic Chemistry (5th Edition)
By A.I. Vogel, A.R. Tatchell, B.S. Furnis, A.J. Hannaford, P.W.G. Smith

---

• Publisher: Prentice Hall
• Number Of Pages: 1552
• Publication Date: 1996-02-19
• ISBN-10 / ASIN: 0582462363
• ISBN-13 / EAN: 9780582462366
• Binding: Hardcover

---

Product Description:

Most widely used, established and respected reference manual for the organic chemistry laboratory. Incorporates new reactions and techniques now available to the organic chemist.

DOWNLOAD LINK:

Mirror
type: RAR
size: 12.9 MB
VogelOrgChem.rar
RAR archive password: "gigapedia.org"
original filename: Vogel's Textbook of Practical Organic Chemistry 5th Ed. (Furnis B.S. et all, Longman 1989)
PDF version
size: 14.7 MB

---

#1	rapidshare.com

Lange's Handbook of Chemistry

Lange's Handbook of Chemistry

By John A. Dean

• Publisher: McGraw-Hill Professional
• Number Of Pages: 1424
• Publication Date: 1998-10-30
• ISBN-10 / ASIN: 0070163847
• ISBN-13 / EAN: 9780070163843
• Binding: Hardcover

---

Product Description:

Revered as the standard reference for chemists for more than 60 years, this new edition of Lange's brings chemistry professionals, students, and anyone interested in science an enormous compilation of facts, data, tabular material, and experimental findings in every area of chemistry. Included in this massive compendium are listings of the properties of approximately 4,000 organic and 1,400 inorganic compounds. The 15th Edition includes new material on separation methods and analytical chemistry; statistical methods; polymers; rubbers, fats, oils, and waxes; new inorganic compounds; IUPAC nomenclature of organic compounds; updated lists of physical and chemical symbols; definitions and abbreviations; new tables, charts, and illustrations; with SI units used throughout (conversion tables supplied). The American Technical Technologists' Events magaine said of the last edition of this book, "Bargains are rare in the publication arena but this book represents one ... it is just overflowing with useful information that is available at your beck and call."

DOWNLOAD LINK:

http://rapidshare.com/files/99907217/lange_s.handbook.of.chemistry.rar

Synthetic Nitrogen Products: A Practical Guide to the Products and Processes

Synthetic Nitrogen Products: A Practical Guide to the Products and Processes
By Gary Maxwell

---

• Publisher: Springer
• Number Of Pages: 388
• Publication Date: 2004-05-19
• ISBN-10 / ASIN: 0306482258
• ISBN-13 / EAN: 9780306482250
• Binding: Hardcover

---

Book Description:

This book provides a comprehensive description of 1) products that are made from or that contain nitrogen, 2) the processes that produce these products and 3) the markets that consume these products. The goal has been to present an abundance of information in one book so that the reader will find the maximum amount of useful information in one place.
The first four chapters provide basic information about nitrogen and nitrogen products and processes. Chapters 5 through 20 provide detailed descriptions of various nitrogen or nitrogen-containing products. The material is presented in a standardized format that should make this book easy to use and helpful to all readers. A wide variety of readers in countries around the world should find the book useful - from students to professors, to technical professionals to business marketing personnel.

DOWNLOAD LINK:

http://rapidshare.com/files/103379019/synnitpro.rar

Thermal Analysis of Pharmaceuticals

Thermal Analysis of Pharmaceuticals
By Duncan Q.M. Craig, Mike Reading

---

• Publisher: CRC
• Number Of Pages: 416
• Publication Date: 2006-12-21
• ISBN-10 / ASIN: 0824758145
• ISBN-13 / EAN: 9780824758141
• Binding: Hardcover

---

Product Description:

As a result of the Process Analytical Technologies (PAT) initiative launched by the U.S. Food and Drug Administration (FDA), analytical development is receiving more attention within the pharmaceutical industry. Illustrating the importance of analytical methodologies, Thermal Analysis of Pharmaceuticals presents reliable and versatile characterization tools for the successful development of pharmaceutical products. It draws attention to the most widely applicable methods and demonstrates how to interpret the associated data.

The book opens with the first three chapters devoted to differential scanning calorimetry (DSC), the most commonly used thermal method. These chapters cover the principles, optimal use, and pharmaceutical applications of the method. Subsequent chapters explore modulated temperature DSC, thermogravimetric analysis, thermal microscopy, microcalorimetry, high sensitivity DSC, dynamic mechanical analysis, and thermally stimulated current, all of which have attracted great interest within the pharmaceutical field. The chapters include theoretical background, measurement optimization, and pharmaceutical applications of each technique.

Exploring important techniques for characterizing the physical structure and properties of pharmaceutical materials, Thermal Analysis of Pharmaceuticals achieves an ideal balance in the depth, relevance, and accessibility of topics presented. The book provides an excellent overview of this key area in pharmaceutical development.

DOWNLOAD LINK:

http://rapidshare.com/files/139900103/Thermana_pharma.zip

Asymmetric Phase Transfer Catalysis

Asymmetric Phase Transfer Catalysis
By Keiji Maruoka

---

• Publisher: Wiley-VCH
• Number Of Pages: 228
• Publication Date: 2008-04-18
• ISBN-10 / ASIN: 3527318429
• ISBN-13 / EAN: 9783527318421
• Binding: Hardcover

Product Description:

Edited by the leading expert on the topic, this is the first book to present the latest developments in this exciting field. Alongside the theoretical aspects, the top contributors provide practical protocols to give readers additional important information otherwise unavailable.
A must for every synthetic chemist in academia and industry.

DOWNLOAD LINK:

http://rapidshare.com/files/140421356/apasdlfadwd3527318429.rar

Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes

• Publisher: Elsevier Science
• Number Of Pages: 532
• Publication Date: 2007-05-07
• ISBN-10 / ASIN: 0444527109
• ISBN-13 / EAN: 9780444527103
• Binding: Hardcover

Product Description:

Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes stems from the experience of the EC funded project DEMETRA. This project combined institutes involved in the regulatory process of pesticides, industries of the sector and scientists to develop and offer original software for the prediction of ecotoxicity of pesticides. Then to be used within the dossier preparation for pesticide registration. The basis of this book is more than three-years of research activities, discussions, studies and successful models. This experience represents a useful example not only for the case of pesticides, but also for the prediction of ecotoxicity and toxicity in general.

QSAR is used to link a given property of a chemical compound with some features related to its structure. The theoretical toxicological, chemical and information technology aspects will be treated considering the regulatory issues. Innovative hybrid systems will be described, for the toxicity prediction of pesticides and related compounds, directly useful for pesticide evaluation within the Dossier preparation for pesticide registration. Five endpoints will also be discussed, addressing issues as standardisation, verification, validation, accessibility, reproducibility.

The driving force for Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes is that all the issues of concern for end-users are analysed, discussed and solutions proposed further. An innovative feature is that, in order to offer powerful QSAR models, the book discusses and reports on integrated QSAR models, combined into a unique hybrid system.

* Assesses the needs of regulators for pesticide approval and how these needs affect QSAR models
* Combines theoretical discussion with practical examples, including five worked examples of hybrid systems
* Refers to original software available through the internet.

DOWNLOAD LINK:

http://rapidshare.com/files/140662700/Structure-Activity.rar

Re-Evaluation of Some Organic Chemicals: Hydrazine & Hydrogen Peroxide

Re-Evaluation of Some Organic Chemicals: Hydrazine & Hydrogen Peroxide (IARC Monographs on the Evaluation of Carcinogenic Risks to H)
By International Agency for Research on Cancer

---

• Publisher: World Health Organization
• Number Of Pages: 1586
• Publication Date: 1999-12
• ISBN-10 / ASIN: 9283212711
• ISBN-13 / EAN: 9789283212713
• Binding: Paperback

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

Volume 71 (1999)
Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide.

DOWNLOAD LINK:

http://rapidshare.com/files/143747606/mono71.pdf

Ionic Liquids in Synthesis

Ionic Liquids in Synthesis (Green Chemistry (Wiley)(2 vol. set)
By Peter Wasserscheid, Thomas Welton

---

• Publisher: Wiley-VCH
• Number Of Pages: 776
• Publication Date: 2007-12-21
• ISBN-10 / ASIN: 3527312390
• ISBN-13 / EAN: 9783527312399
• Binding: Hardcover

---

Product Description:

The second, completely revised and enlarged edition of what has become the standard reference work in this fascinating field brings together the latest developments, supplemented by numerous practical tips, providing those working in both research and industry with an indispensable source of information. New contributions have been added, to reflect the fact that industrial processes are already established, and ionic liquids are now commercially available.
A must for everyone working in the field.

DOWNLOAD LINK:

http://rapidshare.com/files/145194333/IonicLiquids_978-3-527-31239-9.zip

Stereoselective Synthesis: Workbench Edition - Houben-weyl, Methods of Organic Chemistry

Stereoselective Synthesis: Workbench Edition - Houben-weyl, Methods of Organic Chemistry
By J. Houben, Theodor Weyl

---

• Publisher: Thieme Medical Publishers

• Number Of Pages:
• Publication Date: 1997-01
• ISBN-10 / ASIN: 0865776741
• ISBN-13 / EAN: 9780865776746
• Binding: Hardcover.

All 6 volumes merged in a 7000 pages long pdf file.
A must-have for all synthetic organic-chemists.

#1 rapidshare.com
#2 rapidshare.com
#3 rapidshare.com

SINGLE FILE( Rar-ed single file pdf, no passwd 262 MB):
#1 rapidshare.de

Introduction to Mass Spectrometry

Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation
By J. Throck Watson, O. David Sparkman

Publisher: Wiley
Number Of Pages: 862
Publication Date: 2007-12-04
ISBN-10 / ASIN: 0470516348
ISBN-13 / EAN: 9780470516348
Binding: Hardcover

Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references.

This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry.

DOWNLOAD LINK:

http://rapidshare.com/files/145248100/introduction_mass_spectrometry_instrumenattion_4th.rar

Chromatography of Natural, Treated and Waste Waters

Chromatography of Natural, Treated and Waste Waters
By T R Crompton

Publisher: Taylor & Francis
Number Of Pages: 800
Publication Date: 2003-06-24
ISBN-10 / ASIN: 0415280044
ISBN-13 / EAN: 9780415280044
Binding: Hardcover

Chromatography of Natural, Treated and Waste Waters is the first book to bring together information of a range of chromatographic techniques in all types of water,from precipitation to sewage effluents. Organic and inorganic compounds, cations, anions and elements are all discussed. Particular attention is paid to multi compound analysis of water, and the analysis of minute traces of pollutants. Gas chromatography, high performance liquid chromatography and mass spectrometry are included, and this book is well referenced and easy to use.

DOWNLOAD LINK:

http://rapidshare.com/files/148382271/0415280044.zip

Developing the Leader Within You [Audio book]

Developing the Leader Within You [Audio book] -- John C. Maxwell (Author)
PUB: Thomas Nelson | English | 2004 | ISBN 0785260331 | WMA | 20 MB | 2h 15min
Few of us are natural-born leaders, according to John C. Maxwell, author of Developing the Leader Within You. Fortunately though, "the traits that are the raw material of leadership can be acquired," he promises. "Link them up with desire and nothing can keep you from becoming a leader. This book will supply the leadership principles. You must supply the desire." True to his words, Maxwell offers a detailed and inspiring primer on becoming a leader.

Book Description
After examining the differences between leadership styles, Maxwell outlines principles for inspiring, motivating, and influencing others. These principles can be used in any organization to foster integrity and self-discipline and bring a positive change.

Developing the Leader Within You also allows readers to examine how to be effective in the highest calling of leadership by understanding the five characteristics that set "leader managers" apart from "run-of-the-mill managers."

In this John Maxwell classic, he shows readers how to develop the vision, value, influence, and motivation required of successful leaders.

DOWNLOAD LINK:

Part 1
Part 2
Part 3

Password: www.AvaxHome.ru

ԴID108268 108268

Determination of Organic Compounds in Natural and Treated Waters

Determination of Organic Compounds in Natural and Treated Waters

By T R Crompton

Publisher: Taylor & Francis
Number Of Pages: 928
Publication Date: 1999-11-30
ISBN-10 / ASIN: 0419243607
ISBN-13 / EAN: 9780419243601
Binding: Library Binding

This book draws together and systemizes the vast body of information available on the occurrence and determination of organic substances, providing a comprehensive description of organic compounds in all types of non-saline and saline natural and treated waters. This book is an essential reference for analytical chemists working in industry in the water utilities, those working in government and non-government organizations and regulatory agencies, chemical companies producing aqueous effluents, and for environmental and analytical consultants.

DOWNLOAD LINK:

http://rapidshare.com/files/147682567/0419243607.zip

Instant Notes in Organic Chemistry

Instant Notes in Organic Chemistry (Instant Notes Series)
By Graham Patrick

---

• Publisher: BIOS Scientific Publ

• Number Of Pages: 328
• Publication Date: 2004-03-10
• ISBN-10 / ASIN: 1859962645
• ISBN-13 / EAN: 9781859962640
• Binding: Paperback

---

Product Description:

Instant Notes titles focus on core information and are designed to help undergraduate students come to grips with a subject quickly and easily.

Instant Notes in Organic Chemistry, 2/e concentrates entirely on the basics of the subject without going into exhaustive detail or repetitive examples. This is a student-friendly textbook and will help students understand the subject and encourage easy learning by focusing on the essentials of organic chemistry.

DOWNLOAD LINK:

http://rapidshare.com/files/146203269/1859962645.zip

Stop Faking It! Chemistry Basics

Stop Faking It! Chemistry Basics
By William C. Robertson

Publisher: NSTA Press
Number Of Pages: 112
Publication Date: 2007-01-01
ISBN-10 / ASIN: 0873552393
ISBN-13 / EAN: 9780873552394
Binding: Paperback

Best-selling author Bill Robertson takes a fresh approach to chemistry fundamentals by helping you understand them from the ground up. Instead of hounding you to memorize the characteristics of atoms and the periodic table, Chemistry Basics will help you see those characteristics as a natural consequence of our understanding of

http://rapidshare.com/files/143051341/9780873552394.rar

Instant Notes in Analytical Chemistry (Instant Notes)

Instant Notes in Analytical Chemistry (Instant Notes)

By D. Kealey

Publisher: BIOS Scientific Publ
Number Of Pages: 352
Publication Date: 2002-06-30
ISBN-10 / ASIN: 1859961894
ISBN-13 / EAN: 9781859961896
Binding: Paperback

Instant Notes titles focus on core information and are designed to help undergraduate students come to grips with a subject quickly and easily.

Instant Notes in Analytical Chemistry provides students with a thorough comprehension of analytical chemistry and its applications. This book supports the learning of principles and practice of analytical procedures. It also contains analytical techniques commonly used in laboratories today.

http://rapidshare.com/files/146203179/1859961894.zip

Guidelines for Process Safety Documentation

Guidelines for Process Safety Documentation

By Center for Chemical Process Safety (CCPS)

Publisher: Wiley-AIChE
Number Of Pages: 386
Publication Date: 1995-04-15
ISBN-10 / ASIN: 0816906254
ISBN-13 / EAN: 9780816906253
Binding: Hardcover

The process industry has developed integrated process safety management programs to reduce or eliminate incidents and major consequences, such as injury, loss of life, property damage, environmental harm, and business interruption. Good documentation practices are a crucial part of retaining past knowledge and experience, and avoiding relearning old lessons. Following an introduction, which offers examples of how proper documentation might have prevented major explosions and serious incidents, the 21 sections in this book clearly present aims, goals, and methodology in all areas of documentation. The text contains examples of dozens of needed forms, lists of relevant industry organizations, sources for software, references, OSHA regulations, sample plans, and more.

http://rapidshare.com/files/146088503/Guidelines_Process_Safety_Documentation.rar

Statistical Treatment of Analytical Data

Zeev Alfassi “Statistical Treatment of Analytical Data"
Blackwell | 2004-12-20 | ISBN: 084932436X | 266 pages | PDF | 1,2 MB

Rapidshare Mirror

http://rapidshare.com/files/125804483/StatTreatmAnData.rar

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
By Harmata.

Publisher: Academic Press Number Of Pages: 134 Publication Date: 2005-10-03 ISBN-10 / ASIN: 012450289X ISBN-13 / EAN: 9780124502895 Binding: Paperback

Product Description:

A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

* Presents state-of-the-art developments in organic synthesis
* Provides insight and offers new perspective to problem-solving
* Written by leading experts in the field. http://rapidshare.com/files/140560829/STR.TAC.ORG.SYN.VOL.6.rar

NMR Spectroscopy in Drug Development and Analysis

NMR Spectroscopy in Drug Development and Analysis
By Ulrike Holzgrabe, Iwona Wawer, Bernd Diehl, B Diehl

• Publisher: Wiley-VCH
• Number Of Pages: 299
• Publication Date: 1999-10-15
• ISBN-10 / ASIN: 3527300929
• ISBN-13 / EAN: 9783527300921
• Binding: Hardcover

---

Product Description:

Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis.
This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition of polymer excipients, the characterization of isomeric drug mixtures, the complexity of drugs with small-size components or ions, and the behavior of drugs in acid and basic solution. In addition, NMR spectroscopy and especially the hyphenated technique with HPLC is shown to be a powerful tool to measure a drug and its metabolites in various body fluids. The solid state NMR technique can give information on the structure, especially the conformation of drugs and excipients in drug formulations. Recently, SAR by NMR, introduced by Fesik, impressively demonstrated the potential of NMR spectroscopy in drug development and in the characterization of the interaction between large molecules and ligands. The complexation between proteins, lipids and cyclodextrins with drugs is described. Finally, NMR imaging (MRI and MRS) can be used to characterize the liberation of drugs from a drug formulation. Furthermore, the distribution of substances in plants, in animals, in tissues and in humans can be visualized by imaging.
In short, this book covers all aspects of drug analysis.

http://rapidshare.com/files/114561000/NMR_spectro_dda.zip

Guidelines for Investigating Chemical Process Incidents

Guidelines for Investigating Chemical Process Incidents
By Center for Chemical Process Safety (CCPS)

---

• Publisher: Wiley-AIChE
• Number Of Pages: 452
• Publication Date: 2003-03-15
• ISBN-10 / ASIN: 0816908974
• ISBN-13 / EAN: 9780816908974
• Binding: Hardcover

---

Book Description:

This book provides a valuable reference tool for technical and management personnel who lead or are a part of incident investigation teams. This second edition focuses on investigating process-related incidents with real or potential catastrophic consequences. It presents on-the-job information, techniques, and examples that support successful investigations. The methodologies, tools, and techniques described in this book can also be applied when investigating other types of events such as reliability, quality, occupational health, and safety incidents. The accompanying CD-ROM contains the text of the book for portability as well as additional supporting tools for on-site reference and trouble shooting.

http://rapidshare.com/files/80700905/Investigating_Chemical_Process_Incidents.rar

Plant Guidelines for Technical Management of Chemical Process Safety

by American Institute of Chemical Engineers

---

Plant Guidelines for Technical Management of Chemical Process Safety
By American Institute of Chemical Engineers

---

• Publisher: American Institute of Chemical Engineers
• Number Of Pages: 382
• Publication Date: 1991-06
• ISBN-10 / ASIN: 0816904995
• ISBN-13 / EAN: 9780816904990
• Binding: Hardcover.

http://rapidshare.com/files/78871439/PGTM0816904995.rar

Guidelines for Chemical Reactivity Evaluation and Application to Process Design

Guidelines for Chemical Reactivity Evaluation and Application to Process Design
By Center for Chemical Process Safety (CCPS)

---

• Publisher: Wiley-AIChE
• Number Of Pages: 210
• Publication Date: 1995-04-15
• ISBN-10 / ASIN: 0816904790
• ISBN-13 / EAN: 9780816904792
• Binding: Hardcover

---

Product Description:

Drawn from international sources, this book provides principles and strategies for the evaluation of chemical reactions, and for using this information in process design and management. A useful resource for engineers who design, start-up, operate, and manage chemical and petrochemical plants, the book places special emphasis on the use of state-of-the-art technology in theory, testing methods, and applications in design and operations.

http://rapidshare.com/files/82011213/GCREACRD.rar

Crystallography Made Crystal Clear

Crystallography Made Crystal Clear
By Gale Rhodes

---

Publisher: Academic Press

• Number Of Pages: 269
• Publication Date: 2000-01-15
• ISBN-10 / ASIN: 0125870728
• ISBN-13 / EAN: 9780125870726
• Binding: Paperback

---

Product Description:
Macromolecules are the proteins and nucleic acids upon which life depends. Understanding the action of biological macromolecules (giant molecules) requires detailed knowledge of their structures. Most of the more than ten thousand known structures of protein and nucleic acids were obtained by x-ray crystallography, the standard mechanism for determining protein structure. Essentially, proteins are frozen into rigid crystals, which can be stacked up in a repeating pattern--like supermarket displays. The structure of each individual crystal can be determined by the way x-rays are bent when they pass through the composite crystal. Protein structure is essential when investigating protein interactions and planning drug development.
Crystallography Made Crystal Clear, Second Edition explains how scientists discover the structures of the macromolecules. Scientists do not see these molecules directly. Instead, they build models as a means of interpreting data from x-ray diffraction by crystals, or by irradiation by other forms of energy. Users of these models need to know how they are obtained in order to know what they are seeing when they study a model of a macromolecule. They also need to know how to judge whether conclusions they draw from the molecular models are really supported by the models. This book uses visual and geometric models to help readers understand the mathematics that forms the basis of x-ray crystallography.
The field of protein crystallography is growing every day and has been instrumental in discovering the molecular principles of biology and in discovering new drugs, such as the recent protease inhibitors for AIDS. The field includes the largest percentage of Nobel prizes than any other scientific discipline. Every major university and drug company has a protein crystallography laboratory and this book is an invaluable aid to those wishing to practice protein crystallography or just learn more about how it is actually done.

http://rapidshare.com/files/25534814/CMCC-2nd.rar

Compact Regs Part 11: CFR 21 Part 11 Electronic Records; Electronic Signatures

Compact Regs Part 11: CFR 21 Part 11 Electronic Records; Electronic Signatures .

Compact Regs Part 11: CFR 21 Part 11 Electronic Records; Electronic Signatures (10 Pack)
Publisher: Informa HealthCare Number Of Pages: 24 Publication Date: 2003-10-29 ISBN-10 / ASIN: 0849321867 ISBN-13 / EAN: 9780849321863 Binding: Hardcover Product Description:
The Compact Regs series provides full-text, pocket-sized format (3 3/4 inch x 5 1/2 inch) verbatim reproductions of key US FDA regulations. The texts are complete and have not been altered in any manner from the original sources. They are the perfect low-cost tools for: employees as part of documented GMP training programs, for suppliers/vendors so that they may provide components, labels, and parts with an understanding of FDA requirements, and for each clinical investigator, nurse, and technician to help assure compliance to clinical trial protocols. A keyword index can be found at the end of each booklet.

DOWNLOAD LINK:

#1 ifile.it

Quality (Pharmaceutical Engineering Series)

Quality (Pharmaceutical Engineering Series), Volume 2 (Pharmaceutical Engineering)
By Kate McCormick

---

• Publisher: Butterworth-Heinemann
• Number Of Pages: 275
• Publication Date: 2002-09-24
• ISBN-10 / ASIN: 075065113X
• ISBN-13 / EAN: 9780750651134
• Binding: Paperback

Product Description:

The Pharmaceutical Engineering Series is a comprehensive reference for the pharmaceutical professional covering all aspects from quality, documentation and validation through manufacturing processes to facility design and management. In 'Quality', Dr Kate McCormick provides the reader with comprehensive coverage of this vital subject, including the quality life cycle, management and cost of quality, GMP, auditing and inspections. This book with the others in the series will become a unique source of reference and educational material for the readership.

Case studies and examples make the book of direct practical relevance to the professional in the pharmaceutical industry
Find the answers you are looking for quickly and easily with clear indexing and referencing
Reference to international standards and practice mean this book will be useful wherever you are working.

http://rapidshare.com/files/141452692/QPSAFDDA075065113X.zip

http://rapidshare.com/files/141703188/tqualityvol2.zip

Good Manufacturing Practices and Inspection

Good Manufacturing Practices and Inspection (Quality Assurance of Pharmaceuticals) (Quality Assurance of Pharmaceuticals)
By World Health Organization

---

• Publisher: World Health Organization

• Number Of Pages: 413
• Publication Date: 2007-06-06
• ISBN-10 / ASIN: 9241547081
• ISBN-13 / EAN: 9789241547086
• Binding: Paperback

---

Product Description:

Quality assurance of pharmaceutical products is a continuing concern of WHO. Despite efforts made around the world to ensure a supply of quality and effective medicines, substandard, spurious and counterfeit products still compromise health care delivery in many countries. To respond to the global need for adequate quality assurance of pharmaceuticals, WHO's Expert Committee on Specifications for Pharmaceutical Preparations has over the years made numerous recommendations to establish standards and guidelines and to promote the effective functioning of national regulatory and control systems and the implementation of internationally agreed standards by trained personnel. Many of the relevant documents endorsed by the Committee are reproduced in this volume, providing guidance covering all aspects of good manufacturing practices (GMP). Important texts on inspection are also included. Most of the material has been published separately in the Expert Committee's reports. This compendium brings it together to make it more accessible and of greater practical value to those working in faculties of pharmacy, in medicines regulation and control, and in the pharmaceutical industry.

http://rapidshare.com/files/82928562/9789241547086_eng.pdf

http://rapidshare.com/files/83128479/GMP_Inspect_QA_Pharma.zip

Validation Standard Operating Procedures: A Step by Step Guide for Achieving Compliance in the Pharmaceutical, Medical 2001-12

Validation Standard Operating Procedures: A Step by Step Guide for Achieving Compliance in the Pharmaceutical, Medical
By Syed Imtiaz Haider

---

• Publisher: CRC
• Number Of Pages: 496
• Publication Date: 2001-12-27
• ISBN-10 / ASIN: 1574443313
• ISBN-13 / EAN: 9781574443318
• Binding: Hardcover

---

Product Description:

A comprehensive when-and-how-to-do-it guide, this book and CD-ROM combination provides administrative solutions for achieving compliance with key FDA guidelines on good manufacturing practice (GMP), good laboratory practice (GLP), and validation. The text shows readers how to establish test functions and acceptance criteria in compliance with FDA perspectives. The CD-ROM contains 74 template validation standard operating procedures that users can edit and print, customizing the program to their needs. The book and CD work together to minimize the number of forms used and to ensure that the all the correct forms are used, thus avoiding the stress that usually accompanies an FDA audit.

http://rapidshare.com/files/41853767/vsop.zip

GMP/ISO Quality Audit Manual for Healthcare Manufacturers and Their Suppliers, Sixth Edition

GMP/ISO Quality Audit Manual for Healthcare Manufacturers and Their Suppliers, Sixth Edition, (Volume 2 - Regulations By Leonard Steinborn

---

• Publisher: CRC

• Number Of Pages: 452
• Publication Date: 2004-04-15
• ISBN-10 / ASIN: 0849318475
• ISBN-13 / EAN: 9780849318474
• Binding: Paperback

---

Product Description:

Volume 2 of this set contains the full text of the FDA regulations, EC and IPEC guidelines, and ISO/BSI standards referenced in the checklists furnished in Volume I. The book is presented in an convenient, easy-to-read format, organized to provide fast access to the guidelines and regulations of interest.

http://rapidshare.com/files/145229041/GMqweedeee3ddzz0849318475.zip